Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0031012 | cellular_component | extracellular matrix |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0031012 | cellular_component | extracellular matrix |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 301 |
| Chain | Residue |
| A | HIS226 |
| A | HIS230 |
| A | HIS236 |
| A | 0XX307 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 302 |
| Chain | Residue |
| A | HIS175 |
| A | ASP177 |
| A | HIS190 |
| A | HIS203 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 303 |
| Chain | Residue |
| A | GLY197 |
| A | GLN199 |
| A | ASP201 |
| A | HOH477 |
| A | HOH481 |
| A | ASP165 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 304 |
| Chain | Residue |
| A | ASP131 |
| A | ASP206 |
| A | GLU208 |
| A | HOH421 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 305 |
| Chain | Residue |
| A | ASP182 |
| A | GLY183 |
| A | ASP185 |
| A | LEU187 |
| A | ASP205 |
| A | GLU208 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 306 |
| Chain | Residue |
| A | SER149 |
| A | THR152 |
| A | LEU154 |
| A | HOH496 |
| site_id | AC7 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE 0XX A 307 |
| Chain | Residue |
| A | TYR179 |
| A | PRO180 |
| A | PHE181 |
| A | ASP182 |
| A | LEU187 |
| A | LEU188 |
| A | ALA189 |
| A | HIS190 |
| A | ALA191 |
| A | PHE192 |
| A | PRO193 |
| A | LEU222 |
| A | HIS226 |
| A | GLN227 |
| A | HIS230 |
| A | HIS236 |
| A | LEU243 |
| A | TYR245 |
| A | PRO246 |
| A | MET247 |
| A | TYR248 |
| A | ZN301 |
| A | HOH449 |
| A | HOH526 |
| B | PRO240 |
| B | GLU241 |
| B | TYR245 |
| B | PRO246 |
| B | ARG249 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 301 |
| Chain | Residue |
| B | HIS226 |
| B | HIS230 |
| B | HIS236 |
| B | 0XX306 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 302 |
| Chain | Residue |
| B | HIS175 |
| B | ASP177 |
| B | HIS190 |
| B | HIS203 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 303 |
| Chain | Residue |
| B | ASP165 |
| B | GLY197 |
| B | GLN199 |
| B | ASP201 |
| B | HOH487 |
| B | HOH489 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 304 |
| Chain | Residue |
| B | ASP131 |
| B | ASP206 |
| B | GLU208 |
| B | HOH517 |
| B | HOH518 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 305 |
| Chain | Residue |
| B | ASP182 |
| B | GLY183 |
| B | ASP185 |
| B | LEU187 |
| B | ASP205 |
| B | GLU208 |
| site_id | BC4 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE 0XX B 306 |
| Chain | Residue |
| B | HIS236 |
| B | LEU243 |
| B | TYR245 |
| B | PRO246 |
| B | MET247 |
| B | TYR248 |
| B | HIS266 |
| B | ZN301 |
| B | HOH432 |
| B | HOH433 |
| B | HOH446 |
| B | HOH483 |
| B | HOH526 |
| A | TYR245 |
| A | PRO246 |
| A | HOH523 |
| B | GLY112 |
| B | LEU187 |
| B | LEU188 |
| B | ALA189 |
| B | HIS190 |
| B | ALA191 |
| B | PRO193 |
| B | LEU222 |
| B | HIS226 |
| B | GLN227 |
| B | HIS230 |
| B | GLY233 |
| B | LEU234 |
| B | ASP235 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"12051944","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12051944","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12051944","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12077439","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
4H1Q
