5JP7
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4PJ7
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![BU of 4pj7 by Molmil](/molmil-images/mine/4pj7) | Structure of human MR1-5-OP-RU in complex with human MAIT TRBV6-4 TCR | Descriptor: | 1-deoxy-1-({2,6-dioxo-5-[(E)-propylideneamino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ... | Authors: | Birkinshaw, R.W, Rossjohn, J. | Deposit date: | 2014-05-12 | Release date: | 2014-07-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells. J.Exp.Med., 211, 2014
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5OG5
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![BU of 5og5 by Molmil](/molmil-images/mine/5og5) | Cu nitrite reductase serial data at varying temperatures RT 0.21MGy | Descriptor: | ACETATE ION, COPPER (II) ION, Copper-containing nitrite reductase, ... | Authors: | Horrell, S, Kekilli, D, Strange, R.W, Hough, M.A. | Deposit date: | 2017-07-11 | Release date: | 2018-05-23 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Enzyme catalysis captured using multiple structures from one crystal at varying temperatures. IUCrJ, 5, 2018
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3T09
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![BU of 3t09 by Molmil](/molmil-images/mine/3t09) | E. coli (LacZ) beta-galactosidase (S796A) galactonolactone complex | Descriptor: | Beta-galactosidase, D-galactonolactone, DIMETHYL SULFOXIDE, ... | Authors: | Jancewicz, L.J, Wheatley, R.W, Sutendra, G, Lee, M, Fraser, M, Huber, R.E. | Deposit date: | 2011-07-19 | Release date: | 2012-01-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Ser-796 of Beta-Galactosidase (E. coli) Plays a Key Role in Maintaining an Optimum Balance between the Opened and Closed Conformations of the Catalytically Important Active Site Loop Arch.Biochem.Biophys., 517, 2012
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2ETE
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![BU of 2ete by Molmil](/molmil-images/mine/2ete) | Recombinant oxalate oxidase in complex with glycolate | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYOXYLIC ACID, MANGANESE (II) ION, ... | Authors: | Opaleye, O, Rose, R.-S, Whittaker, M.M, Woo, E.-J, Whittaker, J.W, Pickersgill, R.W. | Deposit date: | 2005-10-27 | Release date: | 2005-11-22 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural and spectroscopic studies shed light on the mechanism of oxalate oxidase J.Biol.Chem., 281, 2006
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3D1Z
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![BU of 3d1z by Molmil](/molmil-images/mine/3d1z) | Crystal structure of HIV-1 mutant I54M and inhibitor DARUNAVIR | Descriptor: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETIC ACID, CHLORIDE ION, ... | Authors: | Liu, F, Kovalesky, A.Y, Tie, Y, Ghosh, A.K, Harrison, R.W, Weber, I.T. | Deposit date: | 2008-05-07 | Release date: | 2008-05-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Effect of flap mutations on structure of HIV-1 protease and inhibition by saquinavir and darunavir. J.Mol.Biol., 381, 2008
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5JW4
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![BU of 5jw4 by Molmil](/molmil-images/mine/5jw4) | Structure of MEDI8852 Fab Fragment in Complex with H5 HA | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | Authors: | Neu, U, Collins, P.J, Walker, P.A, Vorlaender, M.K, Ogrodowicz, R.W, Martin, S.R, Gamblin, S.J, Skehel, J.J. | Deposit date: | 2016-05-11 | Release date: | 2016-08-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes. Cell, 166, 2016
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5C4R
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![BU of 5c4r by Molmil](/molmil-images/mine/5c4r) | CobK precorrin-6A reductase | Descriptor: | Precorrin-6A reductase | Authors: | Gu, S, Pickersgill, R.W. | Deposit date: | 2015-06-18 | Release date: | 2016-11-16 | Last modified: | 2017-08-30 | Method: | X-RAY DIFFRACTION (3.17 Å) | Cite: | Crystal structure of CobK reveals strand-swapping between Rossmann-fold domains and molecular basis of the reduced precorrin product trap. Sci Rep, 5, 2015
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5JT4
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![BU of 5jt4 by Molmil](/molmil-images/mine/5jt4) | L16A mutant of cytochrome c prime from Alcaligenes xylosoxidans: Ferrous state | Descriptor: | ASCORBIC ACID, Cytochrome c', HEME C, ... | Authors: | Kekilli, D, Strange, R.W, Hough, M.A. | Deposit date: | 2016-05-09 | Release date: | 2017-03-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Engineering proximal vs. distal heme-NO coordination via dinitrosyl dynamics: implications for NO sensor design. Chem Sci, 8, 2017
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3UTK
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4N8M
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![BU of 4n8m by Molmil](/molmil-images/mine/4n8m) | Structural polymorphism in the N-terminal oligomerization domain of NPM1 | Descriptor: | COBALT (II) ION, Nucleophosmin | Authors: | Mitrea, D, Royappa, G, Buljan, M, Yun, M, Pytel, N, Satumba, J, Nourse, A, Park, C, Babu, M.M, White, S.W, Kriwacki, R.W. | Deposit date: | 2013-10-17 | Release date: | 2014-03-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.802 Å) | Cite: | Structural polymorphism in the N-terminal oligomerization domain of NPM1. Proc.Natl.Acad.Sci.USA, 111, 2014
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3VD4
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![BU of 3vd4 by Molmil](/molmil-images/mine/3vd4) | E. coli (lacZ) beta-galactosidase (N460D) in complex with IPTG | Descriptor: | 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | Authors: | Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E. | Deposit date: | 2012-01-04 | Release date: | 2012-04-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability. Arch.Biochem.Biophys., 521, 2012
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5JS5
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![BU of 5js5 by Molmil](/molmil-images/mine/5js5) | Nitric oxide complex of the L16F mutant of cytochrome c prime from Alcaligenes xylosoxidans | Descriptor: | ASCORBIC ACID, Cytochrome c', HEME C, ... | Authors: | Kekilli, D, Strange, R.W, Hough, M.A. | Deposit date: | 2016-05-07 | Release date: | 2017-03-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Engineering proximal vs. distal heme-NO coordination via dinitrosyl dynamics: implications for NO sensor design. Chem Sci, 8, 2017
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5JUA
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5AR7
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![BU of 5ar7 by Molmil](/molmil-images/mine/5ar7) | RIP2 Kinase Catalytic Domain (1 - 310) complex with Biaryl Urea | Descriptor: | 1-(5-TERT-BUTYL-1,2-OXAZOL-3-YL)-3-(4-PYRIDIN-4-YLOXYPHENYL)UREA, RECEPTOR-INTERACTING SERINE/THREONINE-PROTEIN KINASE 2 | Authors: | Charnley, A.K, Convery, M.A, Lakdawala Shah, A, Jones, E, Hardwicke, P, Bridges, A, Votta, B.J, Gough, P.J, Marquis, R.W, Bertin, J, Casillas, L. | Deposit date: | 2015-09-24 | Release date: | 2015-10-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Crystal Structures of Human Rip2 Kinase Catalytic Domain Complexed with ATP-Competitive Inhibitors: Foundations for Understanding Inhibitor Selectivity. Bioorg.Med.Chem., 23, 2015
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2FAI
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![BU of 2fai by Molmil](/molmil-images/mine/2fai) | Human Estrogen Receptor Alpha Ligand-Binding Domain In Complex With OBCP-2M and A Glucocorticoid Receptor Interacting Protein 1 NR Box II Peptide | Descriptor: | 4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL, Estrogen receptor, Nuclear receptor coactivator 2 | Authors: | Rajan, S.S, Hsieh, R.W, Sharma, S.K, Greene, G.L. | Deposit date: | 2005-12-07 | Release date: | 2006-05-09 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity. J.Biol.Chem., 281, 2006
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3DDX
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![BU of 3ddx by Molmil](/molmil-images/mine/3ddx) | HK97 bacteriophage capsid Expansion Intermediate-II model | Descriptor: | Major capsid protein | Authors: | Lee, K.K, Gan, L, Conway, J.F, Hendrix, R.W, Steven, A.C, Johnson, J.E. | Deposit date: | 2008-06-06 | Release date: | 2008-11-04 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY | Cite: | Virus capsid expansion driven by the capture of mobile surface loops. Structure, 16, 2008
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3VDA
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![BU of 3vda by Molmil](/molmil-images/mine/3vda) | E. coli (lacZ) beta-galactosidase (N460T) | Descriptor: | Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | Authors: | Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E. | Deposit date: | 2012-01-04 | Release date: | 2012-04-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability. Arch.Biochem.Biophys., 521, 2012
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2HD1
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![BU of 2hd1 by Molmil](/molmil-images/mine/2hd1) | Crystal structure of PDE9 in complex with IBMX | Descriptor: | 3-ISOBUTYL-1-METHYLXANTHINE, MAGNESIUM ION, Phosphodiesterase 9A, ... | Authors: | Huai, Q, Wang, H, Zhang, W, Colman, R.W, Robinson, H, Ke, H. | Deposit date: | 2006-06-19 | Release date: | 2006-06-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Crystal structure of phosphodiesterase 9 shows orientation variation of inhibitor IBMX binding Proc.Natl.Acad.Sci.USA, 101, 2004
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2GTT
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![BU of 2gtt by Molmil](/molmil-images/mine/2gtt) | Crystal structure of the rabies virus nucleoprotein-RNA complex | Descriptor: | Nucleoprotein, PHOSPHATE ION, RNA (99-MER) | Authors: | Albertini, A.A.V, Wernimont, A.K, Muziol, T, Ravelli, R.B.G, Weissenhorn, W, Ruigrok, R.W.H. | Deposit date: | 2006-04-28 | Release date: | 2006-09-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.49 Å) | Cite: | Crystal Structure of the Rabies Virus Nucleoprotein-RNA Complex Science, 313, 2006
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3VDC
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![BU of 3vdc by Molmil](/molmil-images/mine/3vdc) | E. coli (lacZ) beta-galactosidase (N460T) in complex with IPTG | Descriptor: | 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | Authors: | Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E. | Deposit date: | 2012-01-04 | Release date: | 2012-04-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability. Arch.Biochem.Biophys., 521, 2012
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3VD9
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![BU of 3vd9 by Molmil](/molmil-images/mine/3vd9) | E. coli (lacZ) beta-galactosidase (N460S) in complex with IPTG | Descriptor: | 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | Authors: | Wheatley, R.W, Kappelhoff, J.C, Hahn, J.N, Dugdale, M.L, Dutkoski, M.J, Tamman, S.D, Fraser, M.E, Huber, R.E. | Deposit date: | 2012-01-04 | Release date: | 2012-04-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability. Arch.Biochem.Biophys., 521, 2012
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1K6A
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![BU of 1k6a by Molmil](/molmil-images/mine/1k6a) | Structural studies on the mobility in the active site of the Thermoascus aurantiacus xylanase I | Descriptor: | xylanase I | Authors: | Lo Leggio, L, Kalogiannis, S, Eckert, K, Teixeira, S.C.M, Bhat, M.K, Andrei, C, Pickersgill, R.W, Larsen, S. | Deposit date: | 2001-10-15 | Release date: | 2002-07-03 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.14 Å) | Cite: | Substrate specificity and subsite mobility in T. aurantiacus xylanase 10A. FEBS LETT., 509, 2001
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1KHO
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![BU of 1kho by Molmil](/molmil-images/mine/1kho) | Crystal Structure Analysis of Clostridium perfringens alpha-Toxin Isolated from Avian Strain SWCP | Descriptor: | ZINC ION, alpha-toxin | Authors: | Justin, N, Moss, D.S, Titball, R.W, Basak, A.K. | Deposit date: | 2001-11-30 | Release date: | 2002-06-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The first strain of Clostridium perfringens isolated from an avian source has an alpha-toxin with divergent structural and kinetic properties. Biochemistry, 41, 2002
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1LSC
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![BU of 1lsc by Molmil](/molmil-images/mine/1lsc) | |