5TRS
Structure of Mycobacterium tuberculosis proteasome in complex with N,C-capped dipeptide PKS2144
Summary for 5TRS
Entry DOI | 10.2210/pdb5trs/pdb |
Related | 5TRG 5TRR 5TRY 5TS9 |
Related PRD ID | PRD_002256 |
Descriptor | Proteasome subunit alpha, Proteasome subunit beta, N-tert-butoxy-N~2~-(5-methyl-1,2-oxazole-3-carbonyl)-L-asparaginyl-O-methyl-N-[(naphthalen-1-yl)methyl]-L-serinamide, ... (4 entities in total) |
Functional Keywords | mycobacterium tuberculosis, proteasome, n, c-capped dipeptide, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Mycobacterium tuberculosis More |
Total number of polymer chains | 28 |
Total formula weight | 725197.84 |
Authors | Hsu, H.-C.,Fan, H.,Singh, P.K.,Wang, R.,Sukenick, G.,Nathan, C.,Lin, G.,Li, H. (deposition date: 2016-10-27, release date: 2017-01-11, Last modification date: 2024-03-06) |
Primary citation | Hsu, H.C.,Singh, P.K.,Fan, H.,Wang, R.,Sukenick, G.,Nathan, C.,Lin, G.,Li, H. Structural Basis for the Species-Selective Binding of N,C-Capped Dipeptides to the Mycobacterium tuberculosis Proteasome. Biochemistry, 56:324-333, 2017 Cited by PubMed: 27976853DOI: 10.1021/acs.biochem.6b01107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.08356699278 Å) |
Structure validation
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