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PDB: 634 件

5UYL
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70S ribosome bound with cognate ternary complex base-paired to A site codon (Structure II)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A.
登録日2017-02-24
公開日2017-06-14
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Ensemble cryo-EM elucidates the mechanism of translation fidelity.
Nature, 546, 2017
5DOY
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Crystal structure of the Thermus thermophilus 70S ribosome in complex with antibiotic Hygromycin A, mRNA and three tRNAs in the A, P and E sites at 2.6A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Polikanov, Y.S, Starosta, A.L, Juette, M.F, Altman, R.B, Terry, D.S, Lu, W, Burnett, B.J, Dinos, G, Reynolds, K, Blanchard, S.C, Steitz, T.A, Wilson, D.N.
登録日2015-09-11
公開日2015-12-30
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A.
Mol.Cell, 58, 2015
1FE0
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CRYSTAL STRUCTURE OF CADMIUM-HAH1
分子名称: CADMIUM ION, COPPER TRANSPORT PROTEIN ATOX1, SULFATE ION, ...
著者Wernimont, A.K, Huffman, D.L, Lamb, A.L, O'Halloran, T.V, Rosenzweig, A.C.
登録日2000-07-20
公開日2001-01-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for copper transfer by the metallochaperone for the Menkes/Wilson disease proteins.
Nat.Struct.Biol., 7, 2000
1KLK
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CRYSTAL STRUCTURE OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE TERNARY COMPLEX WITH PT653 AND NADPH
分子名称: Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE
著者Cody, V, Galitsky, N, Luft, J.R, Pangborn, W, Rosowsky, A, Queener, S.F.
登録日2001-12-12
公開日2002-12-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-based enzyme inhibitor design: modeling studies and crystal structure analysis of Pneumocystis carinii dihydrofolate reductase ternary complex with PT653 and NADPH.
Acta Crystallogr.,Sect.D, 58, 2002
5UYN
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70S ribosome bound with near-cognate ternary complex not base-paired to A site codon (Structure I-nc)
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A.
登録日2017-02-24
公開日2017-06-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Ensemble cryo-EM elucidates the mechanism of translation fidelity
Nature, 546, 2017
3IWL
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Crystal structure of cisplatin bound to a human copper chaperone (monomer)
分子名称: 3,3',3''-phosphanetriyltripropanoic acid, Copper transport protein ATOX1, PLATINUM (II) ION, ...
著者Boal, A.K, Rosenzweig, A.C.
登録日2009-09-02
公開日2009-09-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structures of cisplatin bound to a human copper chaperone.
J.Am.Chem.Soc., 131, 2009
1FHI
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SUBSTRATE ANALOG (IB2) COMPLEX WITH THE FRAGILE HISTIDINE TRIAD PROTEIN, FHIT
分子名称: FRAGILE HISTIDINE TRIAD PROTEIN, P1-P2-METHYLENE-P3-THIO-DIADENOSINE TRIPHOSPHATE
著者Pace, H.C, Garrison, P.N, Barnes, L.D, Draganescu, A, Rosler, A, Blackburn, G.M, Siprashvili, Z, Croce, C.M, Huebner, K, Brenner, C.
登録日1997-12-11
公開日1998-06-17
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit.
Proc.Natl.Acad.Sci.USA, 95, 1998
1KX2
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Minimized average structure of a mono-heme ferrocytochrome c from Shewanella putrefaciens
分子名称: HEME C, mono-heme c-type cytochrome ScyA
著者Bartalesi, I, Bertini, I, Hajieva, P, Rosato, A, Vasos, P.R.
登録日2002-01-30
公開日2002-02-13
最終更新日2024-10-16
実験手法SOLUTION NMR
主引用文献Solution structure of a monoheme ferrocytochrome c from Shewanella putrefaciens and structural analysis of sequence-similar proteins: functional implications.
Biochemistry, 41, 2002
1FZH
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METHANE MONOOXYGENASE HYDROXYLASE, FORM II PRESSURIZED WITH XENON GAS
分子名称: CALCIUM ION, FE (III) ION, METHANE MONOOXYGENASE COMPONENT A, ...
著者Whittington, D.A, Rosenzweig, A.C, Frederick, C.A, Lippard, S.J.
登録日2000-10-03
公開日2001-04-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Xenon and halogenated alkanes track putative substrate binding cavities in the soluble methane monooxygenase hydroxylase.
Biochemistry, 40, 2001
1LM0
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Solution structure and characterization of the heme chaperone CcmE
分子名称: cytochrome c maturation protein E
著者Arnesano, F, Banci, L, Barker, P.D, Bertini, I, Rosato, A, Su, X.C, Viezzoli, M.S.
登録日2002-04-30
公開日2002-12-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure and characterization of the heme chaperone CcmE
Biochemistry, 41, 2002
3JC1
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Electron cryo-microscopy of the IST1-CHMP1B ESCRT-III copolymer
分子名称: Charged multivesicular body protein 1b, Increased Sodium Tolerance 1 (IST1)
著者McCullough, J, Clippinger, A.K, Talledge, N, Skowyra, M.L, Saunders, M.G, Naismith, T.V, Colf, L.A, Afonine, P, Arthur, C, Sundquist, W.I, Hanson, P.I, Frost, A.
登録日2015-11-09
公開日2015-12-16
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structure and membrane remodeling activity of ESCRT-III helical polymers.
Science, 350, 2015
4H1Q
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Crystal structure of mutant MMP-9 catalytic domain in complex with a twin inhibitor.
分子名称: CALCIUM ION, Matrix metalloproteinase-9, N-(4-{[(3R)-3-[(biphenyl-4-ylsulfonyl)(propan-2-yloxy)amino]-4-(hydroxyamino)-4-oxobutyl]amino}-4-oxobutyl)-N'-(4-{[(3S)-3-[(biphenyl-4-ylsulfonyl)(propan-2-yloxy)amino]-4-(hydroxyamino)-4-oxobutyl]amino}-4-oxobutyl)benzene-1,3-dicarboxamide, ...
著者Stura, E.A, Vera, L, Cassar-Lajeunesse, E, Nuti, E, Catalani, M.P, Dive, V, Rossello, A.
登録日2012-09-11
公開日2013-04-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Crystallization of bi-functional ligand protein complexes.
J.Struct.Biol., 182, 2013
3F91
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Structural Data for Human Active Site Mutant Enzyme Complexes
分子名称: 2,4-DIAMINO-5-[2-METHOXY-5-(4-CARBOXYBUTYLOXY)BENZYL]PYRIMIDINE, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Cody, V, Pace, J, Makin, J, Piraino, J, Queener, S.F, Rosowsky, A.
登録日2008-11-13
公開日2009-08-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Correlations of Inhibitor Kinetics for Pneumocystis jirovecii and Human Dihydrofolate Reductase with Structural Data for Human Active Site Mutant Enzyme Complexes.
Biochemistry, 48, 2009
1YJT
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Solution structure of the Cu(I) form of the sixth soluble domain A69P mutant of Menkes protein
分子名称: COPPER (I) ION, Copper-transporting ATPase 1
著者Banci, L, Bertini, I, Cantini, F, Migliardi, M, Rosato, A, Wang, S.
登録日2005-01-15
公開日2006-01-03
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献An atomic-level investigation of the disease-causing A629P mutant of the Menkes protein, ATP7A
J.Mol.Biol., 352, 2005
1YJV
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Solution structure of the Cu(I) form of the sixth soluble domain of Menkes protein
分子名称: COPPER (I) ION, Copper-transporting ATPase 1
著者Banci, L, Bertini, I, Cantini, F, Migliardi, M, Rosato, A, Wang, S.
登録日2005-01-15
公開日2006-01-03
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献An atomic-level investigation of the disease-causing A629P mutant of the Menkes protein, ATP7A
J.Mol.Biol., 352, 2005
3F8Y
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Correlations of Human Dihydrofolate Reductase with Structural Data for Human Active Site Mutant Enzyme Complexes
分子名称: 2,4-DIAMINO-5-[2-METHOXY-5-(4-CARBOXYBUTYLOXY)BENZYL]PYRIMIDINE, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Cody, V, Pace, J, Makin, J, Piraino, J, Queener, S.F, Rosowsky, A.
登録日2008-11-13
公開日2009-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Correlations of Inhibitor Kinetics for Pneumocystis jirovecii and Human Dihydrofolate Reductase with Structural Data for Human Active Site Mutant Enzyme Complexes.
Biochemistry, 48, 2009
4N59
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The Crystal Structure of Pectocin M2 at 2.3 Angstroms
分子名称: CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, Pectocin M2, ...
著者Zeth, K, Grinter, R, Roszak, A.W, Cogdell, R.J, Walker, D.
登録日2013-10-09
公開日2014-06-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the atypical bacteriocin pectocin M2 implies a novel mechanism of protein uptake.
Mol.Microbiol., 93, 2014
1FZ8
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METHANE MONOOXYGENASE HYDROXYLASE, FORM II COCRYSTALLIZED WITH DIBROMOMETHANE
分子名称: CALCIUM ION, DIBROMOMETHANE, FE (III) ION, ...
著者Whittington, D.A, Rosenzweig, A.C, Frederick, C.A, Lippard, S.J.
登録日2000-10-03
公開日2001-04-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Xenon and halogenated alkanes track putative substrate binding cavities in the soluble methane monooxygenase hydroxylase.
Biochemistry, 40, 2001
1G5B
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BACTERIOPHAGE LAMBDA SER/THR PROTEIN PHOSPHATASE
分子名称: MANGANESE (II) ION, MERCURY (II) ION, SERINE/THREONINE PROTEIN PHOSPHATASE, ...
著者Voegtli, W.C, White, D.J, Reiter, N.J, Rusnak, F, Rosenzweig, A.C.
登録日2000-10-31
公開日2001-03-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structure of the bacteriophage lambda Ser/Thr protein phosphatase with sulfate ion bound in two coordination modes.
Biochemistry, 39, 2000
1JXN
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Crystal Structure of the Lectin I from Ulex europaeus in complex with the methyl glycoside of alpha-L-fucose
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, CALCIUM ION, MANGANESE (II) ION, ...
著者Audette, G.F, Olson, D.J.H, Ross, A.R.S, Quail, J.W, Delbaere, L.T.J.
登録日2001-09-07
公開日2002-12-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Examination of the Structural Basis for O(H) Blood Group Specificity by Ulex europaeus Lectin I
Can.J.Chem., 80, 2002
1JGT
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CRYSTAL STRUCTURE OF BETA-LACTAM SYNTHETASE
分子名称: BETA-LACTAM SYNTHETASE, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, GLYCEROL, ...
著者Miller, M.T, Bachmann, B.O, Townsend, C.A, Rosenzweig, A.C.
登録日2001-06-26
公開日2001-12-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of beta-lactam synthetase reveals how to synthesize antibiotics instead of asparagine.
Nat.Struct.Biol., 8, 2001
4G0F
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Crystal structure of the complex of a human telomeric repeat G-quadruplex and N-methyl mesoporphyrin IX (P6)
分子名称: DNA (5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), N-METHYLMESOPORPHYRIN, POTASSIUM ION
著者Nicoludis, J.M, Miller, S.T, Jeffrey, P, Lawton, T.J, Rosenzweig, A.C, Yatsunyk, L.A.
登録日2012-07-09
公開日2012-12-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Optimized End-Stacking Provides Specificity of N-Methyl Mesoporphyrin IX for Human Telomeric G-Quadruplex DNA.
J.Am.Chem.Soc., 134, 2012
1FZ9
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Methane monooxygenase hydroxylase, form II cocrystallized with iodoethane
分子名称: CALCIUM ION, FE (III) ION, IODOETHANE, ...
著者Whittington, D.A, Rosenzweig, A.C, Frederick, C.A, Lippard, S.J.
登録日2000-10-03
公開日2001-04-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Xenon and halogenated alkanes track putative substrate binding cavities in the soluble methane monooxygenase hydroxylase.
Biochemistry, 40, 2001
1K3K
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Solution Structure of a Bcl-2 Homolog from Kaposi's Sarcoma Virus
分子名称: functional anti-apoptotic factor vBCL-2 homolog
著者Huang, Q, Petros, A.M, Virgin, H.W, Fesik, S.W, Olejniczak, E.T.
登録日2001-10-03
公開日2002-04-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of a Bcl-2 homolog from Kaposi sarcoma virus.
Proc.Natl.Acad.Sci.USA, 99, 2002
1GNC
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STRUCTURE AND DYNAMICS OF THE HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR DETERMINED BY NMR SPECTROSCOPY. LOOP MOBILITY IN A FOUR-HELIX-BUNDLE PROTEIN
分子名称: GRANULOCYTE COLONY-STIMULATING FACTOR
著者Zink, T.W, Ross, A, Rudolph, R, Holak, T.A.
登録日1994-03-08
公開日1994-07-31
最終更新日2024-10-30
実験手法SOLUTION NMR
主引用文献Structure and dynamics of the human granulocyte colony-stimulating factor determined by NMR spectroscopy. Loop mobility in a four-helix-bundle protein.
Biochemistry, 33, 1994

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