4CCS
 
 | | The structure of CbiX, the terminal Enzyme for Biosynthesis of Siroheme in Denitrifying Bacteria | | Descriptor: | 1,2-ETHANEDIOL, CBIX, D-MALATE, ... | | Authors: | Bali, S, Rollauer, S.E, Roversi, P, Raux-Deery, E, Lea, S.M, Warren, M.J, Ferguson, S.J. | | Deposit date: | 2013-10-25 | | Release date: | 2014-04-09 | | Last modified: | 2015-09-23 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Identification and Characterization of the 'Missing' Terminal Enzyme for Siroheme Biosynthesis in Alpha-Proteobacteria.
Mol.Microbiol., 92, 2014
|
|
4BXT
 | |
4D1W
 | | A H224Y mutant for VIM-7 from Pseudomonas aeruginosa | | Descriptor: | METALLO-B-LACTAMASE, ZINC ION | | Authors: | Leiros, H.-K.S, Skagseth, S, Edvardsen, K.S.W, Lorentzen, M.S, Bjerga, G.E.K, Leiros, I, Samuelsen, O. | | Deposit date: | 2014-05-05 | | Release date: | 2014-06-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7.
Antimicrob.Agents Chemother., 58, 2014
|
|
4D1U
 | | A D120A mutant of VIM-7 from Pseudomonas aeruginosa | | Descriptor: | METALLO-B-LACTAMASE, ZINC ION | | Authors: | Leiros, H.-K.S, Skagseth, S, Edvardsen, K.S.W, Lorentzen, M.S, Bjerga, G.E.K, Leiros, I, Samuelsen, O. | | Deposit date: | 2014-05-05 | | Release date: | 2014-06-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7.
Antimicrob.Agents Chemother., 58, 2014
|
|
3QPB
 | | Crystal Structure of Streptococcus Pyogenes Uridine Phosphorylase Reveals a Subclass of the NP-I Superfamily | | Descriptor: | 1-O-phosphono-alpha-D-ribofuranose, URACIL, Uridine phosphorylase | | Authors: | Tran, T.H, Christoffersen, S, Parker, W.B, Piskur, J, Serra, I, Terreni, M, Ealick, S.E. | | Deposit date: | 2011-02-11 | | Release date: | 2011-08-24 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | The Crystal Structure of Streptococcus pyogenes Uridine Phosphorylase Reveals a Distinct Subfamily of Nucleoside Phosphorylases.
Biochemistry, 50, 2011
|
|
3EID
 | | CDK2/CyclinA complexed with a pyrazolopyridazine inhibitor | | Descriptor: | (2S)-1-(dimethylamino)-3-(4-{[4-(6-morpholin-4-ylpyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-yl]amino}phenoxy)propan-2-ol, Cell division protein kinase 2, Cyclin-A2 | | Authors: | Steven, K, Reno, M, Alberti, J, Price, D, Kane-Carson, L, Knick, V, Shewchuk, L, Hassell, A, Veal, J, Peel, M. | | Deposit date: | 2008-09-15 | | Release date: | 2008-10-21 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Synthesis and evaluation of pyrazolo[1,5-b]pyridazines as selective cyclin dependent kinase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
|
|
4KVG
 | | Crystal structure of RIAM RA-PH domains in complex with GTP bound Rap1 | | Descriptor: | 1,2-ETHANEDIOL, Amyloid beta A4 precursor protein-binding family B member 1-interacting protein, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Zhang, H, Chang, Y.E, Brennan, M.L, Wu, J. | | Deposit date: | 2013-05-22 | | Release date: | 2014-03-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | The structure of Rap1 in complex with RIAM reveals specificity determinants and recruitment mechanism.
J Mol Cell Biol, 6, 2014
|
|
5MBL
 | |
4D1T
 | | High resolution structure of native tVIM-7 from Pseudomonas aeruginosa | | Descriptor: | METALLO-B-LACTAMASE, ZINC ION | | Authors: | Leiros, H.-K.S, Skagseth, S, Edvardsen, K.S.W, Lorentzen, M.S, Bjerga, G.E.K, Leiros, I, Samuelsen, O. | | Deposit date: | 2014-05-05 | | Release date: | 2014-06-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7.
Antimicrob.Agents Chemother., 58, 2014
|
|
3EJ1
 | | CDK2/CyclinA complexed with a pyrazolopyridazine inhibitor | | Descriptor: | Cell division protein kinase 2, Cyclin-A2, N-cyclopropyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amine | | Authors: | Stevens, K, Reno, M, Alberti, J, Price, D, Kane-Carson, L, Knick, V, Shewchuk, L, Hassell, A, Veal, J, Peel, M. | | Deposit date: | 2008-09-17 | | Release date: | 2008-10-21 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.22 Å) | | Cite: | Synthesis and evaluation of pyrazolo[1,5-b]pyridazines as selective cyclin dependent kinase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
|
|
7MQS
 | | The insulin receptor ectodomain in complex with three venom hybrid insulin molecules - asymmetric conformation | | Descriptor: | Insulin A chain, Insulin B chain, Isoform Short of Insulin receptor | | Authors: | Blakely, A.D, Xiong, X, Kim, J.H, Menting, J, Schafer, I.B, Schubert, H.L, Agrawal, R, Gutmann, T, Delaine, C, Zhang, Y, Artik, G.O, Merriman, A, Eckert, D, Lawrence, M.C, Coskun, U, Fisher, S.J, Forbes, B.E, Safavi-Hemami, H, Hill, C.P, Chou, D.H.C. | | Deposit date: | 2021-05-06 | | Release date: | 2022-03-16 | | Last modified: | 2023-03-29 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Symmetric and asymmetric receptor conformation continuum induced by a new insulin.
Nat.Chem.Biol., 18, 2022
|
|
3CB0
 | | CobR | | Descriptor: | 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE, FLAVIN MONONUCLEOTIDE | | Authors: | Lawrence, A.D, Warren, M.J, Pickersgill, R.W. | | Deposit date: | 2008-02-21 | | Release date: | 2008-03-11 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Identification, characterization, and structure/function analysis of a corrin reductase involved in adenosylcobalamin biosynthesis
J.Biol.Chem., 283, 2008
|
|
3ZTT
 | | Crystal structure of pneumococcal surface antigen PsaA with manganese | | Descriptor: | MANGANESE (II) ION, MANGANESE ABC TRANSPORTER SUBSTRATE-BINDING LIPOPROTEIN | | Authors: | McDevitt, C.A, Ogunniyi, A.D, Valkov, E, Lawrence, M.C, Kobe, B, McEwan, A.G, Paton, J.C. | | Deposit date: | 2011-07-12 | | Release date: | 2011-12-07 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A molecular mechanism for bacterial susceptibility to zinc.
PLoS Pathog., 7, 2011
|
|
2YG1
 | | APO STRUCTURE OF CELLOBIOHYDROLASE 1 (CEL7A) FROM HETEROBASIDION ANNOSUM | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CELLULOSE 1,4-BETA-CELLOBIOSIDASE, MAGNESIUM ION | | Authors: | Haddad-Momeni, M, Hansson, H, Mikkelsen, N.E, Wang, X, Svedberg, J, Sandgren, M, Stahlberg, J. | | Deposit date: | 2011-04-11 | | Release date: | 2012-04-25 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural, Biochemical, and Computational Characterization of the Glycoside Hydrolase Family 7 Cellobiohydrolase of the Tree-Killing Fungus Heterobasidion Irregulare.
J.Biol.Chem., 288, 2013
|
|
3PAC
 | |
1O84
 | | Crystal Structure of Bacteriocin AS-48. N-decyl-beta-D-maltoside Bound. | | Descriptor: | DECANE, GLYCEROL, PEPTIDE ANTIBIOTIC AS-48, ... | | Authors: | Sanchez-Barrena, M.J, Martinez-Ripoll, M, Galvez, A, Valdivia, E, Maqueda, M, Cruz, V, Albert, A. | | Deposit date: | 2002-11-25 | | Release date: | 2003-11-20 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structure of Bacteriocin as-48: From Soluble State to Membrane Bound State
J.Mol.Biol., 334, 2003
|
|
2WNE
 | | Mutant Laminarinase 16A cyclizes laminariheptaose | | Descriptor: | PUTATIVE LAMINARINASE, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-alpha-D-glucopyranose | | Authors: | Vasur, J, Kawai, R, Andersson, E, Widmalm, G, Jonsson, K.H.M, Hansson, H, Engstrom, A, Einarsson, E, Forsberg, Z, Igarashi, K, Sandgren, M, Samejima, M, Stahlberg, J. | | Deposit date: | 2009-07-09 | | Release date: | 2010-01-26 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.124 Å) | | Cite: | Synthesis of Cyclic Beta-Glucan Using Laminarinase 16A Glycosynthase Mutant from the Basidiomycete Phanerochaete Chrysosporium.
J.Am.Chem.Soc., 132, 2010
|
|
1O83
 | | Crystal Structure of Bacteriocin AS-48 at pH 7.5, phosphate bound. Crystal form I | | Descriptor: | GLYCEROL, PEPTIDE ANTIBIOTIC AS-48, PHOSPHATE ION | | Authors: | Sanchez-Barrena, M.J, Martinez-Ripoll, M, Galvez, A, Valdivia, E, Maqueda, M, Cruz, V, Albert, A. | | Deposit date: | 2002-11-25 | | Release date: | 2003-11-20 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Structure of Bacteriocin as-48: From Soluble State to Membrane Bound State
J.Mol.Biol., 334, 2003
|
|
1O82
 | | X-RAY STRUCTURE OF BACTERIOCIN AS-48 AT PH 4.5. SULPHATE BOUND FORM | | Descriptor: | GLYCEROL, PEPTIDE ANTIBIOTIC AS-48, SULFATE ION | | Authors: | Sanchez-Barrena, M.J, Martinez-Ripoll, M, Galvez, A, Martinez-Bueno, M, Maqueda, M, Cruz, V, Albert, A. | | Deposit date: | 2002-11-22 | | Release date: | 2003-11-20 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.46 Å) | | Cite: | Structure of Bacteriocin as-48: From Soluble State to Membrane Bound State
J.Mol.Biol., 334, 2003
|
|
2XWS
 | | ANAEROBIC COBALT CHELATASE (CbiX) FROM ARCHAEOGLOBUS FULGIDUS | | Descriptor: | SIROHYDROCHLORIN COBALTOCHELATASE | | Authors: | Romao, C.V, Ladakis, D, Lobo, S.A.L, Carrondo, M.A, Brindley, A.A, Deery, E, Matias, P.M, Pickersgill, R.W, Saraiva, L.M, Warren, M.J. | | Deposit date: | 2010-11-04 | | Release date: | 2010-12-22 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Evolution in a Family of Chelatases Facilitated by the Introduction of Active Site Asymmetry and Protein Oligomerization.
Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
2RLJ
 | | NMR Structure of Ebola fusion peptide in SDS micelles at pH 7 | | Descriptor: | Envelope glycoprotein | | Authors: | Freitas, M.S, Gaspar, L.P, Lorenzoni, M, Almeida, F.C, Tinoco, L.W, Almeida, M.S, Maia, L.F, Degreve, L, Valente, A.P, Silva, J.L. | | Deposit date: | 2007-07-05 | | Release date: | 2007-08-07 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structure of the Ebola fusion peptide in a membrane-mimetic environment and the interaction with lipid rafts.
J.Biol.Chem., 282, 2007
|
|
1F6P
 | |
1F5Z
 | |
2VN4
 | | Glycoside Hydrolase Family 15 Glucoamylase from Hypocrea jecorina | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Bott, R, Sandgren, M, Hansson, H. | | Deposit date: | 2008-01-30 | | Release date: | 2008-05-20 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Three-Dimensional Structure of an Intact Glycoside Hydrolase Family 15 Glucoamylase from Hypocrea Jecorina.
Biochemistry, 47, 2008
|
|
1FLA
 | | CLOSTRIDIUM BEIJERINCKII FLAVODOXIN MUTANT: G57D REDUCED | | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN | | Authors: | Ludwig, M.L, Pattridge, K.A, Metzger, A.L, Dixon, M.M, Eren, M, Feng, Y, Swenson, R. | | Deposit date: | 1996-12-18 | | Release date: | 1997-03-12 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Control of oxidation-reduction potentials in flavodoxin from Clostridium beijerinckii: the role of conformation changes.
Biochemistry, 36, 1997
|
|
