5E3K

Crystal structure of the ornithine aminotransferase from Toxoplasma gondii ME49 in a complex with (S)-4-amino-5-fluoropentanoic acid

Summary for 5E3K

• Entry DOI: 10.2210/pdb5e3k/pdb
• Related: 4NOG 4ZLV 4ZWM 5DJ9
• Descriptor: Aminotransferase, 4-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]pent-4-enoic acid, SULFATE ION, ... (6 entities in total)
• Functional Keywords: inhibitor, complex, parasite, pyridoxal 5'-phosphate, structural genomics, center for structural genomics of infectious diseases, csgid, transferase
• Biological source: Toxoplasma gondii
• Total number of polymer chains: 2
• Total formula weight: 98647.79

Authors

Filippova, E.V.,Minasov, G.,Flores, K.,Le, H.V.,Silverman, R.B.,McLeod, R.L.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2015-10-02, release date: 2016-10-26, Last modification date: 2023-09-27)

• Primary citation: Filippova, E.V.,Minasov, G.,Flores, K.,Le, H.V.,Silverman, R.B.,McLeod, R.L.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID); Crystal structure of the ornithine aminotransferase from Toxoplasma gondii ME49 in a complex with (S)-4-amino-5-fluoropentanoic acid; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)