5UYL
| 70S ribosome bound with cognate ternary complex base-paired to A site codon (Structure II) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A. | 登録日 | 2017-02-24 | 公開日 | 2017-06-14 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Ensemble cryo-EM elucidates the mechanism of translation fidelity. Nature, 546, 2017
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5DOY
| Crystal structure of the Thermus thermophilus 70S ribosome in complex with antibiotic Hygromycin A, mRNA and three tRNAs in the A, P and E sites at 2.6A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... | 著者 | Polikanov, Y.S, Starosta, A.L, Juette, M.F, Altman, R.B, Terry, D.S, Lu, W, Burnett, B.J, Dinos, G, Reynolds, K, Blanchard, S.C, Steitz, T.A, Wilson, D.N. | 登録日 | 2015-09-11 | 公開日 | 2015-12-30 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A. Mol.Cell, 58, 2015
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1FE0
| CRYSTAL STRUCTURE OF CADMIUM-HAH1 | 分子名称: | CADMIUM ION, COPPER TRANSPORT PROTEIN ATOX1, SULFATE ION, ... | 著者 | Wernimont, A.K, Huffman, D.L, Lamb, A.L, O'Halloran, T.V, Rosenzweig, A.C. | 登録日 | 2000-07-20 | 公開日 | 2001-01-20 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural basis for copper transfer by the metallochaperone for the Menkes/Wilson disease proteins. Nat.Struct.Biol., 7, 2000
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1KLK
| CRYSTAL STRUCTURE OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE TERNARY COMPLEX WITH PT653 AND NADPH | 分子名称: | Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE | 著者 | Cody, V, Galitsky, N, Luft, J.R, Pangborn, W, Rosowsky, A, Queener, S.F. | 登録日 | 2001-12-12 | 公開日 | 2002-12-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-based enzyme inhibitor design: modeling studies and crystal structure analysis of Pneumocystis carinii dihydrofolate reductase ternary complex with PT653 and NADPH. Acta Crystallogr.,Sect.D, 58, 2002
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5UYN
| 70S ribosome bound with near-cognate ternary complex not base-paired to A site codon (Structure I-nc) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A. | 登録日 | 2017-02-24 | 公開日 | 2017-06-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Ensemble cryo-EM elucidates the mechanism of translation fidelity Nature, 546, 2017
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3IWL
| Crystal structure of cisplatin bound to a human copper chaperone (monomer) | 分子名称: | 3,3',3''-phosphanetriyltripropanoic acid, Copper transport protein ATOX1, PLATINUM (II) ION, ... | 著者 | Boal, A.K, Rosenzweig, A.C. | 登録日 | 2009-09-02 | 公開日 | 2009-09-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structures of cisplatin bound to a human copper chaperone. J.Am.Chem.Soc., 131, 2009
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1FHI
| SUBSTRATE ANALOG (IB2) COMPLEX WITH THE FRAGILE HISTIDINE TRIAD PROTEIN, FHIT | 分子名称: | FRAGILE HISTIDINE TRIAD PROTEIN, P1-P2-METHYLENE-P3-THIO-DIADENOSINE TRIPHOSPHATE | 著者 | Pace, H.C, Garrison, P.N, Barnes, L.D, Draganescu, A, Rosler, A, Blackburn, G.M, Siprashvili, Z, Croce, C.M, Huebner, K, Brenner, C. | 登録日 | 1997-12-11 | 公開日 | 1998-06-17 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit. Proc.Natl.Acad.Sci.USA, 95, 1998
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1KX2
| Minimized average structure of a mono-heme ferrocytochrome c from Shewanella putrefaciens | 分子名称: | HEME C, mono-heme c-type cytochrome ScyA | 著者 | Bartalesi, I, Bertini, I, Hajieva, P, Rosato, A, Vasos, P.R. | 登録日 | 2002-01-30 | 公開日 | 2002-02-13 | 最終更新日 | 2024-10-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a monoheme ferrocytochrome c from Shewanella putrefaciens and structural analysis of sequence-similar proteins: functional implications. Biochemistry, 41, 2002
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1FZH
| METHANE MONOOXYGENASE HYDROXYLASE, FORM II PRESSURIZED WITH XENON GAS | 分子名称: | CALCIUM ION, FE (III) ION, METHANE MONOOXYGENASE COMPONENT A, ... | 著者 | Whittington, D.A, Rosenzweig, A.C, Frederick, C.A, Lippard, S.J. | 登録日 | 2000-10-03 | 公開日 | 2001-04-27 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Xenon and halogenated alkanes track putative substrate binding cavities in the soluble methane monooxygenase hydroxylase. Biochemistry, 40, 2001
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1LM0
| Solution structure and characterization of the heme chaperone CcmE | 分子名称: | cytochrome c maturation protein E | 著者 | Arnesano, F, Banci, L, Barker, P.D, Bertini, I, Rosato, A, Su, X.C, Viezzoli, M.S. | 登録日 | 2002-04-30 | 公開日 | 2002-12-25 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and characterization of the heme chaperone CcmE Biochemistry, 41, 2002
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3JC1
| Electron cryo-microscopy of the IST1-CHMP1B ESCRT-III copolymer | 分子名称: | Charged multivesicular body protein 1b, Increased Sodium Tolerance 1 (IST1) | 著者 | McCullough, J, Clippinger, A.K, Talledge, N, Skowyra, M.L, Saunders, M.G, Naismith, T.V, Colf, L.A, Afonine, P, Arthur, C, Sundquist, W.I, Hanson, P.I, Frost, A. | 登録日 | 2015-11-09 | 公開日 | 2015-12-16 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structure and membrane remodeling activity of ESCRT-III helical polymers. Science, 350, 2015
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4H1Q
| Crystal structure of mutant MMP-9 catalytic domain in complex with a twin inhibitor. | 分子名称: | CALCIUM ION, Matrix metalloproteinase-9, N-(4-{[(3R)-3-[(biphenyl-4-ylsulfonyl)(propan-2-yloxy)amino]-4-(hydroxyamino)-4-oxobutyl]amino}-4-oxobutyl)-N'-(4-{[(3S)-3-[(biphenyl-4-ylsulfonyl)(propan-2-yloxy)amino]-4-(hydroxyamino)-4-oxobutyl]amino}-4-oxobutyl)benzene-1,3-dicarboxamide, ... | 著者 | Stura, E.A, Vera, L, Cassar-Lajeunesse, E, Nuti, E, Catalani, M.P, Dive, V, Rossello, A. | 登録日 | 2012-09-11 | 公開日 | 2013-04-24 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Crystallization of bi-functional ligand protein complexes. J.Struct.Biol., 182, 2013
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3F91
| Structural Data for Human Active Site Mutant Enzyme Complexes | 分子名称: | 2,4-DIAMINO-5-[2-METHOXY-5-(4-CARBOXYBUTYLOXY)BENZYL]PYRIMIDINE, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Cody, V, Pace, J, Makin, J, Piraino, J, Queener, S.F, Rosowsky, A. | 登録日 | 2008-11-13 | 公開日 | 2009-08-18 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Correlations of Inhibitor Kinetics for Pneumocystis jirovecii and Human Dihydrofolate Reductase with Structural Data for Human Active Site Mutant Enzyme Complexes. Biochemistry, 48, 2009
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1YJT
| Solution structure of the Cu(I) form of the sixth soluble domain A69P mutant of Menkes protein | 分子名称: | COPPER (I) ION, Copper-transporting ATPase 1 | 著者 | Banci, L, Bertini, I, Cantini, F, Migliardi, M, Rosato, A, Wang, S. | 登録日 | 2005-01-15 | 公開日 | 2006-01-03 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | An atomic-level investigation of the disease-causing A629P mutant of the Menkes protein, ATP7A J.Mol.Biol., 352, 2005
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1YJV
| Solution structure of the Cu(I) form of the sixth soluble domain of Menkes protein | 分子名称: | COPPER (I) ION, Copper-transporting ATPase 1 | 著者 | Banci, L, Bertini, I, Cantini, F, Migliardi, M, Rosato, A, Wang, S. | 登録日 | 2005-01-15 | 公開日 | 2006-01-03 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | An atomic-level investigation of the disease-causing A629P mutant of the Menkes protein, ATP7A J.Mol.Biol., 352, 2005
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3F8Y
| Correlations of Human Dihydrofolate Reductase with Structural Data for Human Active Site Mutant Enzyme Complexes | 分子名称: | 2,4-DIAMINO-5-[2-METHOXY-5-(4-CARBOXYBUTYLOXY)BENZYL]PYRIMIDINE, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Cody, V, Pace, J, Makin, J, Piraino, J, Queener, S.F, Rosowsky, A. | 登録日 | 2008-11-13 | 公開日 | 2009-08-18 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Correlations of Inhibitor Kinetics for Pneumocystis jirovecii and Human Dihydrofolate Reductase with Structural Data for Human Active Site Mutant Enzyme Complexes. Biochemistry, 48, 2009
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4N59
| The Crystal Structure of Pectocin M2 at 2.3 Angstroms | 分子名称: | CHLORIDE ION, FE2/S2 (INORGANIC) CLUSTER, Pectocin M2, ... | 著者 | Zeth, K, Grinter, R, Roszak, A.W, Cogdell, R.J, Walker, D. | 登録日 | 2013-10-09 | 公開日 | 2014-06-04 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the atypical bacteriocin pectocin M2 implies a novel mechanism of protein uptake. Mol.Microbiol., 93, 2014
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1FZ8
| METHANE MONOOXYGENASE HYDROXYLASE, FORM II COCRYSTALLIZED WITH DIBROMOMETHANE | 分子名称: | CALCIUM ION, DIBROMOMETHANE, FE (III) ION, ... | 著者 | Whittington, D.A, Rosenzweig, A.C, Frederick, C.A, Lippard, S.J. | 登録日 | 2000-10-03 | 公開日 | 2001-04-27 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Xenon and halogenated alkanes track putative substrate binding cavities in the soluble methane monooxygenase hydroxylase. Biochemistry, 40, 2001
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1G5B
| BACTERIOPHAGE LAMBDA SER/THR PROTEIN PHOSPHATASE | 分子名称: | MANGANESE (II) ION, MERCURY (II) ION, SERINE/THREONINE PROTEIN PHOSPHATASE, ... | 著者 | Voegtli, W.C, White, D.J, Reiter, N.J, Rusnak, F, Rosenzweig, A.C. | 登録日 | 2000-10-31 | 公開日 | 2001-03-07 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structure of the bacteriophage lambda Ser/Thr protein phosphatase with sulfate ion bound in two coordination modes. Biochemistry, 39, 2000
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1JXN
| Crystal Structure of the Lectin I from Ulex europaeus in complex with the methyl glycoside of alpha-L-fucose | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, CALCIUM ION, MANGANESE (II) ION, ... | 著者 | Audette, G.F, Olson, D.J.H, Ross, A.R.S, Quail, J.W, Delbaere, L.T.J. | 登録日 | 2001-09-07 | 公開日 | 2002-12-06 | 最終更新日 | 2024-10-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Examination of the Structural Basis for O(H) Blood Group Specificity by Ulex europaeus Lectin I Can.J.Chem., 80, 2002
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1JGT
| CRYSTAL STRUCTURE OF BETA-LACTAM SYNTHETASE | 分子名称: | BETA-LACTAM SYNTHETASE, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, GLYCEROL, ... | 著者 | Miller, M.T, Bachmann, B.O, Townsend, C.A, Rosenzweig, A.C. | 登録日 | 2001-06-26 | 公開日 | 2001-12-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structure of beta-lactam synthetase reveals how to synthesize antibiotics instead of asparagine. Nat.Struct.Biol., 8, 2001
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4G0F
| Crystal structure of the complex of a human telomeric repeat G-quadruplex and N-methyl mesoporphyrin IX (P6) | 分子名称: | DNA (5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), N-METHYLMESOPORPHYRIN, POTASSIUM ION | 著者 | Nicoludis, J.M, Miller, S.T, Jeffrey, P, Lawton, T.J, Rosenzweig, A.C, Yatsunyk, L.A. | 登録日 | 2012-07-09 | 公開日 | 2012-12-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Optimized End-Stacking Provides Specificity of N-Methyl Mesoporphyrin IX for Human Telomeric G-Quadruplex DNA. J.Am.Chem.Soc., 134, 2012
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1FZ9
| Methane monooxygenase hydroxylase, form II cocrystallized with iodoethane | 分子名称: | CALCIUM ION, FE (III) ION, IODOETHANE, ... | 著者 | Whittington, D.A, Rosenzweig, A.C, Frederick, C.A, Lippard, S.J. | 登録日 | 2000-10-03 | 公開日 | 2001-04-27 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Xenon and halogenated alkanes track putative substrate binding cavities in the soluble methane monooxygenase hydroxylase. Biochemistry, 40, 2001
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1K3K
| Solution Structure of a Bcl-2 Homolog from Kaposi's Sarcoma Virus | 分子名称: | functional anti-apoptotic factor vBCL-2 homolog | 著者 | Huang, Q, Petros, A.M, Virgin, H.W, Fesik, S.W, Olejniczak, E.T. | 登録日 | 2001-10-03 | 公開日 | 2002-04-10 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a Bcl-2 homolog from Kaposi sarcoma virus. Proc.Natl.Acad.Sci.USA, 99, 2002
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1GNC
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