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PDB: 2308 件

8UF2
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Apo SOS2 crystal structure in P1 space group
分子名称: SULFATE ION, Son of sevenless homolog 2
著者Gunn, R.J, Lawson, J.D.
登録日2023-10-03
公開日2024-01-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography.
J.Med.Chem., 67, 2024
8UH0
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BU of 8uh0 by Molmil
SOS2 co-crystal structure with fragment bound (compound 10)
分子名称: 8-hydroxyquinoline-2-carbonitrile, Son of sevenless homolog 2
著者Gunn, R.J, Lawson, J.D.
登録日2023-10-06
公開日2024-01-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography.
J.Med.Chem., 67, 2024
8UPT
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BU of 8upt by Molmil
Candidatus Methanomethylophilus alvus tRNAPyl in A-site of ribosome
分子名称: RNA (71-MER)
著者Krahn, N, Zhang, J, Melnikov, S.V, Tharp, J.M, Villa, A, Patel, A, Howard, R.J, Gabir, H, Patel, T.R, Stetefeld, J, Puglisi, J, Soll, D.
登録日2023-10-23
公開日2024-01-10
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献tRNA shape is an identity element for an archaeal pyrrolysyl-tRNA synthetase from the human gut.
Nucleic Acids Res., 52, 2024
8UC9
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BU of 8uc9 by Molmil
SOS2 co-crystal structure with fragment bound (compound 9)
分子名称: 7-chloroquinolin-4-amine, Son of sevenless homolog 2
著者Gunn, R.J, Lawson, J.D.
登録日2023-09-26
公開日2024-01-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography.
J.Med.Chem., 67, 2024
8UWF
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BU of 8uwf by Molmil
NMR structure of the funnel-web spider toxin Hc3a
分子名称: Pi-Hexatoxin-Hc1b_1
著者Budusan, E, Payne, C.D, Gonzalez, T.I, Clark, R.J, Rosengren, K.J, Rash, L.D, Cristofori-Armstrong, B.
登録日2023-11-06
公開日2024-03-13
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The funnel-web spider venom derived single knot peptide Hc3a modulates acid-sensing ion channel 1a desensitisation.
Biochem Pharmacol, 2024
8FU3
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BU of 8fu3 by Molmil
Structure Of Respiratory Syncytial Virus Polymerase with Novel Non-Nucleoside Inhibitor
分子名称: 8-methoxy-3-methyl-N-{(2S)-3,3,3-trifluoro-2-[5-fluoro-6-(4-fluorophenyl)-4-(2-hydroxypropan-2-yl)pyridin-2-yl]-2-hydroxypropyl}cinnoline-6-carboxamide, Phosphoprotein, RNA-directed RNA polymerase L
著者Yu, X, Abeywickrema, P, Bonneux, B, Behera, I, Jacoby, E, Fung, A, Adhikary, S, Bhaumik, A, Carbajo, R.J, Bruyn, S.D, Miller, R, Patrick, A, Pham, Q, Piassek, M, Verheyen, N, Shareef, A, Sutto-Ortiz, P, Ysebaert, N, Vlijmen, H.V, Jonckers, T.H.M, Herschke, F, McLellan, J.S, Decroly, E, Fearns, R, Grosse, S, Roymans, D, Sharma, S, Rigaux, P, Jin, Z.
登録日2023-01-16
公開日2023-11-01
実験手法ELECTRON MICROSCOPY (2.88 Å)
主引用文献Structural and mechanistic insights into the inhibition of respiratory syncytial virus polymerase by a non-nucleoside inhibitor.
Commun Biol, 6, 2023
6F90
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BU of 6f90 by Molmil
Structure of the family GH92 alpha-mannosidase BT3130 from Bacteroides thetaiotaomicron in complex with Mannoimidazole (ManI)
分子名称: (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, Alpha-1,2-mannosidase, putative, ...
著者Thompson, A.J, Spears, R.J, Zhu, Y, Suits, M.D.L, Williams, S.J, Gilbert, H.J, Davies, G.J.
登録日2017-12-13
公開日2018-05-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Bacteroides thetaiotaomicron generates diverse alpha-mannosidase activities through subtle evolution of a distal substrate-binding motif.
Acta Crystallogr D Struct Biol, 74, 2018
8FXP
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BU of 8fxp by Molmil
Structure of capsid of Agrobacterium phage Milano
分子名称: Linking protein 1, gp16, Linking protein 2, ...
著者Sonani, R.R, Wang, F, Esteves, N.C, Kelly, R.J, Sebastian, A, Kreutzberger, M.A.B, Leiman, P.G, Scharf, B.E, Egelman, E.H.
登録日2023-01-25
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (4.04 Å)
主引用文献Neck and capsid architecture of the robust Agrobacterium phage Milano.
Commun Biol, 6, 2023
8FWB
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BU of 8fwb by Molmil
Portal assembly of Agrobacterium phage Milano
分子名称: Portal protein, gp7
著者Sonani, R.R, Wang, F, Esteves, N.C, Kelly, R.J, Sebastian, A, Kreutzberger, M.A.B, Leiman, P.G, Scharf, B.E, Egelman, E.H.
登録日2023-01-20
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Neck and capsid architecture of the robust Agrobacterium phage Milano.
Commun Biol, 6, 2023
8FXR
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BU of 8fxr by Molmil
Structure of neck with portal vertex of capsid of Agrobacterium phage Milano
分子名称: Collar sheath protein, gp13, Linking protein 1, ...
著者Sonani, R.R, Wang, F, Esteves, N.C, Kelly, R.J, Sebastian, A, Kreutzberger, M.A.B, Leiman, P.G, Scharf, B.E, Egelman, E.H.
登録日2023-01-25
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Neck and capsid architecture of the robust Agrobacterium phage Milano.
Commun Biol, 6, 2023
8FWG
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BU of 8fwg by Molmil
Structure of neck and portal vertex of Agrobacterium phage Milano, C5 symmetry
分子名称: Collar sheath protein, gp13, Linking protein 1, ...
著者Sonani, R.R, Wang, F, Esteves, N.C, Kelly, R.J, Sebastian, A, Kreutzberger, M.A.B, Leiman, P.G, Scharf, B.E, Egelman, E.H.
登録日2023-01-22
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Neck and capsid architecture of the robust Agrobacterium phage Milano.
Commun Biol, 6, 2023
8FWM
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BU of 8fwm by Molmil
Structure of tail-neck junction of Agrobacterium phage Milano
分子名称: Collar sheath protein, gp13, Tail sheath protein, ...
著者Sonani, R.R, Wang, F, Esteves, N.C, Kelly, R.J, Sebastian, A, Kreutzberger, M.A.B, Leiman, P.G, Scharf, B.E, Egelman, E.H.
登録日2023-01-23
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Neck and capsid architecture of the robust Agrobacterium phage Milano.
Commun Biol, 6, 2023
8FWC
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BU of 8fwc by Molmil
Collar sheath structure of Agrobacterium phage Milano
分子名称: Collar sheath protein, gp13
著者Sonani, R.R, Wang, F, Esteves, N.C, Kelly, R.J, Sebastian, A, Kreutzberger, M.A.B, Leiman, P.G, Scharf, B.E, Egelman, E.H.
登録日2023-01-20
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.96 Å)
主引用文献Neck and capsid architecture of the robust Agrobacterium phage Milano.
Commun Biol, 6, 2023
8FWE
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BU of 8fwe by Molmil
Neck structure of Agrobacterium phage Milano, C3 symmetry
分子名称: Collar sheath protein, gp13, Neck 1 protein, ...
著者Sonani, R.R, Wang, F, Esteves, N.C, Kelly, R.J, Sebastian, A, Kreutzberger, M.A.B, Leiman, P.G, Scharf, B.E, Egelman, E.H.
登録日2023-01-21
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Neck and capsid architecture of the robust Agrobacterium phage Milano.
Commun Biol, 6, 2023
6X9O
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BU of 6x9o by Molmil
High resolution cryoEM structure of huntingtin in complex with HAP40
分子名称: 40-kDa huntingtin-associated protein, Huntingtin
著者Harding, R.J, Deme, J.C, Lea, S.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC)
登録日2020-06-03
公開日2020-06-17
最終更新日2022-03-30
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1.
Commun Biol, 4, 2021
8FQC
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BU of 8fqc by Molmil
Structure of baseplate with receptor binding complex of Agrobacterium phage Milano
分子名称: Baseplate Centerpiece, gp25, Baseplate Central Spike, ...
著者Sonani, R.R, Leiman, P.G, Wang, F, Kreutzberger, M.A.B, Sebastian, A, Esteves, N.C, Kelly, R.J, Scharf, B, Egelman, E.H.
登録日2023-01-05
公開日2024-01-31
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献An extensive disulfide bond network prevents tail contraction in Agrobacterium tumefaciens phage Milano.
Nat Commun, 15, 2024
8FOU
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BU of 8fou by Molmil
Structure of Agrobacterium tumefaciens bacteriophage Milano contracted tail-tube
分子名称: Virion-associated protein
著者Sonani, R.R, Leiman, P.G, Wang, F, Kreutzberger, M.A.B, Sebastian, A, Esteves, N.C, Kelly, R.J, Scharf, B, Egelman, E.H.
登録日2023-01-03
公開日2024-01-17
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献An extensive disulfide bond network prevents tail contraction in Agrobacterium tumefaciens phage Milano.
Nat Commun, 15, 2024
8FOY
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BU of 8foy by Molmil
Structure of Agrobacterium tumefaciens bacteriophage Milano contracted tail-sheath
分子名称: Tail sheath protein
著者Sonani, R.R, Leiman, P.G, Wang, F, Kreutzberger, M.A.B, Sebastian, A, Esteves, N.C, Kelly, R.J, Scharf, B, Egelman, E.H.
登録日2023-01-03
公開日2024-01-17
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献An extensive disulfide bond network prevents tail contraction in Agrobacterium tumefaciens phage Milano.
Nat Commun, 15, 2024
8WBU
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BU of 8wbu by Molmil
The crystal structure of circular mannose with mutant H247F of the cellobiose 2-epimerase from Caldicellulosiruptor saccharolyticus
分子名称: Cellobiose 2-epimerase, beta-D-mannopyranose
著者Yang, R.J, Feng, Y.H.
登録日2023-09-10
公開日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The crystal structure of circular mannose with mutant H247F of the cellobiose 2-epimerase from Caldicellulosiruptor saccharolyticus
To Be Published
8WBV
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BU of 8wbv by Molmil
The crystal structure of linear mannose with mutant H247F of the cellobiose 2-epimerase from Caldicellulosiruptor saccharolyticus
分子名称: 1,2-ETHANEDIOL, Cellobiose 2-epimerase, D-mannose, ...
著者Yang, R.J, Feng, Y.H.
登録日2023-09-10
公開日2023-10-25
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The crystal structure of linear mannose with mutant H247F of the cellobiose 2-epimerase from Caldicellulosiruptor saccharolyticus
To Be Published
8FOP
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BU of 8fop by Molmil
Structure of Agrobacterium tumefaciens bacteriophage Milano curved tail
分子名称: Tail sheath protein, Virion-associated protein
著者Sonani, R.R, Leiman, P.G, Wang, F, Kreutzberger, M.A.B, Sebastian, A, Esteves, N.C, Kelly, R.J, Scharf, B, Egelman, E.H.
登録日2023-01-03
公開日2024-01-17
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献An extensive disulfide bond network prevents tail contraction in Agrobacterium tumefaciens phage Milano.
Nat Commun, 15, 2024
6F92
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BU of 6f92 by Molmil
Structure of the family GH92 alpha-mannosidase BT3965 from Bacteroides thetaiotaomicron in complex with Mannoimidazole (ManI)
分子名称: (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, 1,2-ETHANEDIOL, CALCIUM ION, ...
著者Thompson, A.J, Spears, R.J, Zhu, Y, Suits, M.D.L, Williams, S.J, Gilbert, H.J, Davies, G.J.
登録日2017-12-13
公開日2018-05-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Bacteroides thetaiotaomicron generates diverse alpha-mannosidase activities through subtle evolution of a distal substrate-binding motif.
Acta Crystallogr D Struct Biol, 74, 2018
6X3T
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BU of 6x3t by Molmil
Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus propofol
分子名称: 2,6-BIS(1-METHYLETHYL)PHENOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Kim, J.J, Gharpure, A, Teng, J, Zhuang, Y, Howard, R.J, Zhu, S, Noviello, C.M, Walsh, R.M, Lindahl, E, Hibbs, R.E.
登録日2020-05-21
公開日2020-09-09
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.55 Å)
主引用文献Shared structural mechanisms of general anaesthetics and benzodiazepines.
Nature, 585, 2020
5A7G
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BU of 5a7g by Molmil
Comparison of the structure and activity of glycosylated and aglycosylated Human Carboxylesterase 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, LIVER CARBOXYLESTERASE 1
著者Arena de Souza, V, Scott, D.J, Charlton, M, Walsh, M.A, Owen, R.J.
登録日2015-07-04
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Comparison of the Structure and Activity of Glycosylated and Aglycosylated Human Carboxylesterase 1.
Plos One, 10, 2015
6F8Z
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BU of 6f8z by Molmil
Structure of the family GH92 alpha-mannosidase BT3130 from Bacteroides thetaiotaomicron
分子名称: 1,2-ETHANEDIOL, Alpha-1,2-mannosidase, putative, ...
著者Thompson, A.J, Spears, R.J, Zhu, Y, Suits, M.D.L, Williams, S.J, Gilbert, H.J, Davies, G.J.
登録日2017-12-13
公開日2018-05-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Bacteroides thetaiotaomicron generates diverse alpha-mannosidase activities through subtle evolution of a distal substrate-binding motif.
Acta Crystallogr D Struct Biol, 74, 2018

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件を2024-07-10に公開中

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