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PDB: 127 件
8CP4
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BU of 8cp4 by Molmil
[4Fe-4S] cluster containing LarE in complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, CHLORIDE ION, IRON/SULFUR CLUSTER, ...
著者Zecchin, P, Pecqueur, L, Golinelli-Pimpaneau, B.
登録日2023-03-01
公開日2024-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Structure-based insights into the mechanism of [4Fe-4S]-dependent sulfur insertase LarE.
Protein Sci., 33, 2024
4WFS
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BU of 4wfs by Molmil
Crystal Structure of tRNA-dihydrouridine(20) synthase catalytic domain
分子名称: CHLORIDE ION, FLAVIN MONONUCLEOTIDE, SULFATE ION, ...
著者Bou-Nader, C, Pecqueur, L, Kamah, A, Bregeon, D, Golinelli-Pimpaneau, B, Guimaraes, B.G, Fontecave, M, Hamdane, D.
登録日2014-09-17
公開日2015-10-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献An extended dsRBD is required for post-transcriptional modification in human tRNAs.
Nucleic Acids Res., 43, 2015
4WFT
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BU of 4wft by Molmil
Crystal structure of tRNA-dihydrouridine(20) synthase dsRBD domain
分子名称: tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
著者Bou-Nader, C, Pecqueur, L, Kamah, A, Bregeon, D, Golinelli-Pimpaneau, B, Guimaraes, B.G, Fontecave, M, Hamdane, D.
登録日2014-09-17
公開日2015-10-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献An extended dsRBD is required for post-transcriptional modification in human tRNAs.
Nucleic Acids Res., 43, 2015
5FRF
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BU of 5frf by Molmil
Solution structure of reduced and zinc-bound RsrA
分子名称: ANTI-SIGMA FACTOR RSRA, ZINC ION
著者Zdanowski, K, Pecqueur, L, Werner, J, Potts, J.R, Kleanthous, C.
登録日2015-12-17
公開日2016-08-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The Anti-Sigma Factor Rsra Responds to Oxidative Stress by Reburying its Hydrophobic Core.
Nat.Commun., 7, 2016
6EZA
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BU of 6eza by Molmil
Crystal Structure of human tRNA-dihydrouridine(20) synthase catalytic domain E294K mutant
分子名称: CHLORIDE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
著者Bou-Nader, C, Bregeon, D, Pecqueur, L, Vincent, G, Fontecave, M, Hamdane, D.
登録日2017-11-14
公開日2018-09-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases.
Biochemistry, 57, 2018
5FRH
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BU of 5frh by Molmil
Solution structure of oxidised RsrA
分子名称: ANTI-SIGMA FACTOR RSRA
著者Zdanowski, K, Pecqueur, L, Werner, J, Potts, J.R, Kleanthous, C.
登録日2015-12-17
公開日2016-08-03
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Anti-Sigma Factor Rsra Responds to Oxidative Stress by Reburying its Hydrophobic Core.
Nat.Commun., 7, 2016
7Z3Z
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BU of 7z3z by Molmil
Locked Wuhan SARS-CoV2 Prefusion Spike ectodomain with lipid bound
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, STEARIC ACID, ...
著者Duyvesteyn, H.M.E, Carrique, L, Ren, J, Stuart, D.I, Fry, E.E.
登録日2022-03-03
公開日2022-05-04
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The SARS-CoV-2 Spike harbours a lipid binding pocket which modulates stability of the prefusion trimer
bioRxiv, 2020
7NDZ
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BU of 7ndz by Molmil
ThyX reconstituted with N5-carbinolamine flavin
分子名称: DI(HYDROXYETHYL)ETHER, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, Flavin-dependent thymidylate synthase, ...
著者Bou-Nader, C, Pecqueur, L, Hamdane, D.
登録日2021-02-02
公開日2021-07-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An enzymatic activation of formaldehyde for nucleotide methylation.
Nat Commun, 12, 2021
7NDW
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BU of 7ndw by Molmil
ThyX-FADH2 soaked with 20 mM Formaldehyde
分子名称: DI(HYDROXYETHYL)ETHER, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, Flavin-dependent thymidylate synthase, ...
著者Bou-Nader, C, Pecqueur, L, Hamdane, D.
登録日2021-02-02
公開日2021-07-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献An enzymatic activation of formaldehyde for nucleotide methylation.
Nat Commun, 12, 2021
6Z97
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BU of 6z97 by Molmil
Structure of the prefusion SARS-CoV-2 spike glycoprotein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin
著者Duyvesteyn, H.M.E, Ren, J, Zhao, Y, Zhou, D, Huo, J, Carrique, L, Malinauskas, T, Ruza, R.R, Shah, P.N.M, Fry, E.E, Owens, R, Stuart, D.I.
登録日2020-06-03
公開日2020-07-01
最終更新日2020-09-23
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike.
Cell Host Microbe, 28, 2020
6Z43
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BU of 6z43 by Molmil
Cryo-EM Structure of SARS-CoV-2 Spike : H11-D4 Nanobody Complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody, ...
著者Ruza, R.R, Duyvesteyn, H.M.E, Shah, P, Carrique, L, Ren, J, Malinauskas, T, Zhou, D, Stuart, D.I, Naismith, J.H.
登録日2020-05-22
公開日2020-06-03
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for a potent neutralising single-domain antibody that blocks SARS-CoV-2 binding to its receptor ACE2
To Be Published
5LAD
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BU of 5lad by Molmil
Crystal Structure of apo HydF from thermotoga maritima
分子名称: Putative GTP-binding protein
著者Caserta, G, Pecqueur, L, Fontecave, M.
登録日2016-06-14
公開日2017-05-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and functional characterization of the hydrogenase-maturation HydF protein.
Nat. Chem. Biol., 13, 2017
6EZB
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BU of 6ezb by Molmil
Crystal Structure of human tRNA-dihydrouridine(20) synthase catalytic domain Q305K mutant
分子名称: FLAVIN MONONUCLEOTIDE, GLYCEROL, SULFATE ION, ...
著者Bou-Nader, C, Bregeon, D, Pecqueur, L, Fontecave, M, Hamdane, D.
登録日2017-11-14
公開日2018-09-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases.
Biochemistry, 57, 2018
6EI8
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BU of 6ei8 by Molmil
Crystal structure of human tRNA-dihydrouridine (20) synthase dsRBD F359A mutant
分子名称: SULFATE ION, tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
著者Bou-Nader, C, Pecqueur, L, Hamdane, D.
登録日2017-09-18
公開日2018-10-10
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Conformational Stability Adaptation of a Double-Stranded RNA-Binding Domain to Transfer RNA Ligand.
Biochemistry, 58, 2019
5KH0
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BU of 5kh0 by Molmil
Crystal Structure of HydF from thermosipho melanesiensis in complex with a [4Fe-4S] cluster
分子名称: IRON/SULFUR CLUSTER, Small GTP-binding protein
著者Caserta, G, Pecqueur, L, Fontecave, M.
登録日2016-06-14
公開日2017-05-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and functional characterization of the hydrogenase-maturation HydF protein.
Nat. Chem. Biol., 13, 2017
6QWL
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BU of 6qwl by Molmil
Influenza B virus (B/Panama/45) polymerase Hetermotrimer in complex with 3'5' cRNA promoter
分子名称: 3' cRNA, 5' cRNA, Polymerase acidic protein, ...
著者Keown, J.R, Carrique, L, Fan, H, Fodor, E, Grimes, J.M.
登録日2019-03-05
公開日2019-09-04
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structures of influenza A virus RNA polymerase offer insight into viral genome replication.
Nature, 573, 2019
8R60
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BU of 8r60 by Molmil
1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide
分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2023-11-19
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide
To Be Published
8R65
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BU of 8r65 by Molmil
1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide with ordered PB2 C-terminal domains
分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2023-11-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (4.23 Å)
主引用文献1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide with ordered PB2 C-terminal domains
To Be Published
7NHX
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BU of 7nhx by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer - full transcriptase (Class1)
分子名称: Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-11
公開日2021-12-01
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NK6
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BU of 7nk6 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8204
分子名称: Nb8204, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-17
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (6.72 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NIS
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BU of 7nis by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8192 core
分子名称: Nanobody8192 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-13
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (5.96 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NK1
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BU of 7nk1 by Molmil
1918 Influenza virus polymerase heterotirmer in complex with vRNA promoters and Nb8201
分子名称: Nanobody8201, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-17
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (4.22 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NJ7
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BU of 7nj7 by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8200 core
分子名称: Nb8200 core, Polymerase acidic protein, Polymerase basic protein 2,Immunoglobulin G-binding protein A, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-16
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (4.82 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NKI
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BU of 7nki by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8209 core
分子名称: Nb8209, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-18
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (4.67 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022
7NKA
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BU of 7nka by Molmil
1918 H1N1 Viral influenza polymerase heterotrimer with Nb8206
分子名称: NB8206, Polymerase acidic protein, Polymerase basic protein 2,Polymerase basic protein 2, ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2021-02-17
公開日2021-12-01
最終更新日2022-02-09
実験手法ELECTRON MICROSCOPY (4.07 Å)
主引用文献Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies.
Nat Commun, 13, 2022

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