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PDB: 1595 件

5EAV
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Unliganded structure of the ornithine aminotransferase from Toxoplasma gondii
分子名称: DI(HYDROXYETHYL)ETHER, Ornithine aminotransferase, mitochondrial, ...
著者Filippova, E.V, Minasov, G, Flores, K, Le, H.V, Silverman, R.B, McLeod, R.L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2015-10-16
公開日2015-11-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Unliganded structure of the ornithine aminotransferase from Toxoplasma gondii
To Be Published
3NZQ
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Crystal Structure of Biosynthetic arginine decarboxylase ADC (SpeA) from Escherichia coli, Northeast Structural Genomics Consortium Target ER600
分子名称: Biosynthetic arginine decarboxylase, SULFATE ION
著者Forouhar, F, Lew, S, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Belote, R.L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
登録日2010-07-16
公開日2010-09-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of bacterial biosynthetic arginine decarboxylases.
Acta Crystallogr.,Sect.F, 66, 2010
5E5I
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Structure of the ornithine aminotransferase from Toxoplasma gondii in complex with inactivator
分子名称: 4-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]pent-4-enoic acid, 6-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]-4-oxidanylidene-hexanoic acid, DI(HYDROXYETHYL)ETHER, ...
著者Filippova, E.V, Minasov, G, Flores, K, Le, H.V, Silverman, R.B, McLeod, R.L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2015-10-08
公開日2016-10-19
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the ornithine aminotransferase from Toxoplasma gondii in complex with inactivator.
To Be Published
5E3K
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Crystal structure of the ornithine aminotransferase from Toxoplasma gondii ME49 in a complex with (S)-4-amino-5-fluoropentanoic acid
分子名称: 4-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]pent-4-enoic acid, Aminotransferase, CARBONATE ION, ...
著者Filippova, E.V, Minasov, G, Flores, K, Le, H.V, Silverman, R.B, McLeod, R.L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2015-10-02
公開日2016-10-26
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the ornithine aminotransferase from Toxoplasma gondii ME49 in a complex with (S)-4-amino-5-fluoropentanoic acid
To Be Published
1Z13
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Crystal Structure of Bovine Low Molecular Weight PTPase Complexed with Molybdate
分子名称: Low molecular weight phosphotyrosine protein phosphatase, MOLYBDATE ION
著者Zhang, M, Zhou, M, Van Etten, R.L, Stauffacher, C.V.
登録日2005-03-03
公開日2005-04-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of Bovine Low Molecular Weight Phosphotyrosyl Phosphatase Complexed with the Transition State Analog Vanadate
Biochemistry, 36, 1997
1ZFU
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Plectasin:A peptide antibiotic with therapeutic potential from a saprophytic fungus
分子名称: Plectasin
著者Mygind, P.H, Fischer, R.L, Schnorr, K, Hansen, M.T, Sonksen, C.P, Ludvigsen, S, Raventos, D, Buskov, S, Christensen, B, De Maria, L, Taboureau, O, Yaver, D, Elvig-Jorgensen, S.G, Sorensen, M.V, Christensen, B.E, Kjaerulf, S, Frimodt-Moller, N, Lehrer, R.I, Zasloff, M, Kristensen, H.H.
登録日2005-04-20
公開日2005-10-18
最終更新日2021-10-27
実験手法SOLUTION NMR
主引用文献Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus.
Nature, 437, 2005
1ZOX
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CLM-1 Mouse Myeloid Receptor Extracellular Domain
分子名称: CLM-1
著者Nelson, C.N, Burton, R.L, Fremont, D.H, Midwest Center for Structural Genomics (MCSG)
登録日2005-05-15
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of the Mouse CLM-1 Ectodomain
To be Published
1YWR
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Crystal Structure Analysis of inactive P38 kinase domain in complex with a Monocyclic Pyrazolone Inhibitor
分子名称: 4-(4-FLUOROPHENYL)-1-METHYL-5-(2-{[(1S)-1-PHENYLETHYL]AMINO}PYRIMIDIN-4-YL)-2-PIPERIDIN-4-YL-1,2-DIHYDRO-3H-PYRAZOL-3-ONE, Mitogen-activated protein kinase 14
著者Golebiowski, A, Townes, J.A, Laufersweiler, M.J, Brugel, T.A, Clark, M.P, Clark, C.M, Djung, J.F, Laughlin, S.K, Sabat, M.P, Bookland, R.G, Vanrens, J.C, De, B, Hsieh, L.C, Janusz, M.J, Walter, R.L, Webster, M.E, Mekel, M.J.
登録日2005-02-18
公開日2005-05-10
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The development of monocyclic pyrazolone based cytokine synthesis inhibitors.
Bioorg.Med.Chem.Lett., 15, 2005
2A92
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Crystal structure of lactate dehydrogenase from Plasmodium vivax: complex with NADH
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-lactate dehydrogenase
著者Chaikuad, A, Fairweather, V, Conners, R, Joseph-Horne, T, Turgut-Balik, D, Brady, R.L.
登録日2005-07-11
公開日2006-01-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structure of Lactate Dehydrogenase from Plasmodium vivax: Complexes with NADH and APADH.
Biochemistry, 44, 2005
8D12
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Crystal Structure of EcDsbA in a complex with 1-methyl-1H-pyrazol-4-amine
分子名称: 1-methyl-1H-pyrazol-4-amine, COPPER (II) ION, Thiol:disulfide interchange protein DsbA
著者Whitehouse, R.L, Ilyichova, O.V, Taylor, A.J.
登録日2022-05-26
公開日2022-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Fragment screening libraries for the identification of protein hot spots and their minimal binding pharmacophores.
Rsc Med Chem, 14, 2023
8CZM
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Crystal Structure of EcDsbA in a complex with 4-bromo-1H-pyrazole
分子名称: 4-bromo-1H-pyrazole, TRIETHYLENE GLYCOL, Thiol:disulfide interchange protein DsbA
著者Whitehouse, R.L, Ilyichova, O.V, Taylor, A.J.
登録日2022-05-25
公開日2022-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Fragment screening libraries for the identification of protein hot spots and their minimal binding pharmacophores.
Rsc Med Chem, 14, 2023
8DG0
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Crystal Structure of EcDsbA in a complex with Urea
分子名称: COPPER (II) ION, Thiol:disulfide interchange protein DsbA, UREA
著者Whitehouse, R.L, Ilyichova, O.V, Taylor, A.J.
登録日2022-06-23
公開日2022-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Fragment screening libraries for the identification of protein hot spots and their minimal binding pharmacophores.
Rsc Med Chem, 14, 2023
8CXD
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BU of 8cxd by Molmil
Crystal Structure of EcDsbA in a complex with phenylmethanol
分子名称: COPPER (II) ION, Thiol:disulfide interchange protein DsbA, phenylmethanol
著者Whitehouse, R.L, Ilyichova, O.V, Taylor, A.J.
登録日2022-05-20
公開日2022-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Fragment screening libraries for the identification of protein hot spots and their minimal binding pharmacophores.
Rsc Med Chem, 14, 2023
8CZN
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Crystal Structure of EcDsbA in a complex with 1H-pyrrole-3-carboxylic acid
分子名称: 1H-pyrrole-3-carboxylic acid, COPPER (II) ION, Thiol:disulfide interchange protein DsbA
著者Whitehouse, R.L, Ilyichova, O.V, Taylor, A.J.
登録日2022-05-25
公開日2022-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Fragment screening libraries for the identification of protein hot spots and their minimal binding pharmacophores.
Rsc Med Chem, 14, 2023
8DG1
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Crystal Structure of EcDsbA in a complex with DMSO
分子名称: COPPER (II) ION, DIMETHYL SULFOXIDE, Thiol:disulfide interchange protein DsbA
著者Whitehouse, R.L, Ilyichova, O.V, Taylor, A.J.
登録日2022-06-23
公開日2022-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Fragment screening libraries for the identification of protein hot spots and their minimal binding pharmacophores.
Rsc Med Chem, 14, 2023
8D11
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Crystal Structure of EcDsbA in a complex with 1-methyl-1H-pyrazol-5-amine
分子名称: 1-methyl-1H-pyrazol-5-amine, COPPER (II) ION, Thiol:disulfide interchange protein DsbA
著者Whitehouse, R.L, Ilyichova, O.V, Taylor, A.J.
登録日2022-05-26
公開日2022-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Fragment screening libraries for the identification of protein hot spots and their minimal binding pharmacophores.
Rsc Med Chem, 14, 2023
8CXE
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Crystal Structure of EcDsbA in a complex with 1H-imidazole
分子名称: IMIDAZOLE, Thiol:disulfide interchange protein DsbA
著者Whitehouse, R.L, Ilyichova, O.V, Taylor, A.J.
登録日2022-05-20
公開日2022-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Fragment screening libraries for the identification of protein hot spots and their minimal binding pharmacophores.
Rsc Med Chem, 14, 2023
8D10
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Crystal Structure of EcDsbA in a complex with (1-methyl-1H-pyrazol-5-yl)methanamine
分子名称: 1-(1-methyl-1H-pyrazol-5-yl)methanamine, COPPER (II) ION, Thiol:disulfide interchange protein DsbA
著者Whitehouse, R.L, Ilyichova, O.V, Taylor, A.J.
登録日2022-05-26
公開日2022-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Fragment screening libraries for the identification of protein hot spots and their minimal binding pharmacophores.
Rsc Med Chem, 14, 2023
8DG2
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Crystal Structure of EcDsbA in a complex with DMSO
分子名称: COPPER (II) ION, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Whitehouse, R.L, Ilyichova, O.V, Taylor, A.J.
登録日2022-06-23
公開日2022-12-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Fragment screening libraries for the identification of protein hot spots and their minimal binding pharmacophores.
Rsc Med Chem, 14, 2023
5E99
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Bovine Fab fragment F08_B11
分子名称: Fab F08_B11 heavy chain, Fab F08_B11 light chain
著者Stanfield, R.L, Wilson, I.A.
登録日2015-10-14
公開日2016-08-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies.
Sci Immunol, 1, 2016
8D4W
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Asymmetric ene-reduction of alpha,beta-unsaturated compounds using MSMEG_2850
分子名称: Cell entry (Mce) related family protein, DI(HYDROXYETHYL)ETHER, GLYCEROL
著者Kang, S.W, Frkic, R.L, Jackson, C.
登録日2022-06-02
公開日2023-01-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Asymmetric Ene-Reduction of alpha , beta-Unsaturated Compounds by F 420 -Dependent Oxidoreductases A Enzymes from Mycobacterium smegmatis .
Biochemistry, 62, 2023
2A94
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Structure of Plasmodium falciparum lactate dehydrogenase complexed to APADH.
分子名称: ACETYL PYRIDINE ADENINE DINUCLEOTIDE, REDUCED, L-lactate dehydrogenase
著者Chaikuad, A, Fairweather, V, Conners, R, Joseph-Horne, T, Turgut-Balik, D, Brady, R.L.
登録日2005-07-11
公開日2006-01-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of Lactate Dehydrogenase from Plasmodium vivax: Complexes with NADH and APADH.
Biochemistry, 44, 2005
8DAJ
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Structure and Biochemistry of a Promiscuous Thermophilic Polyhydroxybutyrate Depolymerase from Lihuaxuella thermophilia
分子名称: 1,2-ETHANEDIOL, Esterase, PHB depolymerase family, ...
著者Thomas, G.M, Quirk, S, Huard, D.J.E, Lieberman, R.L.
登録日2022-06-13
公開日2023-02-15
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Bioplastic degradation by a polyhydroxybutyrate depolymerase from a thermophilic soil bacterium.
Protein Sci., 31, 2022
5EQC
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Structure of the ornithine aminotransferase from Toxoplasma gondii crystallized in presence of oxidized glutathione reveals partial occupancy of PLP at the protein active site
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, ...
著者Filippova, E.V, Minasov, G, Flores, K, Le, H.V, Silverman, R.B, McLeod, R.L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2015-11-12
公開日2016-02-24
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the ornithine aminotransferase from Toxoplasma gondii crystallized in presence of oxidized glutathione reveals partial occupancy of PLP at the protein active site
To Be Published
5EZ8
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A de novo designed heptameric coiled coil CC-Hept-I-C-I
分子名称: CC-Hept-I-C-I
著者Burton, A.J, Brady, R.L, Woolfson, D.N.
登録日2015-11-26
公開日2016-07-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Installing hydrolytic activity into a completely de novo protein framework.
Nat.Chem., 8, 2016

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