5TAZ
| Structure of rabbit RyR1 (ryanodine dataset, class 3) | 分子名称: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ... | 著者 | Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J. | 登録日 | 2016-09-10 | 公開日 | 2016-10-12 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural Basis for Gating and Activation of RyR1. Cell, 167, 2016
|
|
5TCL
| Thaumatin from 4.96 A wavelength data collection | 分子名称: | GLYCEROL, L(+)-TARTARIC ACID, Thaumatin-1 | 著者 | Aurelius, O, Duman, R, El Omari, K, Mykhaylyk, V, Wagner, A. | 登録日 | 2016-09-15 | 公開日 | 2017-09-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.201 Å) | 主引用文献 | Long-wavelength macromolecular crystallography - First successful native SAD experiment close to the sulfur edge. Nucl Instrum Methods Phys Res B, 411, 2017
|
|
8AIV
| Mpro of SARS COV-2 in complex with the MG-100 inhibitor | 分子名称: | 3C-like proteinase nsp5, CHLORIDE ION, tert-butyl N-[1-[(2S)-3-cyclopropyl-1-[[(2S,3R)-4-(methylamino)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepyrrolidin-3-yl]butan-2-yl]amino]-1-oxidanylidene-propan-2-yl]-2-oxidanylidene-pyridin-3-yl]carbamate | 著者 | El Kilani, H, Hilgenfeld, R. | 登録日 | 2022-07-27 | 公開日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Main Protease SARS-COV-2 in complex with the inhibitor MG-100 To Be Published
|
|
5T4Q
| Autoinhibited E. coli ATP synthase state 3 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | 著者 | Sobti, M, Smits, C, Wong, A.S.W, Ishmukhametov, R, Stock, D, Sandin, S, Stewart, A.G. | 登録日 | 2016-08-29 | 公開日 | 2017-01-04 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (8.53 Å) | 主引用文献 | Cryo-EM structures of the autoinhibitedE. coliATP synthase in three rotational states. Elife, 5, 2016
|
|
1I1W
| 0.89A Ultra high resolution structure of a Thermostable Xylanase from Thermoascus Aurantiacus | 分子名称: | ACETONE, ENDO-1,4-BETA-XYLANASE, ETHANOL, ... | 著者 | Natesh, R, Ramakumar, S, Viswamitra, M.A. | 登録日 | 2001-02-04 | 公開日 | 2003-01-07 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (0.89 Å) | 主引用文献 | Thermostable xylanase from Thermoascus aurantiacus at ultrahigh resolution (0.89 A) at 100 K and atomic resolution (1.11 A) at 293 K refined anisotropically to small-molecule accuracy. Acta Crystallogr.,Sect.D, 59, 2003
|
|
8AIU
| Mpro of SARS COV-2 in complex with the MG-97 inhibitor | 分子名称: | 3C-like proteinase nsp5, CHLORIDE ION, tert-butyl N-[1-[(2S)-3-cyclopropyl-1-[[(2S,3R)-4-(cyclopropylamino)-3-oxidanyl-4-oxidanylidene-1-[(3S)-2-oxidanylidenepyrrolidin-3-yl]butan-2-yl]amino]-1-oxidanylidene-propan-2-yl]-2-oxidanylidene-pyridin-3-yl]carbamate | 著者 | El Kilani, H, Hilgenfeld, R. | 登録日 | 2022-07-27 | 公開日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Main Protease SARS-COV-2 in complex with the inhibitor MG-97 To Be Published
|
|
5TAL
| Structure of rabbit RyR1 (Caffeine/ATP/Ca2+ dataset, class 1&2) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ... | 著者 | Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J. | 登録日 | 2016-09-10 | 公開日 | 2016-10-12 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural Basis for Gating and Activation of RyR1. Cell, 167, 2016
|
|
5TBA
| |
8AM5
| RCII/PSI complex, class 3 | 分子名称: | (1R,2S)-4-{(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4S)-4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaen-1-yl}-2,5,5-trimethylcyclohex-3-en-1-ol, (3'R)-3'-hydroxy-beta,beta-caroten-4-one, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... | 著者 | Zhao, Z, Vercellino, I, Knoppova, J, Sobotka, R, Murray, J.W, Nixon, P.J, Sazanov, L.A, Komenda, J. | 登録日 | 2022-08-02 | 公開日 | 2023-08-16 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The Ycf48 accessory factor occupies the site of the oxygen-evolving manganese cluster during photosystem II biogenesis. Nat Commun, 14, 2023
|
|
5YUL
| |
8AII
| High Resolution Crystal Structure of Enterococcus faecium Nicotinate Nucleotide Adenylyltransferase Complexed with Adenine | 分子名称: | ADENINE, MAGNESIUM ION, Probable nicotinate-nucleotide adenylyltransferase, ... | 著者 | Pandian, R, Jeje, O.A, Sayed, Y, Achilonu, I.A. | 登録日 | 2022-07-26 | 公開日 | 2023-08-16 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Obtaining high yield recombinant Enterococcus faecium nicotinate nucleotide adenylyltransferase for X-ray crystallography and biophysical studies. Int.J.Biol.Macromol., 250, 2023
|
|
8ATN
| Discovery of IRAK4 Inhibitor 38 | 分子名称: | Interleukin-1 receptor-associated kinase 4, ~{N}-[3-methyl-2-(3-methyl-3-oxidanyl-butyl)-6-(2-oxidanylpropan-2-yl)benzimidazol-5-yl]-6-(trifluoromethyl)pyridine-2-carboxamide | 著者 | Schafer, M, Bothe, U, Schmidt, N, Gunther, J, Nubbemeyer, R, Siebeneicher, H, Ring, S, Boemer, U, Peters, M, Denner, K, Himmel, H, Sutter, A, Terebesi, I, Lange, M, Wenger, A.M, Guimond, N, Thaler, T, Platzek, J, Eberspaecher, U, Steuber, H, Steinmeyer, A, Zollner, T.M. | 登録日 | 2022-08-23 | 公開日 | 2023-09-06 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.171 Å) | 主引用文献 | Discovery of IRAK4 Inhibitors BAY1834845 (Zabedosertib) and BAY1830839 . J.Med.Chem., 67, 2024
|
|
8AJ0
| Mpro of SARS COV-2 in complex with the RK-90 inhibitor | 分子名称: | (2R,3S)-3-[[(2S)-3-cyclopropyl-2-[2-oxidanylidene-3-(3-phenylpropanoylamino)pyridin-1-yl]propanoyl]amino]-N-methyl-2-oxidanyl-4-[(3S)-2-oxidanylidenepyrrolidin-3-yl]butanamide, 3C-like proteinase nsp5, CHLORIDE ION, ... | 著者 | El Kilani, H, Hilgenfeld, R. | 登録日 | 2022-07-27 | 公開日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.519 Å) | 主引用文献 | Main Protease SARS-COV-2 in complex with the inhibitor RK-90 To Be Published
|
|
8AGY
| |
8AIZ
| Mpro of SARS-CoV-2 in complex with the RK-68 inhibitor | 分子名称: | (2~{R},3~{S})-3-[[(2~{S})-3-cyclopropyl-2-[2-oxidanylidene-3-(2-phenylethanoylamino)pyridin-1-yl]propanoyl]amino]-~{N}-methyl-2-oxidanyl-4-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]butanamide, CHLORIDE ION, Replicase polyprotein 1ab | 著者 | El Kilani, H, Hilgenfeld, R. | 登録日 | 2022-07-27 | 公開日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.992 Å) | 主引用文献 | Main Protease SARS-CoV-2 in complex with the inhibitor RK-68 To Be Published
|
|
1ICY
| [ALA31,PRO32]-PNPY BOUND TO DPC MICELLES | 分子名称: | NEUROPEPTIDE Y | 著者 | Bader, R, Rytz, G, Lerch, M, Beck-Sickinger, A.G, Zerbe, O. | 登録日 | 2001-04-02 | 公開日 | 2002-05-08 | 最終更新日 | 2021-10-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Key motif to gain selectivity at the neuropeptide Y5-receptor: structure and dynamics of micelle-bound [Ala31, Pro32]-NPY. Biochemistry, 41, 2002
|
|
5TBW
| Crystal structure of chlorolissoclimide bound to the yeast 80S ribosome | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Konst, Z.A, Szklarski, A.R, Pellegrino, S, Michalak, S.E, Meyer, M, Zanette, C, Cencic, R, Nam, S, Horne, D.A, Pelletier, J, Mobley, D.L, Yusupova, G, Yusupov, M, Vanderwal, C.D. | 登録日 | 2016-09-13 | 公開日 | 2017-07-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Synthesis facilitates an understanding of the structural basis for translation inhibition by the lissoclimides. Nat Chem, 9, 2017
|
|
5T6J
| Structure of the MIND Complex Shows a Regulatory Focus of Yeast Kinetochore Assembly | 分子名称: | Kinetochore protein SPC24, Kinetochore protein SPC25, Kinetochore-associated protein DSN1 | 著者 | Valverde, R, Jenni, S, Dimitrova, Y, Khin, Y, Harrison, S.C. | 登録日 | 2016-09-01 | 公開日 | 2016-11-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.752 Å) | 主引用文献 | Structure of the MIND Complex Defines a Regulatory Focus for Yeast Kinetochore Assembly. Cell, 167, 2016
|
|
5TS0
| Structure of Mycobacterium tuberculosis proteasome in complex with N,C-capped dipeptide PKS2208 | 分子名称: | (2S)-N-{(2S)-3-methoxy-1-[(naphthalen-1-ylmethyl)amino]-1-oxopropan-2-yl}-4-oxo-2-[(3-phenylpropanoyl)amino]-4-(1H-pyrrol-1-yl)butanamide (non-preferred name), Proteasome subunit alpha, Proteasome subunit beta | 著者 | Hsu, H.-C, Fan, H, Singh, P.K, Wang, R, Sukenick, G, Nathan, C, Lin, G, Li, H. | 登録日 | 2016-10-27 | 公開日 | 2017-01-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.84679747 Å) | 主引用文献 | Structural Basis for the Species-Selective Binding of N,C-Capped Dipeptides to the Mycobacterium tuberculosis Proteasome. Biochemistry, 56, 2017
|
|
1I1X
| |
5TRS
| Structure of Mycobacterium tuberculosis proteasome in complex with N,C-capped dipeptide PKS2144 | 分子名称: | N-tert-butoxy-N~2~-(5-methyl-1,2-oxazole-3-carbonyl)-L-asparaginyl-O-methyl-N-[(naphthalen-1-yl)methyl]-L-serinamide, Proteasome subunit alpha, Proteasome subunit beta | 著者 | Hsu, H.-C, Fan, H, Singh, P.K, Wang, R, Sukenick, G, Nathan, C, Lin, G, Li, H. | 登録日 | 2016-10-27 | 公開日 | 2017-01-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.083567 Å) | 主引用文献 | Structural Basis for the Species-Selective Binding of N,C-Capped Dipeptides to the Mycobacterium tuberculosis Proteasome. Biochemistry, 56, 2017
|
|
1I94
| CRYSTAL STRUCTURES OF THE SMALL RIBOSOMAL SUBUNIT WITH TETRACYCLINE, EDEINE AND IF3 | 分子名称: | 16S RRNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | 著者 | Pioletti, M, Schluenzen, F, Harms, J, Zarivach, R, Gluehmann, M, Avila, H, Bartels, H, Jacobi, C, Hartsch, T, Yonath, A, Franceschi, F. | 登録日 | 2001-03-18 | 公開日 | 2001-04-12 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3. EMBO J., 20, 2001
|
|
8AXG
| Crystal structure of Fusobacterium nucleatum fusolisin protease | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Fusolisin, ... | 著者 | Isupov, M.N, Wiener, R, Rouvinski, A, Fahoum, J, Kumar, M, Read, R.J. | 登録日 | 2022-08-31 | 公開日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Crystal structure of Fusobacterium nucleatum fusolisin protease To Be Published
|
|
8AZC
| |
8AZD
| |