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PDB: 776 件

8OQU
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Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with Fragment-M-92
分子名称: 3-hydroxyacyl-CoA dehydrogenase, 4-chloranylbenzenesulfonic acid, GLYCEROL, ...
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2023-04-12
公開日2024-01-24
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Crystallographic fragment binding studies of the Mycobacterium tuberculosis trifunctional enzyme suggest binding pockets for the tails of the acyl-CoA substrates at its active sites and a potential substrate channeling path between them
Biorxiv, 2024
5LOT
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BU of 5lot by Molmil
Crystal structure of SCP2 thiolase from Leishmania mexicana. Complex of the C123A mutant with acetyl-CoA.
分子名称: 3-ketoacyl-CoA thiolase-like protein, ACETYL COENZYME *A
著者Harijan, R.K, Kiema, T.-R, Wierenga, R.K.
登録日2016-08-09
公開日2017-01-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystallographic substrate binding studies of Leishmania mexicana SCP2-thiolase (type-2): unique features of oxyanion hole-1.
Protein Eng. Des. Sel., 30, 2017
6TIM
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BU of 6tim by Molmil
THE ADAPTABILITY OF THE ACTIVE SITE OF TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE AS OBSERVED IN THE CRYSTAL STRUCTURES OF THREE DIFFERENT COMPLEXES
分子名称: SN-GLYCEROL-3-PHOSPHATE, TRIOSEPHOSPHATE ISOMERASE
著者Noble, M.E.M, Wierenga, R.K, Hol, W.G.J.
登録日1991-04-23
公開日1992-10-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes.
Proteins, 10, 1991
6TNM
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BU of 6tnm by Molmil
E. coli aerobic trifunctional enzyme subunit-alpha
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Fatty acid oxidation complex subunit alpha, GLYCEROL, ...
著者Sah-Teli, S.K, Hynonen, M.J, Wierenga, R.K, Venkatesan, R.
登録日2019-12-09
公開日2020-03-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Insights into the stability and substrate specificity of the E. coli aerobic beta-oxidation trifunctional enzyme complex.
J.Struct.Biol., 210, 2020
5F0V
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BU of 5f0v by Molmil
X-ray crystal structure of a thiolase from Escherichia coli at 1.8 A resolution
分子名称: 1,2-ETHANEDIOL, Acetyl-CoA acetyltransferase
著者Ithayaraja, M, Neelanjana, J, Wierenga, R, Savithri, H.S, Murthy, M.R.N.
登録日2015-11-28
公開日2016-07-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a thiolase from Escherichia coli at 1.8 angstrom resolution.
Acta Crystallogr.,Sect.F, 72, 2016
5F38
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BU of 5f38 by Molmil
X-ray crystal structure of a thiolase from Escherichia coli at 1.8 A resolution
分子名称: 1,2-ETHANEDIOL, Acetyl-CoA acetyltransferase, COENZYME A, ...
著者Ithayaraja, M, Neelanjana, J, Wierenga, R, Savithri, H.S, Murthy, M.R.N.
登録日2015-12-02
公開日2016-07-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of a thiolase from Escherichia coli at 1.8 angstrom resolution.
Acta Crystallogr.,Sect.F, 72, 2016
8PJ0
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BU of 8pj0 by Molmil
Pseudomonas aeruginosa FabF C164A mutant in complex with N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-3-methylbutanamide
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, DIMETHYL SULFOXIDE, FORMIC ACID, ...
著者Georgiou, C, Brenk, R, Espeland, L.O.
登録日2023-06-22
公開日2024-02-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Design, quality and validation of the EU-OPENSCREEN fragment library poised to a high-throughput screening collection.
Rsc Med Chem, 15, 2024
7O1I
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Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme alpha-E141A mutant
分子名称: 3-hydroxyacyl-CoA dehydrogenase, COENZYME A, GLYCEROL, ...
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2021-03-29
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme.
J.Struct.Biol., 213, 2021
7O1G
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Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme alpha-E141A-H462A, beta-C92A mutant
分子名称: 3-hydroxyacyl-CoA dehydrogenase, Putative acyltransferase Rv0859, SULFATE ION
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2021-03-29
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme.
J.Struct.Biol., 213, 2021
7O1K
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BU of 7o1k by Molmil
Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme alpha-E141A, beta-C92A mutant
分子名称: 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, Putative acyltransferase Rv0859, ...
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2021-03-29
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme.
J.Struct.Biol., 213, 2021
7O4V
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Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with oxidized nicotinamide adenine dinucleotide
分子名称: 3-hydroxyacyl-CoA dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative acyltransferase Rv0859, ...
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2021-04-07
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme.
J.Struct.Biol., 213, 2021
7O1L
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BU of 7o1l by Molmil
Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme alpha-H462A mutant
分子名称: 3-hydroxyacyl-CoA dehydrogenase, COENZYME A, GLYCEROL, ...
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2021-03-29
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme.
J.Struct.Biol., 213, 2021
7O4U
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BU of 7o4u by Molmil
Structure of the alpha subunit of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with oxidized nicotinamide adenine dinucleotide
分子名称: 3-hydroxyacyl-CoA dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2021-04-07
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme.
J.Struct.Biol., 213, 2021
7O4Q
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BU of 7o4q by Molmil
Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme in space group C2221 (unliganded)
分子名称: 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, Putative acyltransferase Rv0859, ...
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2021-04-07
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme.
J.Struct.Biol., 213, 2021
7O1J
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BU of 7o1j by Molmil
Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme beta-C92A mutant
分子名称: 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, Putative acyltransferase Rv0859, ...
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2021-03-29
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme.
J.Struct.Biol., 213, 2021
7O4T
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BU of 7o4t by Molmil
Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme with Coenzyme A bound at the hydratase, thiolase active sites and possible additional binding site (CoA(ECH/HAD))
分子名称: 3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE, 3-hydroxyacyl-CoA dehydrogenase, COENZYME A, ...
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2021-04-07
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme.
J.Struct.Biol., 213, 2021
7O4R
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BU of 7o4r by Molmil
Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme with Coenzyme A bound at the thiolase active sites and additional binding site (CoA(HAD/KAT))
分子名称: 3-hydroxyacyl-CoA dehydrogenase, COENZYME A, GLYCEROL, ...
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2021-04-07
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme.
J.Struct.Biol., 213, 2021
7O1M
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BU of 7o1m by Molmil
Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme alpha-H462A, beta-C92A mutant
分子名称: 3-hydroxyacyl-CoA dehydrogenase, GLYCEROL, Putative acyltransferase Rv0859, ...
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2021-03-29
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme.
J.Struct.Biol., 213, 2021
7O4S
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BU of 7o4s by Molmil
Structure of Mycobacterium tuberculosis beta-oxidation trifunctional enzyme with Coenzyme A bound at the hydratase, thiolase active sites and additional binding site (CoA(ECH2))
分子名称: 3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE, 3-hydroxyacyl-CoA dehydrogenase, ADENOSINE-5'-DIPHOSPHATE, ...
著者Dalwani, S, Wierenga, R.K, Venkatesan, R.
登録日2021-04-07
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Substrate specificity and conformational flexibility properties of the Mycobacterium tuberculosis beta-oxidation trifunctional enzyme.
J.Struct.Biol., 213, 2021
7QH0
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BU of 7qh0 by Molmil
Apo structure of the Leishmania mexicana triose-phosphate isomerase (LmTIM), N11A-E65Q variant, open conformation
分子名称: CHLORIDE ION, SODIUM ION, Triosephosphate isomerase
著者Cordara, G, Wierenga, R.K.
登録日2021-12-10
公開日2022-10-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The Role of Asn11 in Catalysis by Triosephosphate Isomerase.
Biochemistry, 62, 2023
5HUT
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Structure of Candida albicans trehalose-6-phosphate synthase in complex with UDP-glucose
分子名称: Alpha,alpha-trehalose-phosphate synthase [UDP-forming], PENTAETHYLENE GLYCOL, SODIUM ION, ...
著者Miao, Y, Brennan, R.G.
登録日2016-01-27
公開日2017-05-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design.
MBio, 8, 2017
1E21
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BU of 1e21 by Molmil
Ribonuclease 1 des1-7 Crystal Structure at 1.9A
分子名称: RIBONUCLEASE 1
著者Pous, J, Mallorqui-Fernandez, G, Peracaula, R, Terzyan, S.S, Futami, J, Tada, H, Yamada, H, Seno, M, De Llorens, R, Gomis-Ruth, F.X, Coll, M.
登録日2000-05-15
公開日2001-05-03
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Three-Dimensional Crystal Structure of Human Rnase 1Dn7 at 1.9A Resolution
Acta Crystallogr.,Sect.D, 57, 2001
1DYT
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BU of 1dyt by Molmil
X-ray crystal structure of ECP (RNase 3) at 1.75 A
分子名称: CITRIC ACID, EOSINOPHIL CATIONIC PROTEIN, FE (III) ION
著者Mallorqui-Fernandez, G, Pous, J, Peracaula, R, Maeda, T, Tada, H, Yamada, H, Seno, M, De Llorens, R, Gomis-Rueth, F.X, Coll, M.
登録日2000-02-08
公開日2001-02-08
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Three-Dimensional Crystal Structure of Human Eosinophil Cationic Protein (Rnase 3) at 1.75 A Resolution.
J.Mol.Biol., 300, 2000
6WMT
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BU of 6wmt by Molmil
F. tularensis RNAPs70-(MglA-SspA)-ppGpp-PigR-iglA DNA complex
分子名称: DNA NT-strand, DNA NT-strand downstream, DNA T-strand, ...
著者Travis, B.A, Brennan, R.G, Schumacher, M.A.
登録日2020-04-21
公開日2020-11-11
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.43 Å)
主引用文献Structural Basis for Virulence Activation of Francisella tularensis.
Mol.Cell, 81, 2021
5DXN
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Structure of Aspergillus fumigatus trehalose-6-phosphate phosphatase crystal form 2
分子名称: MAGNESIUM ION, trehalose-6-phosphate phosphatase
著者Miao, Y, Brennan, R.G.
登録日2015-09-23
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis.
Proc.Natl.Acad.Sci.USA, 113, 2016

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件を2024-06-19に公開中

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