4H1Q

Crystal structure of mutant MMP-9 catalytic domain in complex with a twin inhibitor.

Summary for 4H1Q

Entry DOI	10.2210/pdb4h1q/pdb
Related	2OW1 4H2E 4H30 4H3X
Descriptor	Matrix metalloproteinase-9, ZINC ION, CALCIUM ION, ... (5 entities in total)
Functional Keywords	hydrolase/twin inhibitor, zincin-like, gelatinase, collagenase (catalytic domain), hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human) More
Cellular location	Secreted, extracellular space, extracellular matrix : P14780
Total number of polymer chains	2
Total formula weight	38638.48
Authors	Stura, E.A.,Vera, L.,Cassar-Lajeunesse, E.,Nuti, E.,Catalani, M.P.,Dive, V.,Rossello, A. (deposition date: 2012-09-11, release date: 2013-04-24, Last modification date: 2023-09-13)
Primary citation	Antoni, C.,Vera, L.,Devel, L.,Catalani, M.P.,Czarny, B.,Cassar-Lajeunesse, E.,Nuti, E.,Rossello, A.,Dive, V.,Stura, E.A. Crystallization of bi-functional ligand protein complexes. J.Struct.Biol., 182:246-254, 2013 Cited by PubMed: 23567804 DOI: 10.1016/j.jsb.2013.03.015 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.59 Å)

Structure validation