1NWG

BETA-1,4-GALACTOSYLTRANSFERASE COMPLEX WITH ALPHA-LACTALBUMIN AND N-BUTANOYL-GLUCOAMINE

Replaces:  1JNA

Summary for 1NWG

DescriptorAlpha-lactalbumin, beta-1,4-galactosyltransferase, CALCIUM ION, ... (5 entities in total)
Functional Keywordsalpha-lactalbumin; beta1, 4-galactosyltransferase; n-butanoyl-glucoamine, transferase activator-transferase complex, transferase activator/transferase
Biological sourceMus musculus (house mouse)
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Cellular locationSecreted P29752
Isoform Long: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Isoform Short: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Processed beta-1,4-galactosyltransferase 1: Secreted P08037
Total number of polymer chains4
Total molecular weight94313.58
Authors
Ramakrishnan, B.,Shah, P.S.,Qasba, P.K. (deposition date: 2003-02-06, release date: 2003-02-18, Last modification date: 2011-07-13)
Primary citation
Ramakrishnan, B.,Shah, P.S.,Qasba, P.K.
ALPHA-LACTALBUMIN (LA) STIMULATES MILK BETA-1,4-GALACTOSYLTRANSFERASE I (BETA 4GAL-T1) TO TRANSFER GLUCOSE FROM UDP-GLUCOSE TO N-ACETYLGLUCOSAMINE. CRYSTAL STRUCTURE OF BETA 4GAL-T1 X LA COMPLEX WITH UDP-GLC.
J.Biol.Chem., 276:37665-37671, 2001
PubMed: 11485999 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M102458200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.32 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.273231.3%5.8%4.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1nwg
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Molmil generated image of 1nwg
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Molmil generated image of 1nwg
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More Biological unit images

Molmil generated image of 1nwg
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Molmil generated image of 1nwg
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Molmil generated image of 1nwg
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (1nwg.pdb1.gz [76.67 KB])
Coordinate files for Biological unit (1nwg.pdb2.gz [74.77 KB])