4IRP
Crystal structure of catalytic domain of human beta1,4-galactosyltransferase-7 in open conformation with manganses and UDP
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE UDP A 401 |
| Chain | Residue |
| A | PRO100 |
| A | MN402 |
| A | HOH579 |
| A | HOH617 |
| A | PHE101 |
| A | ARG102 |
| A | ARG104 |
| A | PHE139 |
| A | ASP163 |
| A | VAL164 |
| A | ASP165 |
| A | TYR194 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN A 402 |
| Chain | Residue |
| A | ASP165 |
| A | HIS257 |
| A | UDP401 |
| A | HOH653 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 403 |
| Chain | Residue |
| A | ARG138 |
| A | PHE139 |
| A | GLY223 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 404 |
| Chain | Residue |
| A | ASP79 |
| A | PRO81 |
| A | ARG117 |
| A | ARG297 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT A 405 |
| Chain | Residue |
| A | GLY91 |
| A | PRO92 |
| A | HOH650 |
| B | ALA88 |
| B | GLY91 |
| B | PRO92 |
| B | HOH637 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 406 |
| Chain | Residue |
| A | ASP174 |
| A | GLY176 |
| A | PHE177 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IMD A 407 |
| Chain | Residue |
| A | PHE243 |
| A | HOH605 |
| A | HOH608 |
| B | HOH578 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE UDP B 401 |
| Chain | Residue |
| B | PRO100 |
| B | PHE101 |
| B | ARG102 |
| B | ARG104 |
| B | PHE139 |
| B | ASP163 |
| B | VAL164 |
| B | ASP165 |
| B | TYR194 |
| B | MN402 |
| B | HOH501 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN B 402 |
| Chain | Residue |
| B | ASP165 |
| B | HIS257 |
| B | UDP401 |
| B | HOH636 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT B 403 |
| Chain | Residue |
| B | PRO92 |
| B | SER155 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT B 404 |
| Chain | Residue |
| B | TRP84 |
| B | GLU85 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24052259","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4IRP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4IRQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24052259","evidenceCode":"ECO:0000303"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24052259","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4IRQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
