5U78

Crystal structure of ORP8 PH domain in P1211 space group

Summary for 5U78

• Entry DOI: 10.2210/pdb5u78/pdb
• Related: 5U77
• Descriptor: Oxysterol-binding protein-related protein 8 (2 entities in total)
• Functional Keywords: oxsyterol, lipid transport, membrane contact site, phosphoinositide.
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 54439.90

Authors

Ghai, R.,Yang, H. (deposition date: 2016-12-12, release date: 2017-10-18, Last modification date: 2023-10-04)

• Primary citation: Ghai, R.,Du, X.,Wang, H.,Dong, J.,Ferguson, C.,Brown, A.J.,Parton, R.G.,Wu, J.W.,Yang, H.; ORP5 and ORP8 bind phosphatidylinositol-4, 5-biphosphate (PtdIns(4,5)P 2) and regulate its level at the plasma membrane.; Nat Commun, 8:757-757, 2017; PubMed: 28970484; DOI: 10.1038/s41467-017-00861-5

Experimental method

X-RAY DIFFRACTION (1.978 Å)