1NQI
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![BU of 1nqi by Molmil](/molmil-images/mine/1nqi) | crystal structure of lactose synthase, a 1:1 complex between beta1,4-galactosyltransferase and alpha-lactalbumin in the presence of GlcNAc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-LACTALBUMIN, BETA-1,4-GALACTOSYLTRANSFERASE, ... | Authors: | Ramakrishnan, B, Qasba, P.K. | Deposit date: | 2003-01-21 | Release date: | 2003-02-04 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of lactose synthase reveals a large conformational
change in its catalytic component, the beta-1,4-galactosyltransferase J.Mol.Biol., 310, 2001
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1NHE
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![BU of 1nhe by Molmil](/molmil-images/mine/1nhe) | Crystal structure of Lactose synthase complex with UDP | Descriptor: | ALPHA-LACTALBUMIN, BETA-1,4-GALACTOSYLTRANSFERASE, CALCIUM ION, ... | Authors: | Ramakrishnan, B, Qasba, P.K. | Deposit date: | 2002-12-19 | Release date: | 2003-01-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of lactose synthase reveals a large conformational change in its catalytic component, the beta-1,4-galactosyltransferase J.Mol.Biol., 310, 2001
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1NF5
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![BU of 1nf5 by Molmil](/molmil-images/mine/1nf5) | Crystal Structure of Lactose Synthase, Complex with Glucose | Descriptor: | 1,2-ETHANEDIOL, Alpha-lactalbumin, CALCIUM ION, ... | Authors: | Ramakrishnan, B, Qasba, P.K. | Deposit date: | 2002-12-13 | Release date: | 2002-12-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Lactose Synthase Reveals a Large Conformational Change in its Catalytic Component, the beta-1,4-galactosyltransferase J.Mol.Biol., 310, 2001
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1NWG
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![BU of 1nwg by Molmil](/molmil-images/mine/1nwg) | BETA-1,4-GALACTOSYLTRANSFERASE COMPLEX WITH ALPHA-LACTALBUMIN AND N-BUTANOYL-GLUCOAMINE | Descriptor: | 2-(butanoylamino)-2-deoxy-beta-D-glucopyranose, Alpha-lactalbumin, CALCIUM ION, ... | Authors: | Ramakrishnan, B, Shah, P.S, Qasba, P.K. | Deposit date: | 2003-02-06 | Release date: | 2003-02-18 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | ALPHA-LACTALBUMIN (LA) STIMULATES MILK
BETA-1,4-GALACTOSYLTRANSFERASE I (BETA 4GAL-T1) TO
TRANSFER GLUCOSE FROM UDP-GLUCOSE TO
N-ACETYLGLUCOSAMINE. CRYSTAL STRUCTURE OF BETA
4GAL-T1 X LA COMPLEX WITH UDP-GLC. J.Biol.Chem., 276, 2001
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1O0R
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![BU of 1o0r by Molmil](/molmil-images/mine/1o0r) | Crystal structure of the catalytic domain of bovine beta1,4-galactosyltransferase complex with UDP-galactose | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GALACTOSE-URIDINE-5'-DIPHOSPHATE, ... | Authors: | Ramakrishnan, B, Balaji, P.V, Qasba, P.K. | Deposit date: | 2003-02-24 | Release date: | 2003-03-04 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | CRYSTAL STRUCTURE OF BETA 1,4-GALACTOSYLTRANSFERASE COMPLEX WITH UDP-GAL
REVEALS AN OLIGOSACCHARIDE ACCEPTOR BINDING SITE J.Mol.Biol., 318, 2002
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1O23
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![BU of 1o23 by Molmil](/molmil-images/mine/1o23) | CRYSTAL STRUCTURE OF LACTOSE SYNTHASE IN THE PRESENCE OF UDP-GLUCOSE | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ALPHA-LACTALBUMIN, BETA-1,4-GALACTOSYLTRANSFERASE, ... | Authors: | Ramakrishnan, B, Shah, P.S, Qasba, P.K. | Deposit date: | 2003-01-29 | Release date: | 2003-02-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Alpha-Lactalbumin (La) Stimulates Milk Beta-1,4-Galactosyltransferase I (Beta 4Gal-T1) to Transfer Glucose from Udp-Glucose to N-Acetylglucosamine. Crystal Structure of Beta 4Gal-T1 X La Complex with Udp-Glc. J.Biol.Chem., 276, 2001
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1NMM
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![BU of 1nmm by Molmil](/molmil-images/mine/1nmm) | beta-1,4-galactosyltransferase mutant Cys342Thr complex with alpha-lactalbumin and GlcNAc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-LACTALBUMIN, BETA-1,4-GALACTOSYLTRANSFERASE, ... | Authors: | Ramakrishnan, B, Shah, P.S, Qasba, P.K. | Deposit date: | 2003-01-10 | Release date: | 2003-01-21 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | alpha-Lactalbumin (LA) stimulates milk beta-1,4-galactosyltransferase I (beta 4Gal-T1) to transfer glucose from UDP-glucose to N-acetylglucosamine. Crystal structure of beta 4Gal-T1 x LA complex with UDP-Glc. J.Biol.Chem., 276, 2001
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1OQM
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![BU of 1oqm by Molmil](/molmil-images/mine/1oqm) | A 1:1 complex between alpha-lactalbumin and beta1,4-galactosyltransferase in the presence of UDP-N-acetyl-galactosamine | Descriptor: | Alpha-lactalbumin, CALCIUM ION, MANGANESE (II) ION, ... | Authors: | Ramakrishnan, B, Qasba, P.K. | Deposit date: | 2003-03-10 | Release date: | 2003-03-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-based design of beta 1,4-galactosyltransferase I (beta 4Gal-T1) with equally efficient
N-acetylgalactosaminyltransferase activity: point mutation broadens beta 4Gal-T1 donor specificity. J.Biol.Chem., 277, 2002
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1TW1
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![BU of 1tw1 by Molmil](/molmil-images/mine/1tw1) | beta-1,4-galactosyltransferase mutant Met344His (m344H-Gal-T1) complex with UDP-galactose and magnesium | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-1,4-galactosyltransferase 1, ... | Authors: | Ramakrishnan, B, Boeggeman, E, Qasba, P.K. | Deposit date: | 2004-06-30 | Release date: | 2004-12-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Effect of the Met344His mutation on the conformational dynamics of bovine beta-1,4-galactosyltransferase: crystal structure of the Met344His mutant in complex with chitobiose Biochemistry, 43, 2004
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1TVY
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![BU of 1tvy by Molmil](/molmil-images/mine/1tvy) | beta-1,4-galactosyltransferase mutant Met344His (M344H-Gal-T1) complex with UDP-galactose and manganese | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-1,4-galactosyltransferase 1, GALACTOSE-URIDINE-5'-DIPHOSPHATE, ... | Authors: | Ramakrishnan, B, Boeggeman, E, Qasba, P.K. | Deposit date: | 2004-06-30 | Release date: | 2004-12-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Effect of the Met344His mutation on the conformational dynamics of bovine beta-1,4-galactosyltransferase: crystal structure of the Met344His mutant in complex with chitobiose Biochemistry, 43, 2004
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1TW5
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![BU of 1tw5 by Molmil](/molmil-images/mine/1tw5) | beta1,4-galactosyltransferase mutant M344H-Gal-T1 in complex with Chitobiose | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ramakrishnan, B, Boeggeman, E, Qasba, P.K. | Deposit date: | 2004-06-30 | Release date: | 2004-12-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Effect of the Met344His mutation on the conformational dynamics of bovine beta-1,4-galactosyltransferase: crystal structure of the Met344His mutant in complex with chitobiose Biochemistry, 43, 2004
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305D
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![BU of 305d by Molmil](/molmil-images/mine/305d) | |
306D
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![BU of 306d by Molmil](/molmil-images/mine/306d) | |
304D
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![BU of 304d by Molmil](/molmil-images/mine/304d) | |
100D
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![BU of 100d by Molmil](/molmil-images/mine/100d) | |
159D
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![BU of 159d by Molmil](/molmil-images/mine/159d) | SIDE BY SIDE BINDING OF TWO DISTAMYCIN A DRUGS IN THE MINOR GROOVE OF AN ALTERNATING B-DNA DUPLEX | Descriptor: | DISTAMYCIN A, DNA (5'-D(*IP*CP*IP*CP*IP*CP*IP*C)-3'), MAGNESIUM ION | Authors: | Chen, X, Ramakrishnan, B, Rao, S.T, Sundaralingam, M. | Deposit date: | 1994-02-10 | Release date: | 1995-02-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Binding of two distamycin A molecules in the minor groove of an alternating B-DNA duplex. Nat.Struct.Biol., 1, 1994
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161D
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![BU of 161d by Molmil](/molmil-images/mine/161d) | |
393D
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![BU of 393d by Molmil](/molmil-images/mine/393d) | |
327D
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![BU of 327d by Molmil](/molmil-images/mine/327d) | |
1CEH
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![BU of 1ceh by Molmil](/molmil-images/mine/1ceh) | STRUCTURE AND FUNCTION OF THE CATALYTIC SITE MUTANT ASP99ASN OF PHOSPHOLIPASE A2: ABSENCE OF CONSERVED STRUCTURAL WATER | Descriptor: | CALCIUM ION, PHOSPHOLIPASE A2 | Authors: | Kumar, A, Sekharudu, C, Ramakrishnan, B, Dupureur, C.M, Zhu, H, Tsai, M.-D, Sundaralingam, M. | Deposit date: | 1994-11-16 | Release date: | 1995-02-07 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure and function of the catalytic site mutant Asp 99 Asn of phospholipase A2: absence of the conserved structural water. Protein Sci., 3, 1994
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1RCF
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![BU of 1rcf by Molmil](/molmil-images/mine/1rcf) | STRUCTURE OF THE TRIGONAL FORM OF RECOMBINANT OXIDIZED FLAVODOXIN FROM ANABAENA 7120 AT 1.40 ANGSTROMS RESOLUTION | Descriptor: | FLAVIN MONONUCLEOTIDE, FLAVODOXIN, SULFATE ION | Authors: | Burkhart, B, Ramakrishnan, B, Yan, H, Reedstrom, R, Markley, J, Straus, N, Sundaralingam, M. | Deposit date: | 1994-10-31 | Release date: | 1995-01-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structure of the trigonal form of recombinant oxidized flavodoxin from Anabaena 7120 at 1.40 A resolution. Acta Crystallogr.,Sect.D, 51, 1995
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4IRP
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![BU of 4irp by Molmil](/molmil-images/mine/4irp) | Crystal structure of catalytic domain of human beta1,4-galactosyltransferase-7 in open conformation with manganses and UDP | Descriptor: | ACETATE ION, Beta-1,4-galactosyltransferase 7, IMIDAZOLE, ... | Authors: | Tsutsui, Y, Ramakrishnan, B, Qasba, P.K. | Deposit date: | 2013-01-15 | Release date: | 2013-09-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of beta-1,4-Galactosyltransferase 7 Enzyme Reveal Conformational Changes and Substrate Binding. J.Biol.Chem., 288, 2013
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2AES
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![BU of 2aes by Molmil](/molmil-images/mine/2aes) | Crystal Structure of Human M340H-Beta1,4-Galactosyltransferase-I (M340H-B4Gal-T1) in Complex with GlcNAc-beta1,2-Man-alpha1,3-Man-beta-OR | Descriptor: | 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose, ... | Authors: | Ramasamy, V, Ramakrishnan, B, Boeggeman, E, Ratner, D.M, Seeberger, P.H, Qasba, P.K. | Deposit date: | 2005-07-23 | Release date: | 2005-10-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Oligosaccharide Preferences of beta1,4-Galactosyltransferase-I: Crystal Structures of Met340His Mutant of Human beta1,4-Galactosyltransferase-I with a Pentasaccharide and Trisaccharides of the N-Glycan Moiety J.Mol.Biol., 353, 2005
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246D
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![BU of 246d by Molmil](/molmil-images/mine/246d) | STRUCTURE OF THE PURINE-PYRIMIDINE ALTERNATING RNA DOUBLE HELIX, R(GUAUAUA)D(C) , WITH A 3'-TERMINAL DEOXY RESIDUE | Descriptor: | DNA/RNA (5'-R(*GP*UP*AP*UP*AP*UP*AP*)-D(*C)-3'), SODIUM ION | Authors: | Wahl, M.C, Ban, C, Sekharudu, C, Ramakrishnan, B, Sundaralingam, M. | Deposit date: | 1996-01-25 | Release date: | 1996-08-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the purine-pyrimidine alternating RNA double helix, r(GUAUAUA)d(C), with a 3'-terminal deoxy residue. Acta Crystallogr.,Sect.D, 52, 1996
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4IRQ
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![BU of 4irq by Molmil](/molmil-images/mine/4irq) | Crystal structure of catalytic domain of human beta1,4galactosyltransferase 7 in closed conformation in complex with manganese and UDP | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-1,4-galactosyltransferase 7, MANGANESE (II) ION, ... | Authors: | Tsutsui, Y, Ramakrishnan, B, Qasba, P.K. | Deposit date: | 2013-01-15 | Release date: | 2013-09-25 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of beta-1,4-galactosyltransferase 7 enzyme reveal conformational changes and substrate binding. J.Biol.Chem., 288, 2013
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