1LX8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lx8 by Molmil](/molmil-images/mine/1lx8) | Regulation of directionality in bacteriophage lambda site-specific recombination: structure of the Xis protein | Descriptor: | Excisionase | Authors: | Sam, M.D, Papagiannis, C, Connolly, K.M, Corselli, L, Iwahara, J, Lee, J, Phillips, M, Wojciak, J.M, Johnson, R.C, Clubb, R.T. | Deposit date: | 2002-06-04 | Release date: | 2003-06-10 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Regulation of directionality in bacteriophage lambda site-specific recombination: structure of the Xis protein J.Mol.Biol., 324, 2002
|
|
1OSS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1oss by Molmil](/molmil-images/mine/1oss) | T190P STREPTOMYCES GRISEUS TRYPSIN IN COMPLEX WITH BENZAMIDINE | Descriptor: | BENZAMIDINE, CALCIUM ION, SULFATE ION, ... | Authors: | Page, M.J, Wong, S.L, Hewitt, J, Strynadka, N.C, MacGillivray, R.T. | Deposit date: | 2003-03-20 | Release date: | 2003-08-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Engineering the Primary Substrate Specificity of Streptomyces griseus Trypsin. Biochemistry, 42, 2003
|
|
1OS8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1os8 by Molmil](/molmil-images/mine/1os8) | RECOMBINANT STREPTOMYCES GRISEUS TRYPSIN | Descriptor: | CALCIUM ION, SULFATE ION, trypsin | Authors: | Page, M.J, Wong, S.L, Hewitt, J, Strynadka, N.C, MacGillivray, R.T. | Deposit date: | 2003-03-18 | Release date: | 2003-08-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Engineering the Primary Substrate Specificity of Streptomyces griseus Trypsin. Biochemistry, 42, 2003
|
|
1B28
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1b28 by Molmil](/molmil-images/mine/1b28) | ARC REPRESSOR MYL MUTANT FROM SALMONELLA BACTERIOPHAGE P22 | Descriptor: | PROTEIN (REGULATORY PROTEIN ARC) | Authors: | Rietveld, A.W.M, Nooren, I.M.A, Sauer, R.T, Kaptein, R, Boelens, R. | Deposit date: | 1998-12-05 | Release date: | 1999-11-03 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | The solution structure and dynamics of an Arc repressor mutant reveal premelting conformational changes related to DNA binding. Biochemistry, 38, 1999
|
|
1FM9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1fm9 by Molmil](/molmil-images/mine/1fm9) | THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN RXRALPHA AND PPARGAMMA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH 9-CIS RETINOIC ACID AND GI262570 AND CO-ACTIVATOR PEPTIDES. | Descriptor: | (9cis)-retinoic acid, 2-(2-BENZOYL-PHENYLAMINO)-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-PROPIONIC ACID, PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA, ... | Authors: | Gampe Jr, R.T, Montana, V.G, Lambert, M.H, Miller, A.B, Bledsoe, R.K, Milburn, M.V, Kliewer, S.A, Willson, T.M, Xu, H.E. | Deposit date: | 2000-08-16 | Release date: | 2001-02-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors. Mol.Cell, 5, 2000
|
|
1FM6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1fm6 by Molmil](/molmil-images/mine/1fm6) | THE 2.1 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF THE HETERODIMER OF THE HUMAN RXRALPHA AND PPARGAMMA LIGAND BINDING DOMAINS RESPECTIVELY BOUND WITH 9-CIS RETINOIC ACID AND ROSIGLITAZONE AND CO-ACTIVATOR PEPTIDES. | Descriptor: | (9cis)-retinoic acid, 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), ... | Authors: | Gampe Jr, R.T, Montana, V.G, Lambert, M.H, Miller, A.B, Bledsoe, R.K, Milburn, M.V, Kliewer, S.A, Willson, T.M, Xu, H.E. | Deposit date: | 2000-08-16 | Release date: | 2001-02-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors. Mol.Cell, 5, 2000
|
|
1G5Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1g5z by Molmil](/molmil-images/mine/1g5z) | CRYSTAL STRUCTURE OF LYME DISEASE ANTIGEN OUTER SURFACE PROTEIN C (OSPC) FROM BORRELIA BURGDORFERI STRAIN N40 | Descriptor: | OUTER SURFACE PROTEIN C | Authors: | Eicken, C, Sharma, V, Klabunde, T, Owens, R.T, Pikas, D.S, Hook, M, Sacchettini, J.C. | Deposit date: | 2000-11-02 | Release date: | 2001-04-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Crystal structure of Lyme disease antigen outer surface protein C from Borrelia burgdorferi. J.Biol.Chem., 276, 2001
|
|
1HPW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hpw by Molmil](/molmil-images/mine/1hpw) | STRUCTURE OF A PILIN MONOMER FROM PSEUDOMONAS AERUGINOSA: IMPLICATIONS FOR THE ASSEMBLY OF PILI. | Descriptor: | FIMBRIAL PROTEIN | Authors: | Keizer, D.W, Slupsky, C.M, Campbell, A.P, Irvin, R.T, Sykes, B.D. | Deposit date: | 2000-12-13 | Release date: | 2001-05-02 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Structure of a pilin monomer from Pseudomonas aeruginosa: implications for the assembly of pili. J.Biol.Chem., 276, 2001
|
|
1H00
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1h00 by Molmil](/molmil-images/mine/1h00) | CDK2 in complex with a disubstituted 4, 6-bis anilino pyrimidine CDK4 inhibitor | Descriptor: | (2R)-1-[4-({6-[(2,6-DIFLUOROPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL, (2S)-1-[4-({6-[(2,6-DIFLUOROPHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)PHENOXY]-3-(DIMETHYLAMINO)PROPAN-2-OL, CELL DIVISION PROTEIN KINASE 2 | Authors: | Beattie, J.F, Breault, G.A, Ellston, R.P.A, Green, S, Jewsbury, P.J, Midgley, C.J, Naven, R.T, Minshull, C.A, Pauptit, R.A, Tucker, J.A, Pease, J.E. | Deposit date: | 2002-06-10 | Release date: | 2003-07-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Cyclin-Dependent Kinase 4 Inhibitors as a Treatment for Cancer. Part 1: Identification and Optimisation of Substituted 4,6-Bis Anilino Pyrimidines Bioorg.Med.Chem.Lett., 13, 2003
|
|
1H07
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1h07 by Molmil](/molmil-images/mine/1h07) | CDK2 in complex with a disubstituted 4, 6-bis anilino pyrimidine CDK4 inhibitor | Descriptor: | ((2-BROMO-4-METHYLPHENYL){6-[(4-{[(2R)-3-(DIMETHYLAMINO)-2-HYDROXYPROPYL]OXY}PHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)ACETONITRILE, ((2-BROMO-4-METHYLPHENYL){6-[(4-{[(2S)-3-(DIMETHYLAMINO)-2-HYDROXYPROPYL]OXY}PHENYL)AMINO]PYRIMIDIN-4-YL}AMINO)ACETONITRILE, CELL DIVISION PROTEIN KINASE 2 | Authors: | Beattie, J.F, Breault, G.A, Ellston, R.P.A, Green, S, Jewsbury, P.J, Midgley, C.J, Naven, R.T, Minshull, C.A, Pauptit, R.A, Tucker, J.A, Pease, J.E. | Deposit date: | 2002-06-11 | Release date: | 2003-07-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Cyclin-Dependent Kinase 4 Inhibitors as a Treatment for Cancer. Part 1: Identification and Optimisation of Substituted 4,6-Bis Anilino Pyrimidines Bioorg.Med.Chem.Lett., 13, 2003
|
|
1IJA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ija by Molmil](/molmil-images/mine/1ija) | Structure of Sortase | Descriptor: | Sortase | Authors: | Ilangovan, U, Ton-That, H, Iwahara, J, Schneewind, O, Clubb, R.T. | Deposit date: | 2001-04-25 | Release date: | 2001-05-09 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of sortase, the transpeptidase that anchors proteins to the cell wall of Staphylococcus aureus. Proc.Natl.Acad.Sci.USA, 98, 2001
|
|
1G1S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1g1s by Molmil](/molmil-images/mine/1g1s) | P-SELECTIN LECTIN/EGF DOMAINS COMPLEXED WITH PSGL-1 PEPTIDE | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-[beta-D-galactopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-galactopyranose, P-SELECTIN, ... | Authors: | Somers, W.S, Camphausen, R.T. | Deposit date: | 2000-10-13 | Release date: | 2001-10-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Insights into the molecular basis of leukocyte tethering and rolling revealed by structures of P- and E-selectin bound to SLe(X) and PSGL-1. Cell(Cambridge,Mass.), 103, 2000
|
|
1G4D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1g4d by Molmil](/molmil-images/mine/1g4d) | |
1HQ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hq1 by Molmil](/molmil-images/mine/1hq1) | STRUCTURAL AND ENERGETIC ANALYSIS OF RNA RECOGNITION BY A UNIVERSALLY CONSERVED PROTEIN FROM THE SIGNAL RECOGNITION PARTICLE | Descriptor: | 4.5S RNA DOMAIN IV, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Batey, R.T, Sagar, M.B, Doudna, J.A. | Deposit date: | 2000-12-13 | Release date: | 2001-01-03 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Structural and energetic analysis of RNA recognition by a universally conserved protein from the signal recognition particle. J.Mol.Biol., 307, 2001
|
|
1IM1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1im1 by Molmil](/molmil-images/mine/1im1) | NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1, 20 STRUCTURES | Descriptor: | ALPHA-CONOTOXIN IM1 | Authors: | Rogers, J.P, Luginbuhl, P, Shen, G.S, Mccabe, R.T, Stevens, R.C, Wemmer, D.E. | Deposit date: | 1998-11-18 | Release date: | 1999-06-15 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | NMR solution structure of alpha-conotoxin ImI and comparison to other conotoxins specific for neuronal nicotinic acetylcholine receptors. Biochemistry, 38, 1999
|
|
1G1T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1g1t by Molmil](/molmil-images/mine/1g1t) | CRYSTAL STRUCTURE OF E-SELECTIN LECTIN/EGF DOMAINS COMPLEXED WITH SLEX | Descriptor: | CALCIUM ION, E-SELECTIN, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside | Authors: | Somers, W.S, Camphausen, R.T. | Deposit date: | 2000-10-13 | Release date: | 2001-10-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Insights into the molecular basis of leukocyte tethering and rolling revealed by structures of P- and E-selectin bound to SLe(X) and PSGL-1. Cell(Cambridge,Mass.), 103, 2000
|
|
1JN4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1jn4 by Molmil](/molmil-images/mine/1jn4) | The Crystal Structure of Ribonuclease A in complex with 2'-deoxyuridine 3'-pyrophosphate (P'-5') adenosine | Descriptor: | ADENOSINE-5'-[TRIHYDROGEN DIPHOSPHATE] P'-3'-ESTER WITH 2'-DEOXYURIDINE, Pancreatic Ribonuclease A | Authors: | Jardine, A.M, Leonidas, D.D, Jenkins, J.L, Park, C, Raines, R.T, Acharya, K.R, Shapiro, R. | Deposit date: | 2001-07-23 | Release date: | 2003-06-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Cleavage of 3',5'-Pyrophosphate-Linked Dinucleotides by Ribonuclease A and Angiogenin Biochemistry, 40, 2001
|
|
1G1R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1g1r by Molmil](/molmil-images/mine/1g1r) | Crystal structure of P-selectin lectin/EGF domains complexed with SLeX | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, CALCIUM ION, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]methyl 2-acetamido-2-deoxy-beta-D-glucopyranoside, ... | Authors: | Somers, W.S, Camphausen, R.T. | Deposit date: | 2000-10-13 | Release date: | 2001-10-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Insights into the molecular basis of leukocyte tethering and rolling revealed by structures of P- and E-selectin bound to SLe(X) and PSGL-1. Cell(Cambridge,Mass.), 103, 2000
|
|
1G1Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1g1q by Molmil](/molmil-images/mine/1g1q) | Crystal structure of P-selectin lectin/EGF domains | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, CALCIUM ION, P-SELECTIN | Authors: | Somers, W.S, Camphausen, R.T. | Deposit date: | 2000-10-13 | Release date: | 2001-10-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Insights into the molecular basis of leukocyte tethering and rolling revealed by structures of P- and E-selectin bound to SLe(X) and PSGL-1. Cell(Cambridge,Mass.), 103, 2000
|
|
1K5J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1k5j by Molmil](/molmil-images/mine/1k5j) | The Crystal Structure of Nucleoplasmin-Core | Descriptor: | Nucleoplasmin Core | Authors: | Dutta, S, Akey, I.V, Dingwall, C, Hartman, K.L, Laue, T, Nolte, R.T, Head, J.F, Akey, C.W. | Deposit date: | 2001-10-10 | Release date: | 2001-11-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The crystal structure of nucleoplasmin-core: implications for histone binding and nucleosome assembly. Mol.Cell, 8, 2001
|
|
1KJK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1kjk by Molmil](/molmil-images/mine/1kjk) | |
1BB8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1bb8 by Molmil](/molmil-images/mine/1bb8) | |
1DTG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dtg by Molmil](/molmil-images/mine/1dtg) | HUMAN TRANSFERRIN N-LOBE MUTANT H249E | Descriptor: | CARBONATE ION, FE (III) ION, TRANSFERRIN | Authors: | MacGillivray, R.T, Bewley, M.C, Smith, C.A, He, Q.Y, Mason, A.B. | Deposit date: | 2000-01-12 | Release date: | 2000-01-21 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Mutation of the iron ligand His 249 to Glu in the N-lobe of human transferrin abolishes the dilysine "trigger" but does not significantly affect iron release. Biochemistry, 39, 2000
|
|
1DUL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dul by Molmil](/molmil-images/mine/1dul) | STRUCTURE OF THE RIBONUCLEOPROTEIN CORE OF THE E. COLI SIGNAL RECOGNITION PARTICLE | Descriptor: | 4.5 S RNA DOMAIN IV, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Batey, R.T, Rambo, R.P, Lucast, L, Rha, B, Doudna, J.A. | Deposit date: | 2000-01-17 | Release date: | 2000-02-28 | Last modified: | 2020-10-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the ribonucleoprotein core of the signal recognition particle. Science, 287, 2000
|
|
1CLH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1clh by Molmil](/molmil-images/mine/1clh) | |