3O5Z
| Crystal structure of the SH3 domain from p85beta subunit of phosphoinositide 3-kinase (PI3K) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Phosphatidylinositol 3-kinase regulatory subunit beta | Authors: | Chen, S, Xiao, Y, Ponnusamy, R, Tan, J, Lei, J, Hilgenfeld, R. | Deposit date: | 2010-07-28 | Release date: | 2011-08-10 | Last modified: | 2014-09-10 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | X-ray structure of the SH3 domain of the phosphoinositide 3-kinase p85 beta subunit Acta Crystallogr.,Sect.F, 67, 2011
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1NZE
| Crystal structure of PsbQ polypeptide of photosystem II from higher plants | Descriptor: | Oxygen-evolving enhancer protein 3, ZINC ION | Authors: | Calderone, V, Trabucco, M, Vujicic, A, Battistutta, R, Giacometti, G.M, Andreucci, F, Barbato, R, Zanotti, G. | Deposit date: | 2003-02-17 | Release date: | 2003-08-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of the PsbQ protein of photosystem II from higher plants Embo Rep., 4, 2003
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1U3G
| Structural and Functional Characterization of a 5,10-Methenyltetrahydrofolate Synthetase from Mycoplasma pneumoniae (GI: 13508087) | Descriptor: | 5,10-Methenyltetrahydrofolate Synthetase, 5-HYDROXYMETHYLENE-6-HYDROFOLIC ACID, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Chen, S, Yakunin, A.F, Proudfoot, M, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | Deposit date: | 2004-07-21 | Release date: | 2004-12-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of methenyltetrahydrofolate synthetase from Mycoplasma pneumoniae (GI: 13508087) at 2.2 A resolution Proteins, 56, 2004
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1D3W
| Crystal structure of ferredoxin 1 d15e mutant from azotobacter vinelandii at 1.7 angstrom resolution. | Descriptor: | FE3-S4 CLUSTER, FERREDOXIN 1, IRON/SULFUR CLUSTER | Authors: | Chen, K, Hirst, J, Camba, R, Bonagura, C.A, Stout, C.D, Burges, B.K, Armstrong, F.A. | Deposit date: | 1999-10-01 | Release date: | 1999-10-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Atomically defined mechanism for proton transfer to a buried redox centre in a protein. Nature, 405, 2000
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3NRH
| Crystal Structure of protein BF1032 from Bacteroides fragilis, Northeast Structural Genomics Consortium Target BfR309 | Descriptor: | uncharacterized protein BF1032 | Authors: | Seetharaman, J, Lew, S, Sahdev, S, Xiao, R, Ciccosanti, C, Wang, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-06-30 | Release date: | 2010-08-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Northeast Structural Genomics Consortium Target BfR309 To be Published, 2010
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3NRL
| Crystal Structure of protein RUMGNA_01417 from Ruminococcus gnavus, Northeast Structural Genomics Consortium Target UgR76 | Descriptor: | SULFATE ION, uncharacterized protein RUMGNA_01417 | Authors: | Seetharaman, J, Abashidze, M, Sahdev, S, Xiao, R, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-06-30 | Release date: | 2010-08-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Northeast Structural Genomics Consortium Target UgR76 To be Published
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1QRC
| TAILSPIKE PROTEIN, MUTANT W391A | Descriptor: | TAILSPIKE PROTEIN | Authors: | Schuler, B, Furst, F, Osterroth, F, Steinbacher, S, Huber, R, Seckler, R. | Deposit date: | 1999-06-13 | Release date: | 2000-04-12 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Plasticity and steric strain in a parallel beta-helix: rational mutations in the P22 tailspike protein. Proteins, 39, 2000
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4N04
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4CNI
| Crystal structure of the Fab portion of Olokizumab in complex with IL- 6 | Descriptor: | INTERLEUKIN-6, OLOKIZUMAB HEAVY CHAIN, FAB PORTION, ... | Authors: | Shaw, S, Bourne, T, Meier, C, Carrington, B, Gelinas, R, Henry, A, Popplewell, A, Adams, R, Baker, T, Rapecki, S, Marshall, D, Neale, H, Lawson, A. | Deposit date: | 2014-01-22 | Release date: | 2014-04-30 | Last modified: | 2019-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery and Characterization of Olokizumab: A Humanized Antibody Targeting Interleukin-6 and Neutralizing Gp130-Signaling. Mabs, 6, 2014
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3WPL
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3WNB
| Crystal structure of EF-Pyl in complex with GMPPNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein translation elongation factor 1A | Authors: | Yanagisawa, T, Ishii, R, Fukunaga, R, Sengoku, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2013-12-08 | Release date: | 2014-12-10 | Last modified: | 2020-05-06 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A SelB/EF-Tu/aIF2 gamma-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNA(Cys.). J. Struct. Funct. Genomics, 16, 2015
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5FXS
| IGFR-1R complex with a pyrimidine inhibitor. | Descriptor: | 2-[4-[4-[[(6Z)-5-chloranyl-6-pyrazolo[1,5-a]pyridin-3-ylidene-1H-pyrimidin-2-yl]amino]-3,5-dimethyl-pyrazol-1-yl]piperidin-1-yl]-N,N-dimethyl-ethanamide, ACETATE ION, INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR | Authors: | Degorce, S, Boyd, S, Curwen, J, Ducray, R, Halsall, C, Jones, C, Lach, F, Lenz, E, Pass, M, Pass, S, Trigwell, C, Norman, R, Phillips, C. | Deposit date: | 2016-03-02 | Release date: | 2016-10-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery of a Potent, Selective, Orally Bioavailable, and Efficacious Novel 2-(Pyrazol-4-ylamino)-pyrimidine Inhibitor of the Insulin-like Growth Factor-1 Receptor (IGF-1R). J. Med. Chem., 59, 2016
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1QA1
| TAILSPIKE PROTEIN, MUTANT V331G | Descriptor: | TAILSPIKE PROTEIN | Authors: | Baxa, U, Steinbacher, S, Weintraub, A, Huber, R, Seckler, R. | Deposit date: | 1999-04-10 | Release date: | 2000-01-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mutations improving the folding of phage P22 tailspike protein affect its receptor binding activity. J.Mol.Biol., 293, 1999
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3WS2
| N288Q-N321Q mutant BETA-LACTAMASE DERIVED FROM CHROMOHALOBACTER SP.560 (Condition-1C) | Descriptor: | Beta-lactamase, CALCIUM ION, CESIUM ION | Authors: | Arai, S, Yonezawa, Y, Okazaki, N, Matsumoto, F, Shimizu, R, Yamada, M, Adachi, M, Tamada, T, Tokunaga, H, Ishibashi, M, Tokunaga, M, Kuroki, R. | Deposit date: | 2014-02-27 | Release date: | 2015-03-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of a highly acidic beta-lactamase from the moderate halophile Chromohalobacter sp. 560 and the discovery of a Cs(+)-selective binding site Acta Crystallogr.,Sect.D, 71, 2015
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5FXR
| IGFR-1R complex with a pyrimidine inhibitor. | Descriptor: | 5-chloranyl-4-imidazo[1,2-a]pyridin-3-yl-N-(3-methyl-1-piperidin-4-yl-pyrazol-4-yl)pyrimidin-2-amine, INSULIN-LIKE GROWTH FACTOR 1 RECEPTOR | Authors: | Degorce, S, Boyd, S, Curwen, J, Ducray, R, Halsall, C, Jones, C, Lach, F, Lenz, E, Pass, M, Pass, S, Trigwell, C, Norman, R, Phillips, C. | Deposit date: | 2016-03-02 | Release date: | 2016-10-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Discovery of a Potent, Selective, Orally Bioavailable, and Efficacious Novel 2-(Pyrazol-4-ylamino)-pyrimidine Inhibitor of the Insulin-like Growth Factor-1 Receptor (IGF-1R). J. Med. Chem., 59, 2016
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3OEZ
| crystal structure of the L317I mutant of the chicken c-Src tyrosine kinase domain complexed with imatinib | Descriptor: | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, ACETATE ION, GLYCEROL, ... | Authors: | Boubeva, R, Pernot, L, Perozzo, R, Scapozza, L. | Deposit date: | 2010-08-13 | Release date: | 2011-08-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | a single amino-acid dictates the dynamics of the switch between active and inactive C-Src conformation To be Published
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5FZO
| Crystal structure of the catalytic domain of human JmjD1C | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, MANGANESE (II) ION, ... | Authors: | Nowak, R, Talon, R, Krojer, T, Goubin, S, McDonough, M, Fairhead, M, Oppermann, U, Johansson, C. | Deposit date: | 2016-03-15 | Release date: | 2016-03-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Crystal Structure of the Catalytic Domain of Human Jmjd1C To be Published
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3J1R
| Filaments from Ignicoccus hospitalis Show Diversity of Packing in Proteins Containing N-terminal Type IV Pilin Helices | Descriptor: | archaeal adhesion filament core | Authors: | Yu, X, Goforth, C, Meyer, C, Rachel, R, Wirth, R, Schroeder, G.F, Egelman, E.H. | Deposit date: | 2012-05-18 | Release date: | 2012-06-20 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (7.5 Å) | Cite: | Filaments from Ignicoccus hospitalis Show Diversity of Packing in Proteins Containing N-Terminal Type IV Pilin Helices. J.Mol.Biol., 422, 2012
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1CPC
| ISOLATION, CRYSTALLIZATION, CRYSTAL STRUCTURE ANALYSIS AND REFINEMENT OF CONSTITUTIVE C-PHYCOCYANIN FROM THE CHROMATICALLY ADAPTING CYANOBACTERIUM FREMYELLA DIPLOSIPHON AT 1.66 ANGSTROMS RESOLUTION | Descriptor: | C-PHYCOCYANIN (ALPHA SUBUNIT), C-PHYCOCYANIN (BETA SUBUNIT), PHYCOCYANOBILIN | Authors: | Duerring, M, Schmidt, G.B, Huber, R. | Deposit date: | 1990-10-11 | Release date: | 1993-01-15 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Isolation, crystallization, crystal structure analysis and refinement of constitutive C-phycocyanin from the chromatically adapting cyanobacterium Fremyella diplosiphon at 1.66 A resolution. J.Mol.Biol., 217, 1991
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3OC3
| Crystal structure of the Mot1 N-terminal domain in complex with TBP | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HELICASE MOT1, TRANSCRIPTION INITIATION FACTOR TFIID (TFIID-1) | Authors: | Wollmann, P, Cui, S, Viswanathan, R, Berninghausen, O, Wells, M.N, Moldt, M, Witte, G, Butryn, A, Wendler, P, Beckmann, R, Auble, D.T, Hopfner, K.-P. | Deposit date: | 2010-08-09 | Release date: | 2011-07-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP. Nature, 475, 2011
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4DFD
| Crystal structure of had family enzyme bt-2542 (target efi-501088) from bacteroides thetaiotaomicron, magnesium complex | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Putative haloacid dehalogenase-like hydrolase, ... | Authors: | Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Allen, K, Dunaway-Mariano, D, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2012-01-23 | Release date: | 2012-02-01 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Protein Bt-2542 from Bacteroides Thetaiotaomicron (Target Efi-501088) To be Published
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1DBN
| MAACKIA AMURENSIS LEUKOAGGLUTININ (LECTIN) WITH SIALYLLACTOSE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, MANGANESE (II) ION, ... | Authors: | Imberty, A, Gautier, C, Lescar, J, Loris, R. | Deposit date: | 1999-11-03 | Release date: | 2000-06-14 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | An unusual carbohydrate binding site revealed by the structures of two Maackia amurensis lectins complexed with sialic acid-containing oligosaccharides. J.Biol.Chem., 275, 2000
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3TH6
| Crystal structure of Triosephosphate isomerase from Rhipicephalus (Boophilus) microplus. | Descriptor: | Triosephosphate isomerase | Authors: | Arreola, R, Rodriguez-Romero, A, Moraes, J, Gomez-Puyou, A, Perez-Montfort, R, Logullo, C. | Deposit date: | 2011-08-18 | Release date: | 2011-08-31 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural and biochemical characterization of a recombinant triosephosphate isomerase from Rhipicephalus (Boophilus) microplus. Insect Biochem.Mol.Biol., 41, 2011
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3WND
| Crystal structure of EF-Pyl | Descriptor: | CITRIC ACID, Protein translation elongation factor 1A | Authors: | Yanagisawa, T, Ishii, R, Fukunaga, R, Sengoku, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2013-12-08 | Release date: | 2014-12-10 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | A SelB/EF-Tu/aIF2 gamma-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNA(Cys.). J. Struct. Funct. Genomics, 16, 2015
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1DJ2
| STRUCTURES OF ADENYLOSUCCINATE SYNTHETASE FROM TRITICUM AESTIVUM AND ARABIDOPSIS THALIANA | Descriptor: | ADENYLOSUCCINATE SYNTHETASE, GUANOSINE-5'-DIPHOSPHATE | Authors: | Prade, L, Cowan-Jacob, S.W, Chemla, P, Potter, S, Ward, E, Fonne-Pfister, R. | Deposit date: | 1999-12-01 | Release date: | 2000-03-24 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structures of adenylosuccinate synthetase from Triticum aestivum and Arabidopsis thaliana. J.Mol.Biol., 296, 2000
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