3BHU
 
 | | Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor meriolin 5 | | Descriptor: | 4-(4-propoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-amine, Cell division protein kinase 2, Cyclin-A2, ... | | Authors: | Echalier, A, Bettayeb, K, Ferandin, Y, Lozach, O, Clement, M, Valette, A, Liger, F, Marquet, B, Morris, J.C, Endicott, J.A, Joseph, B, Meijer, L. | | Deposit date: | 2007-11-29 | | Release date: | 2008-02-12 | | Last modified: | 2017-10-25 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Meriolins, a new class of cell death inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases
Cancer Res., 67, 2007
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2Z5E
 | | Crystal Structure of Proteasome Assembling Chaperone 3 | | Descriptor: | Proteasome Assembling Chaperone 3 | | Authors: | Okamoto, K, Kurimoto, E, Sakata, E, Suzuki, A, Yamane, T, Hirano, Y, Murata, S, Tanaka, K, Kato, K. | | Deposit date: | 2007-07-06 | | Release date: | 2008-02-19 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes
Nat.Struct.Mol.Biol., 15, 2008
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2Z5C
 | | Crystal Structure of a Novel Chaperone Complex for Yeast 20S Proteasome Assembly | | Descriptor: | Proteasome component PUP2, Protein YPL144W, Uncharacterized protein YLR021W | | Authors: | Yashiroda, H, Mizushima, T, Okamoto, K, Kameyama, T, Hayashi, H, Kishimoto, T, Kasahara, M, Kurimoto, E, Sakata, E, Suzuki, A, Hirano, Y, Murata, S, Kato, K, Yamane, T, Tanaka, K. | | Deposit date: | 2007-07-03 | | Release date: | 2008-01-22 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes
Nat.Struct.Mol.Biol., 15, 2008
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2ZSI
 | | Structural basis of gibberellin(GA4)-induced DELLA recognition by the gibberellin receptor | | Descriptor: | DELLA protein GAI, GIBBERELLIN A4, Probable gibberellin receptor GID1L1 | | Authors: | Murase, K, Hirano, Y, Sun, T.P, Hakoshima, T. | | Deposit date: | 2008-09-10 | | Release date: | 2008-11-25 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Gibberellin-induced DELLA recognition by the gibberellin receptor GID1
Nature, 456, 2008
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6B19
 | | Architecture of HIV-1 reverse transcriptase initiation complex core | | Descriptor: | RNA genome fragment, reverse transcriptase p51 subunit, reverse transcriptase p66 subunit, ... | | Authors: | Larsen, K.P, Mathiharan, Y.K, Chen, D.H, Puglisi, J.D, Skiniotis, G, Puglisi, E.V. | | Deposit date: | 2017-09-18 | | Release date: | 2018-04-25 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Architecture of an HIV-1 reverse transcriptase initiation complex.
Nature, 557, 2018
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2ZSH
 | | Structural basis of gibberellin(GA3)-induced DELLA recognition by the gibberellin receptor | | Descriptor: | DELLA protein GAI, GIBBERELLIN A3, Probable gibberellin receptor GID1L1 | | Authors: | Murase, K, Hirano, Y, Sun, T.P, Hakoshima, T. | | Deposit date: | 2008-09-10 | | Release date: | 2008-11-25 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Gibberellin-induced DELLA recognition by the gibberellin receptor GID1
Nature, 456, 2008
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2Z5B
 | | Crystal Structure of a Novel Chaperone Complex for Yeast 20S Proteasome Assembly | | Descriptor: | Protein YPL144W, Uncharacterized protein YLR021W | | Authors: | Yashiroda, H, Mizushima, T, Okamoto, K, Kameyama, T, Hayashi, H, Kishimoto, T, Kasahara, M, Kurimoto, E, Sakata, E, Suzuki, A, Hirano, Y, Murata, S, Kato, K, Yamane, T, Tanaka, K. | | Deposit date: | 2007-07-03 | | Release date: | 2008-01-22 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes
Nat.Struct.Mol.Biol., 15, 2008
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3A38
 | | Crystal structure of high-potential iron-sulfur protein from Thermochromatium tepidum at 0.7 angstrom resolution | | Descriptor: | GLYCEROL, High-potential iron-sulfur protein, IRON/SULFUR CLUSTER, ... | | Authors: | Takeda, K, Kusumoto, K, Hirano, Y, Miki, K. | | Deposit date: | 2009-06-10 | | Release date: | 2010-01-26 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (0.7 Å) | | Cite: | Detailed assessment of X-ray induced structural perturbation in a crystalline state protein.
J.Struct.Biol., 169, 2010
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6CQF
 | | Crystal structure of HPK1 in complex an inhibitor G1858 | | Descriptor: | Mitogen-activated protein kinase kinase kinase kinase 1, N-{2-(3,3-difluoropyrrolidin-1-yl)-6-[(3R)-pyrrolidin-3-yl]pyrimidin-4-yl}-1-(propan-2-yl)-1H-pyrazolo[4,3-c]pyridin-6-amine | | Authors: | Wu, P, Lehoux, I, Mortara, K, Franke, Y, Chan, B.K, Wang, W. | | Deposit date: | 2018-03-15 | | Release date: | 2018-12-19 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.246 Å) | | Cite: | Hematopoietic Progenitor Kinase-1 Structure in a Domain-Swapped Dimer.
Structure, 27, 2019
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8T6V
 | | Cryo-EM structure of human Anion Exchanger 1 bound to 4,4'-Diisothiocyanatostilbene-2,2'-Disulfonic Acid (DIDS) | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid, ... | | Authors: | Capper, M.J, Zilberg, G, Mathiharan, Y.K, Yang, S, Stone, A.C, Wacker, D. | | Deposit date: | 2023-06-18 | | Release date: | 2023-09-13 | | Last modified: | 2023-11-01 | | Method: | ELECTRON MICROSCOPY (2.95 Å) | | Cite: | Substrate binding and inhibition of the anion exchanger 1 transporter.
Nat.Struct.Mol.Biol., 30, 2023
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8T6U
 | | Cryo-EM structure of human Anion Exchanger 1 bound to Dipyridamole | | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Capper, M.J, Zilberg, G, Mathiharan, Y.K, Yang, S, Stone, A.C, Wacker, D. | | Deposit date: | 2023-06-18 | | Release date: | 2023-09-13 | | Last modified: | 2023-11-01 | | Method: | ELECTRON MICROSCOPY (3.13 Å) | | Cite: | Substrate binding and inhibition of the anion exchanger 1 transporter.
Nat.Struct.Mol.Biol., 30, 2023
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6L8A
 | | Tetrathionate hydrolase from Acidithiobacillus ferrooxidans | | Descriptor: | BETA-ALANINE, GLYCINE, SULFATE ION, ... | | Authors: | Tamada, T, Hirano, Y. | | Deposit date: | 2019-11-05 | | Release date: | 2020-11-11 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.95004809 Å) | | Cite: | Reaction mechanism of tetrathionate hydrolysis based on the crystal structure of tetrathionate hydrolase from Acidithiobacillus ferrooxidans.
Protein Sci., 30, 2020
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1YHJ
 | | Crystal Structure of Pyridoxal Kinase in Complex with Roscovitine and Derivatives | | Descriptor: | (2R)-2-{[6-(BENZYLOXY)-9-ISOPROPYL-9H-PURIN-2-YL]AMINO}BUTAN-1-OL, Pyridoxal Kinase | | Authors: | Tang, L, Li, M.-H, Cao, P, Wang, F, Chang, W.-R, Bach, S, Reinhardt, J, Ferandin, Y, Koken, M, Galons, H, Wan, Y, Gray, N, Meijer, L, Jiang, T, Liang, D.-C. | | Deposit date: | 2005-01-09 | | Release date: | 2005-07-05 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of pyridoxal kinase in complex with roscovitine and derivatives.
J.Biol.Chem., 280, 2005
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1YGJ
 | | Crystal Structure of Pyridoxal Kinase in Complex with Roscovitine and Derivatives | | Descriptor: | (2R)-2-({6-[BENZYL(METHYL)AMINO]-9-ISOPROPYL-9H-PURIN-2-YL}AMINO)BUTAN-1-OL, Pyridoxal kinase | | Authors: | Tang, L, Li, M.-H, Cao, P, Wang, F, Chang, W.-R, Bach, S, Reinhardt, J, Ferandin, Y, Koken, M, Galons, H, Wan, Y, Gray, N, Meijer, L, Jiang, T, Liang, D.-C. | | Deposit date: | 2005-01-05 | | Release date: | 2005-07-05 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of pyridoxal kinase in complex with roscovitine and derivatives
J.Biol.Chem., 280, 2005
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6M3D
 | | X-ray crystal structure of tandemly connected engrailed homeodomains (EHD) with R53A mutations and DNA complex | | Descriptor: | DNA (5'-D(*GP*GP*AP*TP*TP*AP*GP*GP*AP*TP*TP*A)-3'), DNA (5'-D(*TP*AP*AP*TP*CP*CP*TP*AP*AP*TP*CP*C)-3'), SODIUM ION, ... | | Authors: | Sunami, T, Hirano, Y, Tamada, T, Kono, H. | | Deposit date: | 2020-03-03 | | Release date: | 2020-09-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural basis for designing an array of engrailed homeodomains.
Acta Crystallogr D Struct Biol, 76, 2020
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5B5F
 | | Crystal structure of ALiS3-Streptavidin complex | | Descriptor: | N-methyl-3-(4-oxo-4,5-dihydrofuro[3,2-c]pyridin-2-yl)benzenesulfonamide, Streptavidin | | Authors: | Sugiyama, S, Terai, T, Kakinouchi, K, Fujikake, R, Nagano, T, Urano, Y. | | Deposit date: | 2016-05-04 | | Release date: | 2017-03-01 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Improving the Solubility of Artificial Ligands of Streptavidin to Enable More Practical Reversible Switching of Protein Localization in Cells
Chembiochem, 18, 2017
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5B5G
 | | Crystal structure of ALiS4-Streptavidin complex | | Descriptor: | SULFITE ION, Streptavidin, methyl 5-(4-oxidanylidene-5~{H}-furo[3,2-c]pyridin-2-yl)pyridine-3-carboxylate | | Authors: | Sugiyama, S, Terai, T, Kakinouchi, K, Fujikake, R, Nagano, T, Urano, Y. | | Deposit date: | 2016-05-04 | | Release date: | 2017-03-01 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Improving the Solubility of Artificial Ligands of Streptavidin to Enable More Practical Reversible Switching of Protein Localization in Cells
Chembiochem, 18, 2017
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1YGK
 | | Crystal Structure of Pyridoxal Kinase in Complex with Roscovitine and Derivatives | | Descriptor: | Pyridoxal kinase, R-ROSCOVITINE | | Authors: | Tang, L, Li, M.-H, Cao, P, Wang, F, Chang, W.-R, Bach, S, Reinhardt, J, Ferandin, Y, Koken, M, Galons, H, Wan, Y, Gray, N, Meijer, L, Jiang, T, Liang, D.-C. | | Deposit date: | 2005-01-05 | | Release date: | 2005-07-05 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of pyridoxal kinase in complex with roscovitine and derivatives
J.Biol.Chem., 280, 2005
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2BJO
 | | Crystal Structure of the Organic Hydroperoxide Resistance Protein OhrB of Bacillus subtilis | | Descriptor: | ORGANIC HYDROPEROXIDE RESISTANCE PROTEIN OHRB | | Authors: | Cooper, D.R, Surendranath, Y, Bielnicki, J, Devedjiev, Y, Joachimiak, A, Derewenda, Z.S. | | Deposit date: | 2005-02-04 | | Release date: | 2006-03-09 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure of the Bacillus Subtilis Ohrb Hydroperoxide-Resistance Protein in a Fully Oxidized State.
Acta Crystallogr.,Sect.D, 63, 2007
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3W05
 | | Crystal structure of Oryza sativa DWARF14 (D14) in complex with PMSF | | Descriptor: | 1,2-ETHANEDIOL, Dwarf 88 esterase, phenylmethanesulfonic acid | | Authors: | Kagiyama, M, Hirano, Y, Mori, T, Kim, S.Y, Kyozuka, J, Seto, Y, Yamaguchi, S, Hakoshima, T. | | Deposit date: | 2012-10-19 | | Release date: | 2013-01-23 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Structures of D14 and D14L in the strigolactone and karrikin signaling pathways
Genes Cells, 18, 2013
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1SBR
 | | The structure and function of B. subtilis YkoF gene product: the complex with thiamin | | Descriptor: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, CALCIUM ION, ykoF | | Authors: | Devedjiev, Y, Surendranath, Y, Derewenda, U, Derewenda, Z.S. | | Deposit date: | 2004-02-11 | | Release date: | 2004-10-05 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The Structure and Ligand Binding Properties of the B.subtilis YkoF Gene Product, a Member of a Novel Family of Thiamin/HMP-binding Proteins
J.Mol.Biol., 343, 2004
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1S99
 | | The structure and function of B. subtilis YkoF gene product: ligand free protein | | Descriptor: | ACETATE ION, CALCIUM ION, ykoF | | Authors: | Devedjiev, Y, Surendranath, Y, Derewenda, U, Derewenda, Z.S. | | Deposit date: | 2004-02-04 | | Release date: | 2004-10-05 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | The Structure and Ligand Binding Properties of the B.subtilis YkoF Gene Product, a Member of a Novel Family of Thiamin/HMP-binding Proteins
J.Mol.Biol., 343, 2004
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3W06
 | | Crystal structure of Arabidopsis thaliana DWARF14 Like (AtD14L) | | Descriptor: | 1,2-ETHANEDIOL, Hydrolase, alpha/beta fold family protein | | Authors: | Kagiyama, M, Hirano, Y, Mori, T, Kim, S.Y, Kyozuka, J, Seto, Y, Yamaguchi, S, Hakoshima, T. | | Deposit date: | 2012-10-19 | | Release date: | 2013-01-23 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.15 Å) | | Cite: | Structures of D14 and D14L in the strigolactone and karrikin signaling pathways
Genes Cells, 18, 2013
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3W04
 | | Crystal structure of Oryza sativa DWARF14 (D14) | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | Authors: | Kagiyama, M, Hirano, Y, Mori, T, Kim, S.Y, Kyozuka, J, Seto, Y, Yamaguchi, S, Hakoshima, T. | | Deposit date: | 2012-10-19 | | Release date: | 2013-01-23 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structures of D14 and D14L in the strigolactone and karrikin signaling pathways
Genes Cells, 18, 2013
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4P9T
 | | Structure of the free form of the N-terminal VH1 domain of monomeric alpha-catenin | | Descriptor: | 1,2-ETHANEDIOL, Catenin alpha-2, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Shibahara, T, Hirano, Y, Hakoshima, T. | | Deposit date: | 2014-04-04 | | Release date: | 2015-04-29 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of the free form of the N-terminal VH1 domain of monomeric alpha-catenin.
Febs Lett., 589, 2015
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