6GVD
Alpha-galactosidase from Thermotoga maritima in complex with cyclohexene-based carbasugar mimic of galactose
Summary for 6GVD
| Entry DOI | 10.2210/pdb6gvd/pdb |
| Related | 6GTA |
| Descriptor | Alpha-galactosidase, SULFATE ION, MAGNESIUM ION, ... (5 entities in total) |
| Functional Keywords | glycoside hydrolase, galactosidase, carbohydrate processing enzyme, inhibitor, hydrolase |
| Biological source | Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) |
| Total number of polymer chains | 1 |
| Total formula weight | 66639.30 |
| Authors | Gloster, T.M.,Pengelly, R.J. (deposition date: 2018-06-20, release date: 2018-08-22, Last modification date: 2024-01-17) |
| Primary citation | Ren, W.,Pengelly, R.,Farren-Dai, M.,Shamsi Kazem Abadi, S.,Oehler, V.,Akintola, O.,Draper, J.,Meanwell, M.,Chakladar, S.,Swiderek, K.,Moliner, V.,Britton, R.,Gloster, T.M.,Bennet, A.J. Revealing the mechanism for covalent inhibition of glycoside hydrolases by carbasugars at an atomic level. Nat Commun, 9:3243-3243, 2018 Cited by PubMed: 30104598DOI: 10.1038/s41467-018-05702-7 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.22 Å) |
Structure validation
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