3QPB

Crystal Structure of Streptococcus Pyogenes Uridine Phosphorylase Reveals a Subclass of the NP-I Superfamily

Summary for 3QPB

• Entry DOI: 10.2210/pdb3qpb/pdb
• Descriptor: Uridine phosphorylase, 1-O-phosphono-alpha-D-ribofuranose, URACIL, ... (4 entities in total)
• Functional Keywords: hexamer, np-i superfamily, pyrimidine salvage pathway, uridine phosphorylase, transition state, transferase
• Biological source: Streptococcus pyogenes serotype M6
• Total number of polymer chains: 18
• Total formula weight: 556157.11

Authors

Tran, T.H.,Christoffersen, S.,Parker, W.B.,Piskur, J.,Serra, I.,Terreni, M.,Ealick, S.E. (deposition date: 2011-02-11, release date: 2011-08-24, Last modification date: 2024-02-21)

• Primary citation: Tran, T.H.,Christoffersen, S.,Allan, P.W.,Parker, W.B.,Serra, I.,Terreni, M.,Ealick, S.E.; The Crystal Structure of Streptococcus pyogenes Uridine Phosphorylase Reveals a Distinct Subfamily of Nucleoside Phosphorylases.; Biochemistry, 50:6549-6558, 2011; PubMed: 21707079; DOI: 10.1021/bi200707z

Experimental method

X-RAY DIFFRACTION (1.82 Å)