4IRP
Crystal structure of catalytic domain of human beta1,4-galactosyltransferase-7 in open conformation with manganses and UDP
Summary for 4IRP
Entry DOI | 10.2210/pdb4irp/pdb |
Related | 4IRQ |
Descriptor | Beta-1,4-galactosyltransferase 7, URIDINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... (6 entities in total) |
Functional Keywords | gt-a fold, open conformation, manganese and udp complex, glycosyltransferase, golgi, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: Q9UBV7 |
Total number of polymer chains | 2 |
Total formula weight | 59774.09 |
Authors | Tsutsui, Y.,Ramakrishnan, B.,Qasba, P.K. (deposition date: 2013-01-15, release date: 2013-09-25, Last modification date: 2023-09-20) |
Primary citation | Tsutsui, Y.,Ramakrishnan, B.,Qasba, P.K. Crystal Structures of beta-1,4-Galactosyltransferase 7 Enzyme Reveal Conformational Changes and Substrate Binding. J.Biol.Chem., 288:31963-31970, 2013 Cited by PubMed: 24052259DOI: 10.1074/jbc.M113.509984 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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