1HI4
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![BU of 1hi4 by Molmil](/molmil-images/mine/1hi4) | Eosinophil-derived Neurotoxin (EDN) - Adenosien-3'-5'-Diphosphate Complex | Descriptor: | ADENOSINE-3'-5'-DIPHOSPHATE, EOSINOPHIL-DERIVED NEUROTOXIN | Authors: | Leonidas, D.D, Boix, E, Prill, R, Suzuki, M, Turton, R, Minson, K, Swaminathan, G.J, Youle, R.J, Acharya, K.R. | Deposit date: | 2001-01-02 | Release date: | 2001-05-31 | Last modified: | 2018-05-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mapping the Ribonucleolytic Active Site of Eosinophil-Derived Neurotoxin (Edn): High Resolution Crystal Structures of Edn Complexes with Adenylic Nucleotide Inhibitors J.Biol.Chem., 276, 2001
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1HI2
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![BU of 1hi2 by Molmil](/molmil-images/mine/1hi2) | Eosinophil-derived Neurotoxin (EDN) - Sulphate Complex | Descriptor: | EOSINOPHIL-DERIVED NEUROTOXIN, SULFATE ION | Authors: | Leonidas, D.D, Boix, E, Prill, R, Suzuki, M, Turton, R, Minson, K, Swaminathan, G.J, Youle, R.J, Acharya, K.R. | Deposit date: | 2001-01-02 | Release date: | 2001-05-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Mapping the Ribonucleolytic Active Site of Eosinophil-Derived Neurotoxin (Edn): High Resolution Crystal Structures of Edn Complexes with Adenylic Nucleotide Inhibitors J.Biol.Chem., 276, 2001
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1HI5
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![BU of 1hi5 by Molmil](/molmil-images/mine/1hi5) | Eosinophil-derived Neurotoxin (EDN) - Adenosine-5'-Diphosphate Complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, EOSINOPHIL-DERIVED NEUROTOXIN | Authors: | Leonidas, D.D, Boix, E, Prill, R, Suzuki, M, Turton, R, Minson, K, Swaminathan, G.J, Youle, R.J, Acharya, K.R. | Deposit date: | 2001-01-02 | Release date: | 2001-05-31 | Last modified: | 2018-05-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mapping the Ribonucleolytic Active Site of Eosinophil-Derived Neurotoxin (Edn): High Resolution Crystal Structures of Edn Complexes with Adenylic Nucleotide Inhibitors J.Biol.Chem., 276, 2001
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4E80
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![BU of 4e80 by Molmil](/molmil-images/mine/4e80) | Structural Basis for the Activity of a Cytoplasmic RNA Terminal U-transferase | Descriptor: | Poly(A) RNA polymerase protein cid1, URIDINE 5'-TRIPHOSPHATE | Authors: | Yates, L.A, Fleurdepine, S, Rissland, O.S, DeColibus, L, Harlos, K, Norbury, C.J, Gilbert, R.J.C. | Deposit date: | 2012-03-19 | Release date: | 2012-07-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.02 Å) | Cite: | Structural basis for the activity of a cytoplasmic RNA terminal uridylyl transferase. Nat.Struct.Mol.Biol., 19, 2012
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1IJD
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![BU of 1ijd by Molmil](/molmil-images/mine/1ijd) | Crystallographic Structure of the LH3 Complex from Rhodopseudomonas acidophila strain 7050 | Descriptor: | BACTERIOCHLOROPHYLL A, LIGHT-HARVESTING PROTEIN B-800/820, ALPHA CHAIN, ... | Authors: | McLuskey, K, Prince, S.M, Cogdell, R.J, Isaacs, N.W. | Deposit date: | 2001-04-25 | Release date: | 2001-10-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The crystallographic structure of the B800-820 LH3 light-harvesting complex from the purple bacteria Rhodopseudomonas acidophila strain 7050. Biochemistry, 40, 2001
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4ISE
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![BU of 4ise by Molmil](/molmil-images/mine/4ise) | Human glucokinase in complex with novel activator (2S)-3-cyclohexyl-2-(6-fluoro-4-oxoquinazolin-3(4H)-yl)-N-(1,3-thiazol-2-yl)propanamide | Descriptor: | (2S)-3-cyclohexyl-2-(6-fluoro-4-oxoquinazolin-3(4H)-yl)-N-(1,3-thiazol-2-yl)propanamide, Glucokinase, IODIDE ION, ... | Authors: | Hosfield, D, Skene, R.J. | Deposit date: | 2013-01-16 | Release date: | 2013-03-20 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Design, synthesis and SAR of novel glucokinase activators. Bioorg.Med.Chem.Lett., 23, 2013
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6GXT
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![BU of 6gxt by Molmil](/molmil-images/mine/6gxt) | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography: FAcD2052MS after reaction initiation | Descriptor: | Fluoroacetate dehalogenase, fluoroacetic acid | Authors: | Schulz, E.C, Mehrabi, P, Mueller-Werkmeister, H, Tellkamp, F, Stuart, W, Persch, E, De Gasparo, R, Diederich, F, Pai, E.F, Miller, R.J.D. | Deposit date: | 2018-06-27 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography. Nat. Methods, 15, 2018
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1IPP
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![BU of 1ipp by Molmil](/molmil-images/mine/1ipp) | HOMING ENDONUCLEASE/DNA COMPLEX | Descriptor: | CADMIUM ION, DNA (5'-D(*TP*TP*GP*AP*CP*TP*CP*TP*CP*TP*TP*AP*AP*GP*AP*GP*AP*GP*TP*CP*A)-3'), INTRON-ENCODED ENDONUCLEASE I-PPOI, ... | Authors: | Flick, K.E, Jurica, M.S, Monnat Jr, R.J, Stoddard, B.L. | Deposit date: | 1998-03-19 | Release date: | 1998-09-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | DNA binding and cleavage by the nuclear intron-encoded homing endonuclease I-PpoI. Nature, 394, 1998
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6GVD
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![BU of 6gvd by Molmil](/molmil-images/mine/6gvd) | Alpha-galactosidase from Thermotoga maritima in complex with cyclohexene-based carbasugar mimic of galactose | Descriptor: | (1~{S},2~{S},3~{S},4~{S})-5-(hydroxymethyl)cyclohex-5-ene-1,2,3,4-tetrol, Alpha-galactosidase, MAGNESIUM ION, ... | Authors: | Gloster, T.M, Pengelly, R.J. | Deposit date: | 2018-06-20 | Release date: | 2018-08-22 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level. Nat Commun, 9, 2018
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6GXL
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![BU of 6gxl by Molmil](/molmil-images/mine/6gxl) | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography: RADDAM2 | Descriptor: | Fluoroacetate dehalogenase | Authors: | Schulz, E.C, Mehrabi, P, Mueller-Werkmeister, H, Tellkamp, F, Stuart, W, Persch, E, De Gasparo, R, Diederich, F, Pai, E.F, Miller, R.J.D. | Deposit date: | 2018-06-27 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography. Nat. Methods, 15, 2018
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5FOL
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![BU of 5fol by Molmil](/molmil-images/mine/5fol) | Crystal structure of the Cryptosporidium muris cytosolic leucyl-tRNA synthetase editing domain complex with a post-transfer editing analogue of isoeucine (Ile2AA) | Descriptor: | 2'-(L-ISOLEUCYL)AMINO-2'-DEOXYADENOSINE, LEUCYL-TRNA SYNTHETASE, PHOSPHATE ION | Authors: | Palencia, A, Liu, R.J, Lukarska, M, Gut, J, Bougdour, A, Touquet, B, Wang, E.D, Alley, M.R.K, Rosenthal, P.J, Hakimi, M.A, Cusack, S. | Deposit date: | 2015-11-24 | Release date: | 2016-08-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Cryptosporidium and Toxoplasma Parasites are Inhibited by a Benzoxaborole Targeting Leucyl-tRNA Synthetase. Antimicrob.Agents Chemother., 60, 2016
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5FOM
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![BU of 5fom by Molmil](/molmil-images/mine/5fom) | Crystal structure of the Cryptosporidium muris cytosolic leucyl-tRNA synthetase editing domain complex with the adduct AMP-AN6426 | Descriptor: | 4-Chloro-3-aminomethyl-7-[ethoxy]-3H-benzo[C][1,2]oxaborol-1-ol modified adenosine, LEUCYL-TRNA SYNTHETASE, PHOSPHATE ION | Authors: | Palencia, A, Liu, R.J, Lukarska, M, Gut, J, Bougdour, A, Touquet, B, Wang, E.D, Alley, M.R.K, Rosenthal, P.J, Hakimi, M.A, Cusack, S. | Deposit date: | 2015-11-24 | Release date: | 2016-08-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Cryptosporidium and Toxoplasma Parasites are Inhibited by a Benzoxaborole Targeting Leucyl-tRNA Synthetase. Antimicrob.Agents Chemother., 60, 2016
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1DVF
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![BU of 1dvf by Molmil](/molmil-images/mine/1dvf) | IDIOTOPIC ANTIBODY D1.3 FV FRAGMENT-ANTIIDIOTOPIC ANTIBODY E5.2 FV FRAGMENT COMPLEX | Descriptor: | FV D1.3, FV E5.2, ZINC ION | Authors: | Braden, B.C, Fields, B.A, Ysern, X, Dall'Acqua, W, Goldbaum, F.A, Poljak, R.J, Mariuzza, R.A. | Deposit date: | 1996-04-13 | Release date: | 1996-08-17 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of an Fv-Fv idiotope-anti-idiotope complex at 1.9 A resolution. J.Mol.Biol., 264, 1996
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4Z9C
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![BU of 4z9c by Molmil](/molmil-images/mine/4z9c) | EcPltAB Oxidized | Descriptor: | PHOSPHATE ION, Pertussis toxin-like subunit ArtA, Subtilase cytotoxin subunit B-like protein | Authors: | Littler, D.R, Johnson, M.D, Summers, R.J, Schembri, M.A, Rossjohn, J, Beddoe, T. | Deposit date: | 2015-04-10 | Release date: | 2016-10-12 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structure and function analyses of a pertussis-like toxin from pathogenic Escherichia coli reveal a distinct mechanism of inhibition of trimeric G proteins. J. Biol. Chem., 2017
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6GXF
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![BU of 6gxf by Molmil](/molmil-images/mine/6gxf) | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography: RADDAM1 | Descriptor: | Fluoroacetate dehalogenase | Authors: | Schulz, E.C, Mehrabi, P, Mueller-Werkmeister, H, Tellkamp, F, Stuart, W, Persch, E, De Gasparo, R, Diederich, F, Pai, E.F, Miller, R.J.D. | Deposit date: | 2018-06-27 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography. Nat. Methods, 15, 2018
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1EWM
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![BU of 1ewm by Molmil](/molmil-images/mine/1ewm) | |
1EWO
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![BU of 1ewo by Molmil](/molmil-images/mine/1ewo) | |
6GXH
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![BU of 6gxh by Molmil](/molmil-images/mine/6gxh) | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography: FAcD 0MS after reaction initiation | Descriptor: | Fluoroacetate dehalogenase | Authors: | Schulz, E.C, Mehrabi, P, Mueller-Werkmeister, H, Tellkamp, F, Stuart, W, Persch, E, De Gasparo, R, Diederich, F, Pai, E.F, Miller, R.J.D. | Deposit date: | 2018-06-27 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.802 Å) | Cite: | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography. Nat. Methods, 15, 2018
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1E14
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![BU of 1e14 by Molmil](/molmil-images/mine/1e14) | PHOTOSYNTHETIC REACTION CENTER MUTANT WITH PHE M197 REPLACED WITH ARG (CHAIN M, FM197R) AND GLY M203 REPLACED WITH ASP (CHAIN M, GM203D) | Descriptor: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ... | Authors: | Fyfe, P.K, Ridge, J.P, McAuley, K.E, Cogdell, R.J, Isaacs, N.W, Jones, M.R. | Deposit date: | 2000-04-18 | Release date: | 2000-06-02 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Consequences of the Replacement of Glycine M203 with Aspartic Acid in the Reaction Center from Rhodobacter Sphaeroides. Biochemistry, 39, 2000
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4J52
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![BU of 4j52 by Molmil](/molmil-images/mine/4j52) | Crystal structure of PLK1 in complex with a pyrimidodiazepinone inhibitor | Descriptor: | 4-{[(7R)-9-cyclopentyl-7-ethenyl-7-fluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl]amino}-3-methoxy-N-(4-methylpiperazin-1-yl)benzamide, ACETATE ION, Serine/threonine-protein kinase PLK1, ... | Authors: | Hosfield, D.J, Skene, R.J. | Deposit date: | 2013-02-07 | Release date: | 2013-05-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Discovery of TAK-960: An orally available small molecule inhibitor of polo-like kinase 1 (PLK1). Bioorg.Med.Chem.Lett., 23, 2013
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1HD9
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![BU of 1hd9 by Molmil](/molmil-images/mine/1hd9) | The Bowman-Birk Inhibitor Reactive Site Loop Sequence Represents an Independent Structural Beta-Hairpin Motif | Descriptor: | BOWMAN-BIRK INHIBITOR DERIVED PEPTIDE | Authors: | Brauer, A.B.E, Kelly, G, McBride, J.D, Cooke, R.M, Matthews, S.J, Leatherbarrow, R.J. | Deposit date: | 2000-11-13 | Release date: | 2001-03-29 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | The Bowman-Birk Inhibitor Reactive Site Loop Sequence Represents an Independent Structural Beta-Hairpin Motif J.Mol.Biol., 306, 2001
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6GTA
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![BU of 6gta by Molmil](/molmil-images/mine/6gta) | Alpha-galactosidase mutant D378A from Thermotoga maritima in complex with intact cyclohexene-based carbasugar mimic of galactose with 3,5 difluorophenyl leaving group | Descriptor: | (1~{R},2~{S},3~{S},6~{S})-6-[3,5-bis(fluoranyl)phenoxy]-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triol, Alpha-galactosidase, MAGNESIUM ION, ... | Authors: | Gloster, T.M, Pengelly, R.J. | Deposit date: | 2018-06-17 | Release date: | 2018-08-22 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level. Nat Commun, 9, 2018
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5FON
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![BU of 5fon by Molmil](/molmil-images/mine/5fon) | Crystal structure of the Cryptosporidium muris cytosolic leucyl-tRNA synthetase editing domain (apo structure) | Descriptor: | LEUCYL-TRNA SYNTHETASE | Authors: | Palencia, A, Liu, R.J, Lukarska, M, Gut, J, Bougdour, A, Touquet, B, Wang, E.D, Alley, M.R.K, Rosenthal, P.J, Hakimi, M.A, Cusack, S. | Deposit date: | 2015-11-24 | Release date: | 2016-08-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Cryptosporidium and Toxoplasma Parasites are Inhibited by a Benzoxaborole Targeting Leucyl-tRNA Synthetase. Antimicrob.Agents Chemother., 60, 2016
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1HI3
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![BU of 1hi3 by Molmil](/molmil-images/mine/1hi3) | Eosinophil-derived Neurotoxin (EDN) - Adenosine 2'-5'-Diphosphate Complex | Descriptor: | ADENOSINE-2'-5'-DIPHOSPHATE, EOSINOPHIL-DERIVED NEUROTOXIN | Authors: | Leonidas, D.D, Boix, E, Prill, R, Suzuki, M, Turton, R, Minson, K, Swaminathan, G.J, Youle, R.J, Acharya, K.R. | Deposit date: | 2001-01-02 | Release date: | 2001-05-31 | Last modified: | 2018-05-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mapping the Ribonucleolytic Active Site of Eosinophil-Derived Neurotoxin (Edn): High Resolution Crystal Structures of Edn Complexes with Adenylic Nucleotide Inhibitors J.Biol.Chem., 276, 2001
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4ZDM
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![BU of 4zdm by Molmil](/molmil-images/mine/4zdm) | Pleurobrachia bachei iGluR3 LBD Glycine Complex | Descriptor: | GLYCINE, Glutamate receptor kainate-like protein, SODIUM ION, ... | Authors: | Grey, R.J, Mayer, M.L. | Deposit date: | 2015-04-17 | Release date: | 2015-10-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Glycine activated ion channel subunits encoded by ctenophore glutamate receptor genes. Proc.Natl.Acad.Sci.USA, 112, 2015
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