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PDB: 160 件

7RQ8
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Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with iboxamycin, mRNA, deacylated A- and E-site tRNAs, and aminoacylated P-site tRNA at 2.50A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Mitcheltree, M.J, Pisipati, A, Syroegin, E.A, Silvestre, K.J, Klepacki, D, Mason, J.D, Terwilliger, D.W, Testolin, G, Pote, A.R, Wu, K.J.Y, Ladley, R.P, Chatman, K, Mankin, A.S, Polikanov, Y.S, Myers, A.G.
登録日2021-08-06
公開日2021-10-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A synthetic antibiotic class overcoming bacterial multidrug resistance.
Nature, 599, 2021
7RQ9
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Crystal structure of the A2058-dimethylated Thermus thermophilus 70S ribosome in complex with iboxamycin, mRNA, deacylated A- and E-site tRNAs, and aminoacylated P-site tRNA at 2.60A resolution
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Mitcheltree, M.J, Pisipati, A, Syroegin, E.A, Silvestre, K.J, Klepacki, D, Mason, J.D, Terwilliger, D.W, Testolin, G, Pote, A.R, Wu, K.J.Y, Ladley, R.P, Chatman, K, Mankin, A.S, Polikanov, Y.S, Myers, A.G.
登録日2021-08-06
公開日2021-10-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A synthetic antibiotic class overcoming bacterial multidrug resistance.
Nature, 599, 2021
8OMW
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Crystal structure of the titin domain Fn3-20
分子名称: CHLORIDE ION, Titin
著者Rees, M, Gautel, M.
登録日2023-03-31
公開日2023-08-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation.
J.Struct.Biol., 215, 2023
8OIY
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Crystal structure of the R15908H missense variant of titin domain Fn3-3
分子名称: Titin
著者Rees, M, Gautel, M.
登録日2023-03-23
公開日2023-08-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation.
J.Struct.Biol., 215, 2023
8OQ9
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Crystal structure of the titin domain Fn3-56
分子名称: CHLORIDE ION, Titin, ZINC ION
著者Rees, M, Gautel, M.
登録日2023-04-11
公開日2023-08-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation.
J.Struct.Biol., 215, 2023
8ORL
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Crystal structure of the S23226G missense variant of titin domain Fn3-56
分子名称: CHLORIDE ION, Titin, ZINC ION
著者Rees, M, Gautel, M.
登録日2023-04-14
公開日2023-08-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation.
J.Struct.Biol., 215, 2023
4O00
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Crystal structure of the Titin A-band domain A3
分子名称: Titin
著者Rees, M.J, Gautel, M.
登録日2013-12-13
公開日2014-12-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.853 Å)
主引用文献Crystal structure of the Titin A-band domain A3
To be Published
4AQP
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The structure of the AXH domain of ataxin-1.
分子名称: ATAXIN-1, DI(HYDROXYETHYL)ETHER, SODIUM ION
著者Rees, M, Chen, Y.W, de Chiara, C, Pastore, A.
登録日2012-04-19
公開日2013-03-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.452 Å)
主引用文献Self-Assembly and Conformational Heterogeneity of the Axh Domain of Ataxin-1: An Unusual Example of a Chameleon Fold
Biophys.J., 104, 2013
4APT
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The structure of the AXH domain of ataxin-1.
分子名称: ATAXIN-1, SODIUM ION
著者Rees, M, Chen, Y.W, de Chiara, C, Pastore, A.
登録日2012-04-05
公開日2013-03-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Self-Assembly and Conformational Heterogeneity of the Axh Domain of Ataxin-1: An Unusual Example of a Chameleon Fold
Biophys.J., 104, 2013
6MXT
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Crystal structure of human beta2 adrenergic receptor bound to salmeterol and Nb71
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Endolysin, ...
著者Masureel, M, Zou, Y, Picard, L.P, van der Westhuizen, E, Mahoney, J.P, Rodrigues, J.P.G.L.M, Mildorf, T.J, Dror, R.O, Shaw, D.E, Bouvier, M, Pardon, E, Steyaert, J, Sunahara, R.K, Weis, W.I, Zhang, C, Kobilka, B.K.
登録日2018-10-31
公開日2018-11-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.95934224 Å)
主引用文献Structural insights into binding specificity, efficacy and bias of a beta2AR partial agonist.
Nat. Chem. Biol., 14, 2018
6RI7
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Cryo-EM structure of E. coli RNA polymerase elongation complex bound to GreB transcription factor
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Abdelkareem, M, Saint-Andre, C, Takacs, M, Papai, G, Crucifix, C, Guo, X, Ortiz, J, Weixlbaumer, A.
登録日2019-04-23
公開日2019-07-03
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural Basis of Transcription: RNA Polymerase Backtracking and Its Reactivation.
Mol.Cell, 75, 2019
6RIN
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BU of 6rin by Molmil
Cryo-EM structure of E. coli RNA polymerase backtracked elongation complex bound to GreB transcription factor
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Abdelkareem, M, Saint-Andre, C, Takacs, M, Papai, G, Crucifix, C, Guo, X, Ortiz, J, Weixlbaumer, A.
登録日2019-04-24
公開日2019-07-03
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural Basis of Transcription: RNA Polymerase Backtracking and Its Reactivation.
Mol.Cell, 75, 2019
6RH3
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Cryo-EM structure of E. coli RNA polymerase elongation complex bound to CTP substrate
分子名称: CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Abdelkareem, M, Saint-Andre, C, Takacs, M, Papai, G, Crucifix, C, Guo, X, Ortiz, J, Weixlbaumer, A.
登録日2019-04-18
公開日2019-07-03
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural Basis of Transcription: RNA Polymerase Backtracking and Its Reactivation.
Mol.Cell, 75, 2019
6RIP
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Cryo-EM structure of E. coli RNA polymerase backtracked elongation complex in swiveled state
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Abdelkareem, M, Saint-Andre, C, Takacs, M, Papai, G, Crucifix, C, Guo, X, Ortiz, J, Weixlbaumer, A.
登録日2019-04-24
公開日2019-07-03
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural Basis of Transcription: RNA Polymerase Backtracking and Its Reactivation.
Mol.Cell, 75, 2019
6RI9
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Cryo-EM structure of E. coli RNA polymerase backtracked elongation complex in non-swiveled state
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Abdelkareem, M, Saint-Andre, C, Takacs, M, Papai, G, Crucifix, C, Guo, X, Ortiz, J, Weixlbaumer, A.
登録日2019-04-23
公開日2019-07-03
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural Basis of Transcription: RNA Polymerase Backtracking and Its Reactivation.
Mol.Cell, 75, 2019
3O2D
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BU of 3o2d by Molmil
Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody
分子名称: T-cell surface glycoprotein CD4, ibalizumab heavy chain, ibalizumab light chain
著者Freeman, M.M, Seaman, M.S, Rits-Volloch, S, Hong, X, Ho, D.D, Chen, B.
登録日2010-07-22
公開日2010-12-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Crystal Structure of HIV-1 Primary Receptor CD4 in Complex with a Potent Antiviral Antibody.
Structure, 18, 2010
3PNI
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BU of 3pni by Molmil
Crystal structure of D14C [3Fe-4S] Pyrococcus furiosus ferredoxin
分子名称: COBALT (II) ION, FE3-S4 CLUSTER, Ferredoxin
著者Loevgreen, M.N, Christensen, H.E.M, Harris, P.
登録日2010-11-19
公開日2011-04-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of the all cysteinyl coordinated D14C variant of Pyrococcus furiosus ferredoxin: [4Fe-4S] <-> [3Fe-4S] cluster conversion
J.Biol.Inorg.Chem., 16, 2011
4LV5
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BU of 4lv5 by Molmil
Murine IRGa6 bound to Toxoplasma ROP5B, a pseudokinase GDI
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, BETA-MERCAPTOETHANOL, ...
著者Reese, M.L, Boothroyd, J.C.
登録日2013-07-25
公開日2013-09-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Murine IRGa6 bound to Toxoplasma ROP5B, a pseudokinase GDI
To be Published
4LV8
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Murine IRGa6 bound to Toxoplasma ROP5C, a pseudokinase GDI
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, ...
著者Reese, M.L, Boothroyd, J.C.
登録日2013-07-26
公開日2013-09-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Murine IRGa6 bound to Toxoplasma ROP5C, a pseudokinase GDI
To be Published
3Q5Z
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Crystal structure of virulent allele ROP5B pseudokinase domain
分子名称: 1,2-ETHANEDIOL, ROP5B
著者Reese, M.L, Boothroyd, J.C.
登録日2010-12-30
公開日2011-02-23
最終更新日2012-02-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A conserved non-canonical motif in the pseudoactive site of the ROP5 pseudokinase domain mediates its effect on Toxoplasma virulence.
J.Biol.Chem., 286, 2011
4A6A
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A115V variant of dCTP deaminase-dUTPase from Mycobacterium tuberculosis in complex with dTTP
分子名称: DEOXYCYTIDINE TRIPHOSPHATE DEAMINASE, MAGNESIUM ION, THYMIDINE-5'-TRIPHOSPHATE
著者Lovgreen, M.N, Ucar, E, Willemoes, M, Harris, P.
登録日2011-11-01
公開日2012-10-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Dttp Inhibition of the Bifunctional Dctp Deaminase- Dutpase from Mycobacterium Tuberculosis is Ph Dependent: Kinetic Analyses and Crystal Structure of A115V Variant
To be Published
3Q60
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Crystal structure of virulent allele ROP5B pseudokinase domain bound to ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, MALONATE ION, ...
著者Reese, M.L, Boothroyd, J.C.
登録日2010-12-30
公開日2011-02-23
最終更新日2012-02-22
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献A conserved non-canonical motif in the pseudoactive site of the ROP5 pseudokinase domain mediates its effect on Toxoplasma virulence.
J.Biol.Chem., 286, 2011
2PYY
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Crystal Structure of the GluR0 ligand-binding core from Nostoc punctiforme in complex with (L)-glutamate
分子名称: GLUTAMIC ACID, Ionotropic glutamate receptor bacterial homologue
著者Lee, J.H, Kang, G.B, Lim, H.-H, Ree, M, Park, C.-S, Eom, S.H.
登録日2007-05-17
公開日2008-01-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the GluR0 ligand-binding core from Nostoc punctiforme in complex with L-glutamate: structural dissection of the ligand interaction and subunit interface.
J.Mol.Biol., 376, 2008
3G04
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Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HUMAN THYROID STIMULATING AUTOANTIBODY M22 HEAVY CHAIN, HUMAN THYROID STIMULATING AUTOANTIBODY M22 LIGHT CHAIN, ...
著者Sanders, J, Chirgadze, D.Y, Sanders, P, Baker, S, Sullivan, A, Bhardwaja, A, Bolton, J, Reeve, M, Nakatake, N, Evans, M, Richards, T, Powell, M, Miguel, R.N, Blundell, T.L, Furmaniak, J, Smith, B.R.
登録日2009-01-27
公開日2009-08-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of the TSH receptor in complex with a thyroid-stimulating autoantibody
Thyroid, 17, 2007
2PPY
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Crystal structure of Enoyl-CoA hydrates (gk_1992) from Geobacillus Kaustophilus HTA426
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Enoyl-CoA hydratase
著者Kanaujia, S.P, Jeyakanthan, J, Kavyashree, M, Sekar, K, Ebihara, A, Kuramitsu, S, Shinkai, A, Shiro, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2007-05-01
公開日2008-05-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Crystal structure of Enoyl-CoA hydrates (gk_1992) from Geobacillus Kaustophilus HTA426
To be Published

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件を2024-07-31に公開中

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