5MZ5
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![BU of 5mz5 by Molmil](/molmil-images/mine/5mz5) | Crystal structure of aldehyde dehydrogenase 21 (ALDH21) from Physcomitrella patens in its apoform | 分子名称: | 1,2-ETHANEDIOL, ALDH21), DI(HYDROXYETHYL)ETHER, ... | 著者 | Kopecny, D, Koncitikova, R, Briozzo, P, Morera, S. | 登録日 | 2017-01-30 | 公開日 | 2017-08-09 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | The ALDH21 gene found in lower plants and some vascular plants codes for a NADP(+) -dependent succinic semialdehyde dehydrogenase. Plant J., 92, 2017
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7L6V
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7L8K
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![BU of 7l8k by Molmil](/molmil-images/mine/7l8k) | Crystal structure of human GPX4-U46C | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, PHOSPHATE ION, ... | 著者 | Forouhar, F, Liu, H, Seibt, T, Saneto, R, Wigby, K, Friedman, J, Xia, X, Shchepinov, M.S, Ramesh, S, Conrad, M, Stockwell, B.R. | 登録日 | 2020-12-31 | 公開日 | 2021-12-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Patient-derived variant of GPX4 reveals the structural basis for its catalytic activity and degradation mechanism Nat.Chem.Biol., 2021
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4R7G
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![BU of 4r7g by Molmil](/molmil-images/mine/4r7g) | Determination of the formylglycinamide ribonucleotide amidotransferase ammonia pathway by combining 3D-RISM theory with experiment | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Phosphoribosylformylglycinamidine synthase, ... | 著者 | Tanwar, A.S, Sindhikara, D.J, Hirata, F, Anand, R. | 登録日 | 2014-08-27 | 公開日 | 2015-01-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Determination of the formylglycinamide ribonucleotide amidotransferase ammonia pathway by combining 3D-RISM theory with experiment. Acs Chem.Biol., 10, 2015
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7L8Q
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![BU of 7l8q by Molmil](/molmil-images/mine/7l8q) | Crystal structure of human GPX4-U46C with oxidized Cys-46 | 分子名称: | ACETATE ION, Phospholipid hydroperoxide glutathione peroxidase | 著者 | Forouhar, F, Liu, H, Seibt, T, Saneto, R, Wigby, K, Friedman, J, Xia, X, Shchepinov, M.S, Ramesh, S, Conrad, M, Stockwell, B.R. | 登録日 | 2020-12-31 | 公開日 | 2021-12-29 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Patient-derived variant of GPX4 reveals the structural basis for its catalytic activity and degradation mechanism Nat.Chem.Biol., 2021
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7L8R
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![BU of 7l8r by Molmil](/molmil-images/mine/7l8r) | Crystal structure of human GPX4-U46C mutant K48A | 分子名称: | Isoform Cytoplasmic of Phospholipid hydroperoxide glutathione peroxidase, THIOCYANATE ION | 著者 | Forouhar, F, Liu, H, Seibt, T, Saneto, R, Wigby, K, Friedman, J, Xia, X, Shchepinov, M.S, Ramesh, S, Conrad, M, Stockwell, B.R. | 登録日 | 2020-12-31 | 公開日 | 2021-12-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Patient-derived variant of GPX4 reveals the structural basis for its catalytic activity and degradation mechanism Nat.Chem.Biol., 2021
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7L8L
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![BU of 7l8l by Molmil](/molmil-images/mine/7l8l) | Crystal structure of human R152H GPX4-U46C | 分子名称: | Phospholipid hydroperoxide glutathione peroxidase, THIOCYANATE ION | 著者 | Forouhar, F, Liu, H, Seibt, T, Saneto, R, Wigby, K, Friedman, J, Xia, X, Shchepinov, M.S, Ramesh, S, Conrad, M, Stockwell, B.R. | 登録日 | 2020-12-31 | 公開日 | 2021-12-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Patient-derived variant of GPX4 reveals the structural basis for its catalytic activity and degradation mechanism Nat.Chem.Biol., 2021
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7L8M
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![BU of 7l8m by Molmil](/molmil-images/mine/7l8m) | Crystal structure of human GPX4-U46C mutant K48L | 分子名称: | Phospholipid hydroperoxide glutathione peroxidase | 著者 | Forouhar, F, Liu, H, Seibt, T, Saneto, R, Friedman, J, Xia, X, Shchepinov, M.S, Ramesh, S, Conrad, M, Stockwell, B.R. | 登録日 | 2020-12-31 | 公開日 | 2021-12-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Patient-derived variant of GPX4 reveals the structural basis for its catalytic activity and degradation mechanism Nat.Chem.Biol., 2021
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5CCS
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![BU of 5ccs by Molmil](/molmil-images/mine/5ccs) | Human Cyclophilin D Complexed with Inhibitor | 分子名称: | 1-(4-aminobenzyl)-3-{2-oxo-2-[(2R)-2-phenylpyrrolidin-1-yl]ethyl}urea, Peptidyl-prolyl cis-trans isomerase F, mitochondrial | 著者 | Gibson, R.P, Shore, E, Kershaw, N, Awais, M, Javed, A, Latawiec, D, Pandalaneni, S, Wen, L, Berry, N, O'Neill, P, Sutton, R, Lian, L.Y. | 登録日 | 2015-07-02 | 公開日 | 2016-07-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Human Cyclophilin D Complexed with Inhibitor To Be Published
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7KQX
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![BU of 7kqx by Molmil](/molmil-images/mine/7kqx) | MIF Y99C homotrimeric mutant | 分子名称: | GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ... | 著者 | Manjula, R, Georgios, P, Lolis, E.J. | 登録日 | 2020-11-18 | 公開日 | 2022-01-19 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A Cysteine Variant at an Allosteric Site Alters MIF Dynamics and Biological Function in Homo- and Heterotrimeric Assemblies. Front Mol Biosci, 9, 2022
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5CDE
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![BU of 5cde by Molmil](/molmil-images/mine/5cde) | R372A mutant of Xaa-Pro dipeptidase from Xanthomonas campestris | 分子名称: | Proline dipeptidase, SULFATE ION, ZINC ION | 著者 | Kumar, A, Are, V, Ghosh, B, Jamdar, S, Makde, R. | 登録日 | 2015-07-03 | 公開日 | 2016-09-14 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | R372A mutant of Xaa-Pro dipeptidase from Xanthomonas campestris at 1.85 Angstrom resolution To Be Published
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5NHG
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![BU of 5nhg by Molmil](/molmil-images/mine/5nhg) | Crystal structure of the human dihydrolipoamide dehydrogenase | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dihydrolipoyl dehydrogenase, ... | 著者 | Szabo, E, Mizsei, R, Wilk, P, Zambo, Z, Torocsik, B, Weiss, M.S, Adam-Vizi, V, Ambrus, A. | 登録日 | 2017-03-21 | 公開日 | 2018-05-16 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Crystal structures of the disease-causing D444V mutant and the relevant wild type human dihydrolipoamide dehydrogenase. Free Radic. Biol. Med., 124, 2018
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7KSQ
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![BU of 7ksq by Molmil](/molmil-images/mine/7ksq) | The Structure of the moss PSI-LHCI reveals the evolution of the LHCI antenna | 分子名称: | (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | 著者 | Riddle, R, Gorski, C, Toporik, H, Dobson, Z, Da, Z, Williams, D, Mazor, Y. | 登録日 | 2020-11-23 | 公開日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | The structure of the Physcomitrium patens photosystem I reveals a unique Lhca2 paralogue replacing Lhca4. Nat.Plants, 8, 2022
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7KUX
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![BU of 7kux by Molmil](/molmil-images/mine/7kux) | The Structure of the moss PSI-LHCI reveals the evolution of the LHCI antenna | 分子名称: | (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | 著者 | Riddle, R, Gorski, C, Toporik, H, Dobson, Z, Da, Z, Williams, D, Mazor, Y. | 登録日 | 2020-11-25 | 公開日 | 2022-03-30 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | The structure of the Physcomitrium patens photosystem I reveals a unique Lhca2 paralogue replacing Lhca4. Nat.Plants, 8, 2022
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7KU5
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![BU of 7ku5 by Molmil](/molmil-images/mine/7ku5) | The Structure of the moss PSI-LHCI reveals the evolution of the LHCI antenna | 分子名称: | BETA-CAROTENE, CHLOROPHYLL A, PsaO | 著者 | Riddle, R, Gorski, C, Toporik, H, Dobson, Z, Da, Z, Williams, D, Mazor, Y. | 登録日 | 2020-11-24 | 公開日 | 2022-03-30 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.76 Å) | 主引用文献 | The structure of the Physcomitrium patens photosystem I reveals a unique Lhca2 paralogue replacing Lhca4. Nat.Plants, 8, 2022
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5CKE
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![BU of 5cke by Molmil](/molmil-images/mine/5cke) | E.coli MazF E24A form IIa | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, Endoribonuclease MazF, SULFATE ION | 著者 | Zorzini, V, Loris, R. | 登録日 | 2015-07-15 | 公開日 | 2016-04-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.311 Å) | 主引用文献 | Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF. J.Biol.Chem., 291, 2016
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5NM9
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![BU of 5nm9 by Molmil](/molmil-images/mine/5nm9) | Crystal structure of the placozoa Trichoplax adhaerens Smad4-MH1 bound to the GGCGC site. | 分子名称: | DNA (5'-D(P*AP*TP*GP*CP*GP*GP*GP*CP*GP*CP*GP*CP*CP*CP*GP*CP*AP*T)-3'), Mothers against decapentaplegic homolog, ZINC ION | 著者 | Kaczmarska, Z, Freier, R, Marquez, J.A, Macias, M.J. | 登録日 | 2017-04-05 | 公開日 | 2017-11-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors. Nat Commun, 8, 2017
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5C6U
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![BU of 5c6u by Molmil](/molmil-images/mine/5c6u) | Rv3722c aminotransferase from Mycobacterium tuberculosis | 分子名称: | Aminotransferase, CHLORIDE ION, PHOSPHATE ION, ... | 著者 | OSIPIUK, J, Hatzos-Skintges, C, Jedrzejczak, R, Babnigg, G, Sacchettini, J, JOACHIMIAK, A, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) | 登録日 | 2015-06-23 | 公開日 | 2015-07-15 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Rv3722c aminotransferase from Mycobacterium tuberculosis. to be published
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4QUP
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![BU of 4qup by Molmil](/molmil-images/mine/4qup) | Crystal structure of stachydrine demethylase with N-methyl proline from low X-ray dose composite datasets | 分子名称: | 1-methyl-L-proline, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COBALT HEXAMMINE(III), ... | 著者 | Agarwal, R, Andi, B, Gizzi, A, Bonanno, J.B, Almo, S.C, Orville, A.M. | 登録日 | 2014-07-11 | 公開日 | 2015-07-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Tracking photoelectron induced in-crystallo enzyme catalysis To be Published
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5NN8
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![BU of 5nn8 by Molmil](/molmil-images/mine/5nn8) | Crystal structure of human lysosomal acid-alpha-glucosidase, GAA, in complex with acarbose | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Roig-Zamboni, V, Cobucci-Ponzano, B, Iacono, R, Ferrara, M.C, Germany, S, Parenti, G, Bourne, Y, Moracci, M. | 登録日 | 2017-04-08 | 公開日 | 2017-10-25 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structure of human lysosomal acid alpha-glucosidase-a guide for the treatment of Pompe disease. Nat Commun, 8, 2017
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5CMZ
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![BU of 5cmz by Molmil](/molmil-images/mine/5cmz) | Artificial HIV fusion inhibitor AP3 fused to the C-terminus of gp41 NHR | 分子名称: | 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Artificial HIV entry inhibitor AP3, ... | 著者 | Zhu, Y, Ye, S, Zhang, R. | 登録日 | 2015-07-17 | 公開日 | 2015-09-16 | 実験手法 | X-RAY DIFFRACTION (2.574 Å) | 主引用文献 | Improved Pharmacological and Structural Properties of HIV Fusion Inhibitor AP3 over Enfuvirtide: Highlighting Advantages of Artificial Peptide Strategy. Sci Rep, 5, 2015
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5NDY
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4R0R
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![BU of 4r0r by Molmil](/molmil-images/mine/4r0r) | Ebolavirus GP Prehairpin Intermediate Mimic | 分子名称: | eboIZN21 | 著者 | Clinton, T.R, Weinstock, M.T, Jacobsen, M.T, Szabo-Fresnais, N, Pandya, M.J, Whitby, F.G, Herbert, A.S, Prugar, L.I, McKinnon, R, Hill, C.P, Welch, B.D, Dye, J.M, Eckert, D.M, Kay, M.S. | 登録日 | 2014-08-01 | 公開日 | 2014-10-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Design and characterization of ebolavirus GP prehairpin intermediate mimics as drug targets. Protein Sci., 24, 2015
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7KWI
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7KW9
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![BU of 7kw9 by Molmil](/molmil-images/mine/7kw9) | NMR Structure of a tRNA 2'-phosphotransferase from Runella slithyformis in complex with NAD+ | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, tRNA 2'-phosphotransferase | 著者 | Alphonse, S, Dantuluri, S, Banerjee, A, Shuman, S, Ghose, R. | 登録日 | 2020-11-30 | 公開日 | 2021-10-13 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR solution structures of Runella slithyformis RNA 2'-phosphotransferase Tpt1 provide insights into NAD+ binding and specificity. Nucleic Acids Res., 49, 2021
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