5XPV
 
 | | Structure of the V domain of amphioxus IgVJ-C2 | | 分子名称: | amphioxus IgVJ-C2 | | 著者 | Chen, R, Qi, J, Zhang, N, Zhang, L, Yao, S, Wu, Y, Jiang, B, Wang, Z, Yuan, H, Zhang, Q, Xia, C. | | 登録日 | 2017-06-05 | | 公開日 | 2018-04-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Discovery and Analysis of Invertebrate IgVJ-C2 Structure from Amphioxus Provides Insight into the Evolution of the Ig Superfamily.
J. Immunol., 200, 2018
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1I96
 | | CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH THE TRANSLATION INITIATION FACTOR IF3 (C-TERMINAL DOMAIN) | | 分子名称: | 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | | 著者 | Pioletti, M, Schluenzen, F, Harms, J, Zarivach, R, Gluehmann, M, Avila, H, Bartels, H, Jacobi, C, Hartsch, T, Yonath, A, Franceschi, F. | | 登録日 | 2001-03-18 | | 公開日 | 2001-04-12 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | | 主引用文献 | Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.
EMBO J., 20, 2001
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8B4L
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5ZIH
 | | Crystal structure of the red light-activated channelrhodopsin Chrimson. | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Sensory opsin A,Chrimson | | 著者 | Oda, K, Vierock, J, Oishi, S, Taniguchi, R, Yamashita, K, Nishizawa, T, Hegemann, P, Nureki, O. | | 登録日 | 2018-03-15 | | 公開日 | 2018-11-21 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of the red light-activated channelrhodopsin Chrimson.
Nat Commun, 9, 2018
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8B4M
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4CA4
 | | Crystal structure of FimH lectin domain with the Tyr48Ala mutation, in complex with heptyl alpha-D-mannopyrannoside | | 分子名称: | FIMH, heptyl alpha-D-mannopyranoside | | 著者 | Rabbani, S, Bouckaert, J, Zalewski, A, Preston, R, Eid, S, Thompson, A, Puorger, C, Glockshuber, R, Ernst, B. | | 登録日 | 2013-10-06 | | 公開日 | 2014-10-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Mutation of Tyr137 of the universal Escherichia coli fimbrial adhesin FimH relaxes the tyrosine gate prior to mannose binding.
IUCrJ, 4, 2017
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5YU6
 | | CRYSTAL STRUCTURE OF EXPORTIN-5:RANGTP COMPLEX | | 分子名称: | 13-mer peptide, Exportin-5, GTP-binding nuclear protein Ran, ... | | 著者 | Yamazawa, R, Jiko, C, Lee, S.J, Yamashita, E. | | 登録日 | 2017-11-20 | | 公開日 | 2018-08-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.997 Å) | | 主引用文献 | Structural Basis for Selective Binding of Export Cargoes by Exportin-5
Structure, 26, 2018
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5U78
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5ZKB
 | | Crystal structure of rationally thermostabilized M2 muscarinic acetylcholine receptor bound with AF-DX 384 | | 分子名称: | Muscarinic acetylcholine receptor M2,Apo-cytochrome b562,Muscarinic acetylcholine receptor M2, N-[2-[(2S)-2-[(dipropylamino)methyl]piperidin-1-yl]ethyl]-6-oxidanylidene-5H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide | | 著者 | Suno, R, Maeda, S, Yasuda, S, Yamashita, K, Hirata, K, Horita, S, Tawaramoto, M.S, Tsujimoto, H, Murata, T, Kinoshita, M, Yamamoto, M, Kobilka, B.K, Iwata, S, Kobayashi, T. | | 登録日 | 2018-03-23 | | 公開日 | 2018-11-21 | | 最終更新日 | 2022-03-23 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structural insights into the subtype-selective antagonist binding to the M2muscarinic receptor
Nat. Chem. Biol., 14, 2018
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1PCA
 | | THREE DIMENSIONAL STRUCTURE OF PORCINE PANCREATIC PROCARBOXYPEPTIDASE A. A COMPARISON OF THE A AND B ZYMOGENS AND THEIR DETERMINANTS FOR INHIBITION AND ACTIVATION | | 分子名称: | CITRIC ACID, PROCARBOXYPEPTIDASE A PCPA, VALINE, ... | | 著者 | Guasch, A, Coll, M, Aviles, F.X, Huber, R. | | 登録日 | 1991-10-28 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Three-dimensional structure of porcine pancreatic procarboxypeptidase A. A comparison of the A and B zymogens and their determinants for inhibition and activation.
J.Mol.Biol., 224, 1992
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8BFG
 | | Solution structure of human apo/Calmodulin G113R (G114R) | | 分子名称: | Calmodulin-1 | | 著者 | Wimmer, R, Holler, C.V, Petersson, N.M, Brohus, M.B, Niemelae, M, Overgaard, M.T, Iwai, H. | | 登録日 | 2022-10-25 | | 公開日 | 2023-10-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Allosteric changes in protein stability and dynamics as pathogenic mechanism for calmodulin variants not affecting Ca 2+ coordinating residues.
Cell Calcium, 117, 2023
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1I95
 | | CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH EDEINE | | 分子名称: | 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | | 著者 | Pioletti, M, Schluenzen, F, Harms, J, Zarivach, R, Gluehmann, M, Avila, H, Bartels, H, Jacobi, C, Hartsch, T, Yonath, A, Franceschi, F. | | 登録日 | 2001-03-18 | | 公開日 | 2001-04-12 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | | 主引用文献 | Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.
EMBO J., 20, 2001
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8BWF
 | | PTBP1 RRM1 bound to an allosteric inhibitor | | 分子名称: | AMINO GROUP, GLYCEROL, Ligand, ... | | 著者 | Schmeing, S, Vetter, I, t Hart, P, Gasper, R. | | 登録日 | 2022-12-06 | | 公開日 | 2023-10-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Rationally designed stapled peptides allosterically inhibit PTBP1-RNA-binding.
Chem Sci, 14, 2023
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5YYM
 | | Crystal structures of E.coli arginyl-trna synthetase (argrs) in complex with substrate Arg | | 分子名称: | ARGININE, Arginine--tRNA ligase | | 著者 | Zhou, M, Ye, S, Stephen, P, Zhang, R.G, Wang, E.D, Giege, R, Lin, S.X. | | 登録日 | 2017-12-10 | | 公開日 | 2018-12-12 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structures Of E.Coli Arginyl-Trna Synthetase (Argrs) In Complex With Substrates
To Be Published
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1O9W
 | | F17-aG lectin domain from Escherichia coli in complex with N-acetyl-glucosamine | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F17A-G FIMBRIAL ADHESIN | | 著者 | Buts, L, De Genst, E, Loris, R, Oscarson, S, Lahmann, M, Messens, J, Brosens, E, Wyns, L, Bouckaert, J, De Greve, H. | | 登録日 | 2002-12-20 | | 公開日 | 2003-05-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The Fimbrial Adhesin F17-G of Enterotoxigenic Escherichia Coli Has an Immunoglobulin-Like Lectin Domain that Binds N-Acetylglucosamine
Mol.Microbiol., 49, 2003
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1LHS
 | | LOGGERHEAD SEA TURTLE MYOGLOBIN (AQUO-MET) | | 分子名称: | MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Nardini, M, Tarricone, C, Lania, A, Desideri, A, De Sanctis, G, Coletta, M, Petruzzelli, R, Ascenzi, P, Coda, A, Bolognesi, M. | | 登録日 | 1995-02-01 | | 公開日 | 1995-06-03 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Reptile heme protein structure: X-ray crystallographic study of the aquo-met and cyano-met derivatives of the loggerhead sea turtle (Caretta caretta) myoglobin at 2.0 A resolution.
J.Mol.Biol., 247, 1995
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5ZFU
 | | Structure of the ExbB/ExbD hexameric complex (ExbB6ExbD3TM) | | 分子名称: | 22-mer peptide from Biopolymer transport protein ExbD, Biopolymer transport protein ExbB | | 著者 | Yonekura, K, Yamashita, Y, Matsuoka, R, Maki-Yonekura, S. | | 登録日 | 2018-03-07 | | 公開日 | 2018-05-09 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | | 主引用文献 | Hexameric and pentameric complexes of the ExbBD energizer in the Ton system.
Elife, 7, 2018
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8BCU
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3GBE
 | | Crystal structure of the isomaltulose synthase SmuA from Protaminobacter rubrum in complex with the inhibitor deoxynojirimycin | | 分子名称: | 1,2-ETHANEDIOL, 1-DEOXYNOJIRIMYCIN, CITRATE ANION, ... | | 著者 | Ravaud, S, Robert, X, Haser, R, Aghajari, N. | | 登録日 | 2009-02-19 | | 公開日 | 2009-05-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural determinants of product specificity of sucrose isomerases
Febs Lett., 583, 2009
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5UBZ
 | | Fab structure of HIV gp120 specific mAb 1E12 | | 分子名称: | Anti-HIV1 gp120 mAb 1E12 Fab heavy chain, Anti-HIV1 gp120 mAb 1E12 Fab light chain | | 著者 | Pan, R, Kong, X.-P. | | 登録日 | 2016-12-21 | | 公開日 | 2018-01-10 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | High Antibody Diversity and Low Inter-clonal Competition Favor Production of Functional Neutralizing Antibodies
To be published
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5UC4
 | | Hsp90b N-terminal domain with inhibitors | | 分子名称: | 5-Hydroxy-4-(isoindoline-2-carbonyl)-2-isopropylbenzaldehyde, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Deng, J, Peng, S, Balch, M, Matts, R. | | 登録日 | 2016-12-21 | | 公開日 | 2018-01-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure-guided design of an Hsp90 beta N-terminal isoform-selective inhibitor.
Nat Commun, 9, 2018
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8BF0
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5URM
 | | Crystal structure of human BRR2 in complex with T-1206548 | | 分子名称: | 3-(5-{[(2R)-5-amino-2-cyclohexyl-7-oxo-2,3-dihydro-7H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-6-yl]methyl}furan-2-yl)benzoic acid, U5 small nuclear ribonucleoprotein 200 kDa helicase | | 著者 | Klein, M.G, Tjhen, R, Qin, L. | | 登録日 | 2017-02-11 | | 公開日 | 2017-07-19 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2.
J. Med. Chem., 60, 2017
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5UTX
 | | Crystal structure of thioredoxin-disulfide reductase from Vibrio vulnificus CMCP6 - apo form | | 分子名称: | PHOSPHATE ION, Thioredoxin reductase | | 著者 | Chang, C, Grimshaw, S, Maltseva, N, Mulligan, R, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2017-02-15 | | 公開日 | 2017-02-22 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | Crystal structure of thioredoxin-disulfide reductase from Vibrio vulnificus CMCP6 - apo form
To Be Published
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8BTY
 | | Structure of the active form of ScpB, the C5a-peptidase from Streptococcus agalactiae. | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, C5a peptidase, CALCIUM ION, ... | | 著者 | Kagawa, T.F, Cooney, J.C, Miclot, T, Cullen, R. | | 登録日 | 2022-11-30 | | 公開日 | 2023-11-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The 1.7 angstrom crystal structure of the C5a peptidase from Streptococcus agalactiae (ScpB) reveals an active site competent for catalysis.
Proteins, 92, 2024
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