1OC0
 
 | | plasminogen activator inhibitor-1 complex with somatomedin B domain of vitronectin | | 分子名称: | PLASMINOGEN ACTIVATOR INHIBITOR-1, VITRONECTIN | | 著者 | Read, R.J, Zhou, A, Huntington, J.A, Pannu, N.S, Carrell, R.W. | | 登録日 | 2003-02-03 | | 公開日 | 2003-06-19 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | How Vitronectin Binds Pai-1 to Modulate Fibrinolysis and Cell Migration
Nat.Struct.Biol., 10, 2003
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1SGT
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3SGB
 | | STRUCTURE OF THE COMPLEX OF STREPTOMYCES GRISEUS PROTEASE B AND THE THIRD DOMAIN OF THE TURKEY OVOMUCOID INHIBITOR AT 1.8 ANGSTROMS RESOLUTION | | 分子名称: | PROTEINASE B (SGPB), TURKEY OVOMUCOID INHIBITOR (OMTKY3) | | 著者 | Read, R.J, Fujinaga, M, Sielecki, A.R, James, M.N.G. | | 登録日 | 1983-01-21 | | 公開日 | 1983-07-12 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of the complex of Streptomyces griseus protease B and the third domain of the turkey ovomucoid inhibitor at 1.8-A resolution.
Biochemistry, 22, 1983
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4V0V
 | | The crystal structure of mouse PP1G in complex with truncated human PPP1R15B (631-660) | | 分子名称: | MANGANESE (II) ION, PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 15B, SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT, ... | | 著者 | Chen, R, Yan, Y, Casado, A.C, Ron, D, Read, R.J. | | 登録日 | 2014-09-18 | | 公開日 | 2015-03-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | G-actin provides substrate-specificity to eukaryotic initiation factor 2 alpha holophosphatases.
Elife, 4, 2015
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8CKP
 | | X-ray structure of the crystallization-prone form of subfamily III haloalkane dehalogenase DhmeA from Haloferax mediterranei | | 分子名称: | Alpha/beta fold hydrolase, CHLORIDE ION | | 著者 | Marek, M, Chmelova, K, Schenkmayerova, A, Croll, T, Read, R.J, Diederichs, K. | | 登録日 | 2023-02-16 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | | 主引用文献 | Multimeric structure of a subfamily III haloalkane dehalogenase-like enzyme solved by combination of cryo-EM and x-ray crystallography.
Protein Sci., 32, 2023
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6EOE
 | | Crystal structure of AMPylated GRP78 with nucleotide | | 分子名称: | 78 kDa glucose-regulated protein, ADENOSINE-5'-DIPHOSPHATE, CITRATE ANION, ... | | 著者 | Yan, Y, Preissler, S, Ron, D, Read, R.J. | | 登録日 | 2017-10-09 | | 公開日 | 2017-11-01 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation.
Elife, 6, 2017
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6EOB
 | | Crystal structure of AMPylated GRP78 in apo form (Crystal form 1) | | 分子名称: | 78 kDa glucose-regulated protein, PHOSPHATE ION | | 著者 | Yan, Y, Preissler, S, Ron, D, Read, R.J. | | 登録日 | 2017-10-09 | | 公開日 | 2017-11-01 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation.
Elife, 6, 2017
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6RPX
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4V0U
 | | The crystal structure of ternary PP1G-PPP1R15B and G-actin complex | | 分子名称: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Chen, R, Yan, Y, Casado, A.C, Ron, D, Read, R.J. | | 登録日 | 2014-09-18 | | 公開日 | 2015-03-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (7.88 Å) | | 主引用文献 | G-actin provides substrate-specificity to eukaryotic initiation factor 2 alpha holophosphatases.
Elife, 4, 2015
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4V0W
 | | The crystal structure of mouse PP1G in complex with truncated human PPP1R15B (631-669) | | 分子名称: | MANGANESE (II) ION, PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 15B, SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT | | 著者 | Chen, R, Yan, Y, Casado, A.C, Ron, D, Read, R.J. | | 登録日 | 2014-09-18 | | 公開日 | 2015-03-25 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | G-actin provides substrate-specificity to eukaryotic initiation factor 2 alpha holophosphatases.
Elife, 4, 2015
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4Z9G
 | | Crystal structure of human corticotropin-releasing factor receptor 1 (CRF1R) in complex with the antagonist CP-376395 in a hexagonal setting with translational non-crystallographic symmetry | | 分子名称: | 3,6-dimethyl-N-(pentan-3-yl)-2-(2,4,6-trimethylphenoxy)pyridin-4-amine, Corticotropin-releasing factor receptor 1,Lysozyme,Corticotropin-releasing factor receptor 1, OLEIC ACID, ... | | 著者 | Dore, A.S, Bortolato, A, Hollenstein, K, Cheng, R.K.Y, Read, R.J, Marshall, F.H. | | 登録日 | 2015-04-10 | | 公開日 | 2016-06-29 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.183 Å) | | 主引用文献 | Decoding Corticotropin-Releasing Factor Receptor Type 1 Crystal Structures.
Curr Mol Pharmacol, 10, 2017
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3MIW
 | | Crystal Structure of Rotavirus NSP4 | | 分子名称: | 1,2-ETHANEDIOL, Non-structural glycoprotein 4 | | 著者 | Chacko, A.R, Read, R.J, Dodson, E.J, Rao, D.C, Suguna, K. | | 登録日 | 2010-04-12 | | 公開日 | 2011-05-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A new pentameric structure of rotavirus NSP4 revealed by molecular replacement.
Acta Crystallogr.,Sect.D, 68, 2012
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4UFJ
 | | Mouse Galactocerebrosidase complexed with iso-galacto-fagomine lactam IGL | | 分子名称: | (3S,4S,5R)-5-(hydroxymethyl)-3,4-bis(oxidanyl)piperidin-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E. | | 登録日 | 2015-03-17 | | 公開日 | 2015-03-25 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Chem.Sci., 6, 2015
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4UFM
 | | Mouse Galactocerebrosidase complexed with 1-deoxy-galacto-nojirimycin DGJ | | 分子名称: | (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Hill, C.H, Viuff, A.H, Spratley, S.J, Salamone, S, Christensen, S.H, Read, R.J, Moriarty, N.W, Jensen, H.H, Deane, J.E. | | 登録日 | 2015-03-17 | | 公開日 | 2015-04-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Azasugar Inhibitors as Pharmacological Chaperones for Krabbe Disease.
Chem.Sci., 6, 2015
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4UEX
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4V0X
 | | The crystal structure of mouse PP1G in complex with truncated human PPP1R15B (631-684) | | 分子名称: | MANGANESE (II) ION, PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 15B, PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUBUNIT | | 著者 | Chen, R, Yan, Y, Casado, A.C, Ron, D, Read, R.J. | | 登録日 | 2014-09-18 | | 公開日 | 2015-03-25 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | G-actin provides substrate-specificity to eukaryotic initiation factor 2 alpha holophosphatases.
Elife, 4, 2015
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2R82
 | | Pyruvate phosphate dikinase (PPDK) triple mutant R219E/E271R/S262D adapts a second conformational state | | 分子名称: | Pyruvate, phosphate dikinase, SULFATE ION | | 著者 | Lim, K, Read, R.J, Chen, C.C, Herzberg, O. | | 登録日 | 2007-09-10 | | 公開日 | 2008-01-01 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Swiveling domain mechanism in pyruvate phosphate dikinase.
Biochemistry, 46, 2007
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2RIV
 | | Crystal structure of the reactive loop cleaved human Thyroxine Binding Globulin | | 分子名称: | GLYCEROL, SULFATE ION, Thyroxine-binding globulin | | 著者 | Zhou, A, Wei, Z, Stanley, P.L.D, Read, R.J, Stein, P.E, Carrell, R.W. | | 登録日 | 2007-10-12 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins
J.Biol.Chem., 286, 2011
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2RIW
 | | The Reactive loop cleaved human Thyroxine Binding Globulin complexed with thyroxine | | 分子名称: | 3,5,3',5'-TETRAIODO-L-THYRONINE, Thyroxine-binding globulin | | 著者 | Zhou, A, Wei, Z, Stanley, P.L.D, Read, R.J, Stein, P.E, Carrell, R.W. | | 登録日 | 2007-10-12 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins
J.Biol.Chem., 286, 2011
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5M3X
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5M3Y
 | | Crystal structure of human glycosylated angiotensinogen | | 分子名称: | Angiotensinogen, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Yan, Y, Read, R.J. | | 登録日 | 2016-10-17 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis for the specificity of renin-mediated angiotensinogen cleavage.
J. Biol. Chem., 294, 2019
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1QOH
 | | A MUTANT SHIGA-LIKE TOXIN IIE | | 分子名称: | SHIGA-LIKE TOXIN IIE B SUBUNIT | | 著者 | Pannu, N.S, Boodhoo, A, Armstrong, G.D, Clark, C.G, Brunton, J.L, Read, R.J. | | 登録日 | 1999-11-08 | | 公開日 | 2000-07-03 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | A Mutant Shiga-Like Toxin Iie Bound to its Receptor Gb(3): Structure of a Group II Shiga-Like Toxin with Altered Binding Specificity
Structure, 8, 2000
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1QNU
 | | Shiga-Like Toxin I B Subunit Complexed with the Bridged-Starfish Inhibitor | | 分子名称: | ETHYL-CARBAMIC ACID METHYL ESTER, METHYL-CARBAMIC ACID ETHYL ESTER, Shiga toxin 1 variant B subunit, ... | | 著者 | Pannu, N.S, Hayakawa, K, Read, R.J. | | 登録日 | 1999-10-21 | | 公開日 | 2000-04-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands.
Nature, 403, 2000
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1PTO
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2BOS
 | | A MUTANT SHIGA-LIKE TOXIN IIE BOUND TO ITS RECEPTOR | | 分子名称: | N-BUTANE, PROTEIN (SHIGA-LIKE TOXIN IIE B SUBUNIT), alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose, ... | | 著者 | Ling, H, Boodhoo, A, Armstrong, G.D, Clark, C.G, Brunton, J.L, Read, R.J. | | 登録日 | 1998-10-20 | | 公開日 | 1999-10-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A mutant Shiga-like toxin IIe bound to its receptor Gb(3): structure of a group II Shiga-like toxin with altered binding specificity.
Structure Fold.Des., 8, 2000
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