1NWG
BETA-1,4-GALACTOSYLTRANSFERASE COMPLEX WITH ALPHA-LACTALBUMIN AND N-BUTANOYL-GLUCOAMINE
Replaces: 1JNAFunctional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003796 | molecular_function | lysozyme activity |
| A | 0004461 | molecular_function | lactose synthase activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005989 | biological_process | lactose biosynthetic process |
| A | 0032991 | cellular_component | protein-containing complex |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050829 | biological_process | defense response to Gram-negative bacterium |
| A | 0050830 | biological_process | defense response to Gram-positive bacterium |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| C | 0003796 | molecular_function | lysozyme activity |
| C | 0004461 | molecular_function | lactose synthase activity |
| C | 0005509 | molecular_function | calcium ion binding |
| C | 0005515 | molecular_function | protein binding |
| C | 0005576 | cellular_component | extracellular region |
| C | 0005989 | biological_process | lactose biosynthetic process |
| C | 0032991 | cellular_component | protein-containing complex |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0050829 | biological_process | defense response to Gram-negative bacterium |
| C | 0050830 | biological_process | defense response to Gram-positive bacterium |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0016757 | molecular_function | glycosyltransferase activity |
Functional Information from PROSITE/UniProt
| site_id | PS00128 |
| Number of Residues | 19 |
| Details | GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CgisCdkLlddELdddiaC |
| Chain | Residue | Details |
| A | CYS73-CYS91 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | BINDING: |
| Chain | Residue | Details |
| B | ASP254 | |
| B | LEU255 | |
| B | GLY315 | |
| B | GLU317 | |
| B | SER348 | |
| B | PHE360 | |
| D | PHE188 | |
| D | ASN227 | |
| D | ASP254 | |
| D | LEU255 | |
| D | GLY315 | |
| D | GLU317 | |
| D | SER348 | |
| D | PHE360 | |
| B | PHE188 | |
| B | ASN227 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN45 | |
| C | ASN45 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 8 |
| Details | M-CSA 570 |
| Chain | Residue | Details |
| B | GLY315 | electrostatic stabiliser, hydrogen bond donor |
| B | ASP318 | electrostatic stabiliser, hydrogen bond acceptor |
| B | ASP319 | activator, electrostatic stabiliser, proton acceptor, proton donor |
| B | ILE345 | metal ligand |
| B | SER348 | metal ligand |
| B | ASP350 | electrostatic stabiliser, hydrogen bond donor |
| B | VAL253 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
| B | LEU255 | metal ligand |
| site_id | MCSA2 |
| Number of Residues | 8 |
| Details | M-CSA 570 |
| Chain | Residue | Details |
| D | VAL253 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor |
| D | LEU255 | metal ligand |
| D | GLY315 | electrostatic stabiliser, hydrogen bond donor |
| D | ASP318 | electrostatic stabiliser, hydrogen bond acceptor |
| D | ASP319 | activator, electrostatic stabiliser, proton acceptor, proton donor |
| D | ILE345 | metal ligand |
| D | SER348 | metal ligand |
| D | ASP350 | electrostatic stabiliser, hydrogen bond donor |
