6C24
 
 | | Cryo-EM structure of PRC2 bound to cofactors AEBP2 and JARID2 in the Extended Active State | | Descriptor: | Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH2, JARID2-substrate, ... | | Authors: | Kasinath, V, Faini, M, Poepsel, S, Reif, D, Feng, A, Stjepanovic, G, Aebersold, R, Nogales, E. | | Deposit date: | 2018-01-06 | | Release date: | 2018-01-24 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structures of human PRC2 with its cofactors AEBP2 and JARID2.
Science, 359, 2018
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6C3P
 | | Cryo-EM structure of human KATP bound to ATP and ADP in propeller form | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ... | | Authors: | Lee, K.P.K, Chen, J, MacKinnon, R. | | Deposit date: | 2018-01-10 | | Release date: | 2018-01-24 | | Method: | ELECTRON MICROSCOPY (5.6 Å) | | Cite: | Molecular structure of human KATP in complex with ATP and ADP.
Elife, 6, 2017
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4N62
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2KLB
 | | NMR Solution structure of a diflavin flavoprotein A3 from Nostoc sp. PCC 7120, Northeast Structural Genomics Consortium Target NsR431C | | Descriptor: | Putative diflavin flavoprotein A 3 | | Authors: | Swapna, G.V.T, Ciccosanti, C, Wang, D, Jiang, M, Xiao, R, Acton, T.B, Everett, J.K, Nair, R, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-06-30 | | Release date: | 2009-07-21 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | NMR Solution structure of a diflavin flavoprotein A3 from Nostoc sp. PCC 7120, Northeast Structural Genomics Consortium Target NsR431C
To be Published
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2KKS
 | | Solution Structure Of Protein DSY2949 From Desulfitobacterium hafniense. Northeast Structural Genomics Consortium Target DhR27 | | Descriptor: | Uncharacterized protein | | Authors: | Wu, Y, Mills, J.L, Wang, H, Ciccosanti, C, Jiang, M, Sukumaran, D, Zhang, Q, Nair, R, Rost, B, Acton, T, Xiao, R, Swapna, G.V.T, Everett, J, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-06-29 | | Release date: | 2009-08-25 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Solution Structure Of Protein DSY2949 From Desulfitobacterium hafniense. Northeast Structural Genomics Consortium Target DhR27
To be Published
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2K5V
 | | SOLUTION NMR STRUCTURE OF the second OB-fold domain of replication protein A from Methanococcus maripaludis. NORTHEAST STRUCTURAL GENOMICS TARGET MrR110B. | | Descriptor: | Replication protein A | | Authors: | Aramini, J.M, Maglaqui, M, Jiang, M, Ciccosanti, C, Xiao, R, Nair, R, Everett, J.K, Swapna, G.VT, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-06-30 | | Release date: | 2008-08-19 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | SOLUTION NMR STRUCTURE OF the second OB-fold domain of replication protein A from Methanococcus maripaludis. NORTHEAST STRUCTURAL GENOMICS TARGET MrR110B.
To be Published
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6BXR
 | | Crystal structure of Toxoplasma gondii Mitochondrial Association Factor 1 B (MAF1B) | | Descriptor: | BROMIDE ION, GLYCEROL, Mitochondrial association factor 1, ... | | Authors: | Parker, M.L, Ramaswamy, R, Boulanger, M.J. | | Deposit date: | 2017-12-18 | | Release date: | 2018-12-19 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | A Toxoplasma gondii locus required for the direct manipulation of host mitochondria has maintained multiple ancestral functions.
Mol. Microbiol., 108, 2018
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6C9D
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6BXW
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2KC7
 | | Solution NMR structure of Bacteroides fragilis protein BF1650. Northeast Structural Genomics Consortium target BfR218 | | Descriptor: | bfr218_protein | | Authors: | Eletsky, A, Wu, Y, Sukumaran, D, Lee, H, Lee, D.Y, Jiang, M, Foote, E.L, Xiao, R, Nair, R, Everett, J.K, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Prestegard, J.H, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-12-17 | | Release date: | 2009-01-13 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of Bacteroides fragilis protein BF1650. Northeast Structural Genomics Consortium target BfR218
To be Published
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2KHN
 | | NMR solution structure of the EH 1 domain from human intersectin-1 protein. Northeast Structural Genomics Consortium target HR3646E. | | Descriptor: | Intersectin-1 | | Authors: | Mills, J.L, Ghosh, A, Garcia, E, Zhang, Q, Shastry, R, Foote, E.L, Janjua, H, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-04-09 | | Release date: | 2009-04-21 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure of the EH 1 domain from human intersectin-1 protein. Northeast Structural Genomics Consortium target HR3646E.
To be Published
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6C1I
 | | Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with T0070907 | | Descriptor: | 2-chloro-5-nitro-N-(pyridin-4-yl)benzamide, Peroxisome proliferator-activated receptor gamma, nonanoic acid | | Authors: | Shang, J, Fuhrmann, J, Brust, R, Kojetin, D.J. | | Deposit date: | 2018-01-04 | | Release date: | 2018-12-12 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.26 Å) | | Cite: | A structural mechanism for directing corepressor-selective inverse agonism of PPAR gamma.
Nat Commun, 9, 2018
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2KKL
 | | Solution NMR structure of FHA domain of Mb1858 from Mycobacterium bovis. Northeast Structural Genomics Consortium Target MbR243C (24-155). | | Descriptor: | Uncharacterized protein Mb1858 | | Authors: | Yang, Y, Ramelot, T.A, Wang, D, Foote, E.L, Jiang, M, Nair, R, Rost, B, Swapna, G, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-06-25 | | Release date: | 2009-07-07 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Solution NMR structure of FHA domain of Mb1858 from Mycobacterium bovis. Northeast Structural Genomics Consortium Target MbR243C (24-155).
To be Published
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4N63
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6BPM
 | | The crystal structure of the Ferric-Catecholate import receptor Fiu from K12 E. coli: Closed form (C21) | | Descriptor: | (20S)-2,5,8,11,14,17-HEXAMETHYL-3,6,9,12,15,18-HEXAOXAHENICOSANE-1,20-DIOL, Catecholate siderophore receptor Fiu, octyl beta-D-glucopyranoside | | Authors: | Grinter, R. | | Deposit date: | 2017-11-23 | | Release date: | 2018-11-28 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The structure of the bacterial iron-catecholate transporter Fiu suggests that it imports substrates via a two-step mechanism.
J.Biol.Chem., 2019
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2K4Y
 | | NMR Structure of FeoA-like protein from Clostridium acetobutylicum: Northeast Structural Genomics Consortium Target CaR178 | | Descriptor: | FeoA-like protein | | Authors: | Singarapu, K, Wu, Y, Hua, J, Sukumaran, D, Zhao, L, Jiang, M, Foote, E.L, Xiao, R, Nair, R, Baran, M.C, Swapna, G.V.T, Acton, T, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2008-06-20 | | Release date: | 2008-09-02 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | NMR Structure of FeoA-like protein from Clostridium acetobutylicum: Northeast Structural Genomics Consortium Target CaR178
To be Published
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2KL5
 | | Solution NMR Structure of protein yutD from B.subtilis, Northeast Structural Genomics Consortium Target SR232 | | Descriptor: | Uncharacterized protein yutD | | Authors: | Liu, G, Hamilton, K, Xiao, R, Ciccosanti, C, Ho, C.J, Everett, J, Nair, R, Acton, T, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-06-30 | | Release date: | 2009-07-14 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Solution NMR Structure of protein yutD from B.subtilis, Northeast Structural Genomics Consortium Target Target SR232
To be Published
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2KEY
 | | Solution NMR structure of a domain from a putative phage integrase protein BF2284 from Bacteroides fragilis, Northeast Structural Genomics Consortium Target BfR257C | | Descriptor: | Putative phage integrase | | Authors: | Mills, J.L, Sathyamoorthy, B, Sukumaran, D.K, Lee, D, Ciccosanti, C, Jiang, M, Xiao, R, Acton, T.B, Swapna, G.V.T, Rost, B, Nair, R, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-02-06 | | Release date: | 2009-04-14 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Solution NMR Structure of a Domain from a Putative Phage Integrase Protein, BF2284, from Bacteroides fragilis, Northeast Structural Genomics Consortium Target BfR257C
To be Published
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6BJ5
 | | Structure of the Clinically used Myxomaviral Serine Protease Inhibitor 1 (SERP-1) | | Descriptor: | 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Mahon, B.P, Lomelino, C.L, McKenna, R. | | Deposit date: | 2017-11-05 | | Release date: | 2018-11-07 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of the Clinically used Myxomaviral Serine Protease Inhibitor 1 (SERP-1)
To Be Published
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4N5K
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4C2C
 | | Crystal structure of the protease CtpB in an active state | | Descriptor: | CARBOXY-TERMINAL PROCESSING PROTEASE CTPB, PEPTIDE1, PEPTIDE2 | | Authors: | Mastny, M, Heuck, A, Kurzbauer, R, Clausen, T. | | Deposit date: | 2013-08-17 | | Release date: | 2013-12-04 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Ctpb Assembles a Gated Protease Tunnel Regulating Cell-Cell Signaling During Spore Formation in Bacillus Subtilis.
Cell(Cambridge,Mass.), 155, 2013
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2O73
 | | Structure of OHCU decarboxylase in complex with allantoin | | Descriptor: | 1-(2,5-DIOXO-2,5-DIHYDRO-1H-IMIDAZOL-4-YL)UREA, OHCU decarboxylase | | Authors: | Cendron, L, Berni, R, Folli, C, Ramazzina, I, Percudani, R, Zanotti, G. | | Deposit date: | 2006-12-10 | | Release date: | 2007-04-10 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation.
J.Biol.Chem., 282, 2007
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3BA0
 | | Crystal structure of full-length human MMP-12 | | Descriptor: | ACETOHYDROXAMIC ACID, CALCIUM ION, Macrophage metalloelastase, ... | | Authors: | Bertini, I, Calderone, V, Fragai, M, Jaiswal, R, Luchinat, C, Melikian, M, Myonas, E, Svergun, D.I. | | Deposit date: | 2007-11-07 | | Release date: | 2008-07-29 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Evidence of reciprocal reorientation of the catalytic and hemopexin-like domains of full-length MMP-12.
J.Am.Chem.Soc., 130, 2008
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2KGR
 | | Solution structure of protein ITSN1 from Homo sapiens. Northeast Structural Genomics Consortium target HR5524A | | Descriptor: | Intersectin-1 | | Authors: | Wu, Y, Ghosh, A, Shastry, R, Hua, J, Ciccosanti, C, Zhang, Q, Jiang, M, Swapna, G, Acton, T, Xiao, R, Everett, J, Montelione, G, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2009-03-16 | | Release date: | 2009-03-31 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of protein ITSN1 from Homo sapiens. Northeast Structural Genomics Consortium target HR5524A
To be Published
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6BGQ
 | | Caspase-3 Mutant - S150D | | Descriptor: | AZIDE ION, Ac-Asp-Glu-Val-Asp-CMK, CHLORIDE ION, ... | | Authors: | Thomas, M.E, Grinshpon, R, Swartz, P.D, Clark, A.C. | | Deposit date: | 2017-10-29 | | Release date: | 2018-02-21 | | Last modified: | 2018-04-25 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Modifications to a common phosphorylation network provide individualized control in caspases.
J. Biol. Chem., 293, 2018
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