8CZM

Crystal Structure of EcDsbA in a complex with 4-bromo-1H-pyrazole

Summary for 8CZM

Entry DOI	10.2210/pdb8czm/pdb
Descriptor	Thiol:disulfide interchange protein DsbA, 4-bromo-1H-pyrazole, TRIETHYLENE GLYCOL, ... (4 entities in total)
Functional Keywords	disulfide oxidoreductase, redox protein, microfrag screening, oxidoreductase, fbdd, fragment, antimicrobial protein
Biological source	Escherichia coli K-12
Total number of polymer chains	2
Total formula weight	43342.06
Authors	Whitehouse, R.L.,Ilyichova, O.V.,Taylor, A.J. (deposition date: 2022-05-25, release date: 2022-12-07, Last modification date: 2023-10-25)
Primary citation	Whitehouse, R.L.,Alwan, W.S.,Ilyichova, O.V.,Taylor, A.J.,Chandrashekaran, I.R.,Mohanty, B.,Doak, B.C.,Scanlon, M.J. Fragment screening libraries for the identification of protein hot spots and their minimal binding pharmacophores. Rsc Med Chem, 14:135-143, 2023 Cited by PubMed: 36760747 DOI: 10.1039/d2md00253a PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation