3QPB

Crystal Structure of Streptococcus Pyogenes Uridine Phosphorylase Reveals a Subclass of the NP-I Superfamily

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Uridine phosphorylase	polymer	282	30555.4	18	UniProt (Q5XA29)	Streptococcus pyogenes serotype M6
2	AA, AB, CA, EA, GA... (E, R, F, G, H...)	1-O-phosphono-alpha-D-ribofuranose	non-polymer		230.1	18	Chemie (R1P)
3	BA, BB, DA, FA, HA... (E, R, F, G, H...)	URACIL	non-polymer		112.1	18	Chemie (URA)
4	CB, DB, EB, FB, GB... (A, B, C, D, E...)	water	water		18.0	2979	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R: 1 - 259 (UniProt: Q5XA29)

PDB	External Database	Details
Met -22	-	expression tag
Gly -21	-	expression tag
Ser -20	-	expression tag
Asp -19	-	expression tag
Lys -18	-	expression tag
Ile -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	18
	Total formula weight	549997.6
Non-Polymers*	Number of molecules	36
	Total formula weight	6159.5
All*	Total formula weight	556157.1

*Water molecules are not included.