7B5E
 
 | | Structure of calcium-bound mTMEM16A(ac)-I551A chloride channel at 4.1 A resolution | | 分子名称: | Anoctamin-1, CALCIUM ION | | 著者 | Lam, A.K.M, Rheinberger, J, Paulino, C, Dutzler, R. | | 登録日 | 2020-12-03 | | 公開日 | 2021-02-10 | | 最終更新日 | 2021-02-17 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Gating the pore of the calcium-activated chloride channel TMEM16A.
Nat Commun, 12, 2021
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5IYC
 | | Human core-PIC in the initial transcribing state | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | | 著者 | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | | 登録日 | 2016-03-24 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
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7AJR
 | | Virtual screening approach leading to the identification of a novel and tractable series of Pseudomonas aeruginosa elastase inhibitors | | 分子名称: | 2-[2-(1,3-benzothiazol-2-ylmethylcarbamoyl)-1,3-dihydroinden-2-yl]ethanoic acid, Keratinase KP2, SULFATE ION, ... | | 著者 | Leiris, S, Davies, D.T, Sprinsky, N, Castandet, J, Behria, L, Bodnarchuk, M.S, Sutton, J.M, Mullins, T.M.G, Jones, M.W, Forrest, A.K, Pallin, T.D, Karunakar, P, Martha, S.K, Parusharamulu, B, Ramula, R, Kotha, V, Pottabathini, N, Pothukanuri, S, Lemonnier, M, Everett, M. | | 登録日 | 2020-09-29 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Virtual Screening Approach to Identifying a Novel and Tractable Series of Pseudomonas aeruginosa Elastase Inhibitors.
Acs Med.Chem.Lett., 12, 2021
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7B5C
 | | Structure of calcium-bound mTMEM16A(ac) chloride channel at 3.7 A resolution | | 分子名称: | Anoctamin-1, CALCIUM ION | | 著者 | Lam, A.K.M, Rheinberger, J, Paulino, C, Dutzler, R. | | 登録日 | 2020-12-03 | | 公開日 | 2021-02-10 | | 最終更新日 | 2021-02-17 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Gating the pore of the calcium-activated chloride channel TMEM16A.
Nat Commun, 12, 2021
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8PR2
 | | Cytoplasmic dynein-1 heavy chain bound to JIP3-LZI | | 分子名称: | C-Jun-amino-terminal kinase-interacting protein 3, Cytoplasmic dynein 1 heavy chain 1, Cytoplasmic dynein 1 intermediate chain 2, ... | | 著者 | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | | 登録日 | 2023-07-12 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
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8PR1
 | | Cytoplasmic dynein-B heavy chain bound to IC-LC tower | | 分子名称: | Cytoplasmic dynein 1 heavy chain 1, Cytoplasmic dynein 1 intermediate chain 2, Cytoplasmic dynein 1 light intermediate chain 2, ... | | 著者 | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | | 登録日 | 2023-07-12 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (8.2 Å) | | 主引用文献 | Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
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8PQY
 | | Cytoplasmic dynein-1 motor domain bound to LIS1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ... | | 著者 | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | | 登録日 | 2023-07-12 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
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1FPM
 | | MONOVALENT CATION BINDING SITES IN N10-FORMYLTETRAHYDROFOLATE SYNTHETASE FROM MOORELLA THERMOACETICA | | 分子名称: | CESIUM ION, FORMATE--TETRAHYDROFOLATE LIGASE, SULFATE ION | | 著者 | Radfar, R, Leaphart, A, Brewer, J.M, Minor, W, Odom, J.D. | | 登録日 | 2000-08-31 | | 公開日 | 2001-08-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Cation binding and thermostability of FTHFS monovalent cation binding sites and thermostability of N10-formyltetrahydrofolate synthetase from Moorella thermoacetica.
Biochemistry, 39, 2000
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8PR0
 | | Cytoplasmic dynein-A heavy chain bound to dynactin-p150glued and IC-LC tower | | 分子名称: | Cytoplasmic dynein 1 heavy chain 1, Cytoplasmic dynein 1 intermediate chain 2, Cytoplasmic dynein 1 light intermediate chain 2, ... | | 著者 | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | | 登録日 | 2023-07-12 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (9.4 Å) | | 主引用文献 | Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
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4Y2L
 | | Structure of CFA/I pili major subunit CfaB trimer | | 分子名称: | CALCIUM ION, CFA/I fimbrial subunit B, ISOPROPYL ALCOHOL | | 著者 | Bao, R, Xia, D. | | 登録日 | 2015-02-10 | | 公開日 | 2016-08-10 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.746 Å) | | 主引用文献 | Off-pathway assembly of fimbria subunits is prevented by chaperone CfaA of CFA/I fimbriae from enterotoxigenic E. coli.
Mol. Microbiol., 102, 2016
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2JCN
 | | The crystal structure of BAK1 - a mitochondrial apoptosis regulator | | 分子名称: | BCL-2 HOMOLOGOUS ANTAGONIST/KILLER, SULFATE ION | | 著者 | Moche, M, Stenmark, P, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Johansson, I, Karlberg, T, Kosinska, U, Kotenyova, T, Lundgren, S, Nilsson, M.E, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Upsten, M, Thorsell, A.G, van den Berg, S, Weigelt, J, Nordlund, P, Structural Genomics Consortium (SGC) | | 登録日 | 2006-12-27 | | 公開日 | 2007-01-04 | | 最終更新日 | 2018-06-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The Crystal Structure of Bak1 - an Apoptosis Trigger in the Mitochondrial Outer Membrane
To be Published
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1OKQ
 | | LAMININ ALPHA 2 CHAIN LG4-5 DOMAIN PAIR, CA1 SITE MUTANT | | 分子名称: | CALCIUM ION, LAMININ ALPHA 2 CHAIN | | 著者 | Wizemann, H, Garbe, J.H.O, Friedrich, M.V.K, Timpl, R, Sasaki, T, Hohenester, E. | | 登録日 | 2003-07-28 | | 公開日 | 2003-09-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Distinct Requirements for Heparin and Alpha-Dystroglycan Binding Revealed by Structure-Based Mutagenesis of the Laminin Alpha2 Lg4-Lg5 Domain Pair
J.Mol.Biol., 332, 2003
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8PQV
 | | Cytoplasmic dynein-1 motor domain in post-powerstroke state | | 分子名称: | Cytoplasmic dynein 1 heavy chain 1 | | 著者 | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | | 登録日 | 2023-07-12 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
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5JGW
 | | Crystal structure of maize AKR4C13 in complex with NADP and acetate | | 分子名称: | ACETATE ION, Aldose reductase, AKR4C13, ... | | 著者 | Santos, M.L, Giuseppe, P.O, Kiyota, E, Sousa, S.M, Schmelz, E.A, Yunes, J.A, Koch, K.E, Murakami, M.T, Aparicio, R. | | 登録日 | 2016-04-20 | | 公開日 | 2017-05-03 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of maize AKR4C13 in complex with NADP and acetate
To Be Published
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5JHG
 | | Crystal structure of the complex between the human RhoA and the DH/PH domain of human ARHGEF11 | | 分子名称: | GLYCEROL, Rho guanine nucleotide exchange factor 11, Transforming protein RhoA | | 著者 | Wang, R, Chen, Q, Zhang, H, Yan, Z, Li, J, Miao, L, Wang, F. | | 登録日 | 2016-04-21 | | 公開日 | 2017-04-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA bound with its inhibitor and ARHGEF11
To Be Published
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1FMV
 | | CRYSTAL STRUCTURE OF THE APO MOTOR DOMAIN OF DICTYOSTELLIUM MYOSIN II | | 分子名称: | CHLORIDE ION, MYOSIN II HEAVY CHAIN | | 著者 | Bauer, C.B, Holden, H.M, Thoden, J.B, Smith, R, Rayment, I. | | 登録日 | 2000-08-18 | | 公開日 | 2000-11-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | X-ray structures of the apo and MgATP-bound states of Dictyostelium discoideum myosin motor domain.
J.Biol.Chem., 275, 2000
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8PR5
 | | Structure of the autoinhibited dynactin p150glued projection | | 分子名称: | Dynactin subunit 1 | | 著者 | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | | 登録日 | 2023-07-12 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (8.6 Å) | | 主引用文献 | Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
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1K0C
 | | Ure2p in complex with S-p-nitrobenzylglutathione | | 分子名称: | GLUTATHIONE, S-(P-NITROBENZYL)GLUTATHIONE, URE2 PROTEIN | | 著者 | Bousset, L, Belrhali, H, Melki, R, Morera, S. | | 登録日 | 2001-09-19 | | 公開日 | 2001-12-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of the yeast prion Ure2p functional region in complex with glutathione and related compounds.
Biochemistry, 40, 2001
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8PQZ
 | | Cytoplasmic dynein-1 A1/A2 motor domains bound to LIS1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ... | | 著者 | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | | 登録日 | 2023-07-12 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | | 主引用文献 | Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
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8PYR
 | | Crystal structure of the dual T-loop phosphorylated Cdk7/CycH/Mat1 complex | | 分子名称: | 1,2-ETHANEDIOL, CDK-activating kinase assembly factor MAT1, Cyclin-H, ... | | 著者 | Anand, K, Duster, R, Geyer, M. | | 登録日 | 2023-07-26 | | 公開日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural basis of Cdk7 activation by dual T-loop phosphorylation.
Biorxiv, 2024
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5JLP
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8PR3
 | | Cytoplasmic dynein-1 heavy chain bound to JIP3-RH1 | | 分子名称: | C-Jun-amino-terminal kinase-interacting protein 3, Cytoplasmic dynein 1 heavy chain 1, Cytoplasmic dynein 1 intermediate chain 2, ... | | 著者 | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | | 登録日 | 2023-07-12 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
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8PR4
 | | Dynactin pointed end bound to JIP3 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Arp11, C-Jun-amino-terminal kinase-interacting protein 3, ... | | 著者 | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | | 登録日 | 2023-07-12 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
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8PTK
 | | Composite structure of Dynein-Dynactin-JIP3-LIS1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ARP1 actin related protein 1 homolog A, ... | | 著者 | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | | 登録日 | 2023-07-14 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (10 Å) | | 主引用文献 | Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
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8PQW
 | | Cytoplasmic dynein-1 motor domain bound to dynactin-p150glued and LIS1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ... | | 著者 | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | | 登録日 | 2023-07-12 | | 公開日 | 2024-03-27 | | 最終更新日 | 2024-04-10 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
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