1DTG
HUMAN TRANSFERRIN N-LOBE MUTANT H249E
Summary for 1DTG
Entry DOI | 10.2210/pdb1dtg/pdb |
Descriptor | TRANSFERRIN, FE (III) ION, CARBONATE ION, ... (4 entities in total) |
Functional Keywords | iron transport, glycoprotein, metal-binding, polymorphism, 3d- structure, metal transport |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P02787 |
Total number of polymer chains | 1 |
Total formula weight | 36994.76 |
Authors | MacGillivray, R.T.,Bewley, M.C.,Smith, C.A.,He, Q.Y.,Mason, A.B. (deposition date: 2000-01-12, release date: 2000-01-21, Last modification date: 2021-11-03) |
Primary citation | MacGillivray, R.T.,Bewley, M.C.,Smith, C.A.,He, Q.Y.,Mason, A.B. Mutation of the iron ligand His 249 to Glu in the N-lobe of human transferrin abolishes the dilysine "trigger" but does not significantly affect iron release. Biochemistry, 39:1211-1216, 2000 Cited by PubMed: 10684598DOI: 10.1021/bi991522y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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