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PDB: 2325 件

1PLP
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SOLUTION STRUCTURE OF THE CYTOPLASMIC DOMAIN OF PHOSPHOLAMBAN
分子名称: PHOSPHOLAMBAN
著者Mortishire-Smith, R.J, Pitzenberger, S.M, Burke, C.J, Middaugh, C.R, Garsky, V.M, Johnson, R.G.
登録日1995-05-01
公開日1995-07-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the cytoplasmic domain of phopholamban: phosphorylation leads to a local perturbation in secondary structure.
Biochemistry, 34, 1995
1POU
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THE SOLUTION STRUCTURE OF THE OCT-1 POU-SPECIFIC DOMAIN REVEALS A STRIKING SIMILARITY TO THE BACTERIOPHAGE LAMBDA REPRESSOR DNA-BINDING DOMAIN
分子名称: OCT-1
著者Assa-Munt, N, Mortishire-Smith, R.J, Aurora, R, Herr, W, Wright, P.E.
登録日1993-06-14
公開日1994-10-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The solution structure of the Oct-1 POU-specific domain reveals a striking similarity to the bacteriophage lambda repressor DNA-binding domain.
Cell(Cambridge,Mass.), 73, 1993
5C23
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Parkin (S65DUblR0RBR)
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ...
著者Kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H.
登録日2015-06-15
公開日2015-07-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
8TOR
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ACE2-peptide 2 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Christie, M, Payne, R.J.
登録日2023-08-03
公開日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity.
Acs Chem.Biol., 19, 2024
8TOT
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ACE2-peptide2 complex crystal form 2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Christie, M, Payne, R.J.
登録日2023-08-03
公開日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity.
Acs Chem.Biol., 19, 2024
8TOU
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ACE2-peptide 2 complex crystal form 3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
著者Franck, C, Payne, R.J, Christie, M.
登録日2023-08-04
公開日2024-02-07
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity.
Acs Chem.Biol., 19, 2024
5C8J
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A YidC-like protein in the archaeal plasma membrane
分子名称: Antibody fragment, heavy chain, light chain, ...
著者Borowska, M.T, Dominik, P.K, Anghel, S.A, Kossiakoff, A.A, Keenan, R.J.
登録日2015-06-25
公開日2015-09-02
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (3.502 Å)
主引用文献A YidC-like Protein in the Archaeal Plasma Membrane.
Structure, 23, 2015
5MWF
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Human Jagged2 C2-EGF2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Suckling, R.J, Handford, P.A, Lea, S.M.
登録日2017-01-18
公開日2017-06-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.
EMBO J., 36, 2017
5CMI
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GTA mutant without mercury - E303D
分子名称: Histo-blood group ABO system transferase
著者Gagnon, S.M.L, Blackler, R.J.
登録日2015-07-16
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Glycosyltransfer in mutants of putative catalytic residue Glu303 of the human ABO(H) A and B blood group glycosyltransferases GTA and GTB proceeds through a labile active site.
Glycobiology, 27, 2017
5MVX
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Human DLL4 C2-EGF3
分子名称: Delta-like protein 4, alpha-L-fucopyranose
著者Suckling, R.J, Handford, P.A, Lea, S.M.
登録日2017-01-17
公開日2017-06-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.
EMBO J., 36, 2017
5MW7
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Human Jagged2 C2-EGF3
分子名称: Protein jagged-2, alpha-L-fucopyranose
著者Suckling, R.J, Handford, P.A, Lea, S.M.
登録日2017-01-18
公開日2017-06-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.
EMBO J., 36, 2017
5MW5
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Human Jagged2 C2-EGF2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Protein jagged-2
著者Suckling, R.J, Handford, P.A, Lea, S.M.
登録日2017-01-18
公開日2017-06-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.
EMBO J., 36, 2017
5MWB
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Human Notch-2 EGF11-13
分子名称: CALCIUM ION, Neurogenic locus notch homolog protein 2, alpha-L-fucopyranose, ...
著者Suckling, R.J, Handford, P.A, Lea, S.M.
登録日2017-01-18
公開日2017-06-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.
EMBO J., 36, 2017
5CMF
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GTA mutant with mercury - E303A
分子名称: Histo-blood group ABO system transferase, MERCURY (II) ION
著者Gagnon, S.M.L, Blackler, R.J.
登録日2015-07-16
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Glycosyltransfer in mutants of putative catalytic residue Glu303 of the human ABO(H) A and B blood group glycosyltransferases GTA and GTB proceeds through a labile active site.
Glycobiology, 27, 2017
5N11
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BU of 5n11 by Molmil
Crystal structure of Human beta1-coronavirus OC43 NL/A/2005 Hemagglutinin-Esterase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ...
著者Bakkers, M.J.G, Feitsma, L.J, de Groot, R.J, Huizinga, E.G.
登録日2017-02-04
公開日2017-03-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Betacoronavirus Adaptation to Humans Involved Progressive Loss of Hemagglutinin-Esterase Lectin Activity.
Cell Host Microbe, 21, 2017
5C1Z
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BU of 5c1z by Molmil
Parkin (UblR0RBR)
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ...
著者kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H.
登録日2015-06-15
公開日2015-07-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
5NJN
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BU of 5njn by Molmil
Roll out the beta-barrel: structure and mechanism of Pac13, a unique nucleoside dehydratase
分子名称: Putative cupin_2 domain-containing isomerase
著者Michailidou, F, Bent, A.F, Naismith, J.H, Goss, R.J.M.
登録日2017-03-29
公開日2018-03-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Pac13 is a Small, Monomeric Dehydratase that Mediates the Formation of the 3'-Deoxy Nucleoside of Pacidamycins.
Angew. Chem. Int. Ed. Engl., 56, 2017
5COJ
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BU of 5coj by Molmil
Structure of Hydroxyethylthiazole kinase ThiM from Staphylococcus aureus in complex with native substrate 2-(4-methyl-1,3-thiazol-5-yl)ethanol.
分子名称: 2-(4-METHYL-THIAZOL-5-YL)-ETHANOL, Hydroxyethylthiazole kinase, MAGNESIUM ION
著者Drebes, J, Kuenz, M, Eberle, R.J, Oberthuer, D, Cang, H, Wrenger, C, Betzel, C.
登録日2015-07-20
公開日2016-03-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections.
Sci Rep, 6, 2016
5CM5
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Structure of Hydroxyethylthiazole Kinase ThiM from Staphylococcus aureus
分子名称: Hydroxyethylthiazole kinase
著者Drebes, J, Kuenz, M, Eberle, R.J, Oberthuer, D, Cang, H, Wrenger, C, Betzel, C.
登録日2015-07-16
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections.
Sci Rep, 6, 2016
8TOW
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Structure of a mutated photosystem II complex reveals perturbation of the oxygen-evolving complex
分子名称: (3R)-beta,beta-caroten-3-ol, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ...
著者Flesher, D.A, Liu, J, Wang, J, Gisriel, C.J, Yang, K.R, Batista, V.S, Debus, R.J, Brudvig, G.W.
登録日2023-08-04
公開日2024-06-19
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.14 Å)
主引用文献Mutation-induced shift of the photosystem II active site reveals insight into conserved water channels.
J.Biol.Chem., 300, 2024
5CMG
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GTA mutant with mercury- E303C
分子名称: Histo-blood group ABO system transferase, MERCURY (II) ION
著者Gagnon, S.M, Blackler, R.J.
登録日2015-07-16
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Glycosyltransfer in mutants of putative catalytic residue Glu303 of the human ABO(H) A and B blood group glycosyltransferases GTA and GTB proceeds through a labile active site.
Glycobiology, 27, 2017
5CMJ
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GTA mutant with mercury - E303Q
分子名称: Histo-blood group ABO system transferase, MERCURY (II) ION
著者Gagnon, S.M.L, Blackler, R.J.
登録日2015-07-16
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Glycosyltransfer in mutants of putative catalytic residue Glu303 of the human ABO(H) A and B blood group glycosyltransferases GTA and GTB proceeds through a labile active site.
Glycobiology, 27, 2017
5CMH
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GTA mutant with mercury - E303D
分子名称: Histo-blood group ABO system transferase, MERCURY (II) ION
著者Gagnon, S.M.L, Blackler, R.J.
登録日2015-07-16
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Glycosyltransfer in mutants of putative catalytic residue Glu303 of the human ABO(H) A and B blood group glycosyltransferases GTA and GTB proceeds through a labile active site.
Glycobiology, 27, 2017
8UF2
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BU of 8uf2 by Molmil
Apo SOS2 crystal structure in P1 space group
分子名称: SULFATE ION, Son of sevenless homolog 2
著者Gunn, R.J, Lawson, J.D.
登録日2023-10-03
公開日2024-01-10
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography.
J.Med.Chem., 67, 2024
8UH0
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SOS2 co-crystal structure with fragment bound (compound 10)
分子名称: 8-hydroxyquinoline-2-carbonitrile, Son of sevenless homolog 2
著者Gunn, R.J, Lawson, J.D.
登録日2023-10-06
公開日2024-01-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Discovery of Five SOS2 Fragment Hits with Binding Modes Determined by SOS2 X-Ray Cocrystallography.
J.Med.Chem., 67, 2024

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件を2024-08-07に公開中

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