6EZA

Crystal Structure of human tRNA-dihydrouridine(20) synthase catalytic domain E294K mutant

Summary for 6EZA

Entry DOI	10.2210/pdb6eza/pdb
Related	6EZB 6EZC
Descriptor	tRNA-dihydrouridine(20) synthase [NAD(P)+]-like, FLAVIN MONONUCLEOTIDE, SULFATE ION, ... (6 entities in total)
Functional Keywords	rna binding protein, trna processing, flavoprotein, oxidoreductase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	75547.14
Authors	Bou-Nader, C.,Bregeon, D.,Pecqueur, L.,Vincent, G.,Fontecave, M.,Hamdane, D. (deposition date: 2017-11-14, release date: 2018-09-26, Last modification date: 2024-01-17)
Primary citation	Bou-Nader, C.,Bregeon, D.,Pecqueur, L.,Fontecave, M.,Hamdane, D. Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases. Biochemistry, 57:5407-5414, 2018 Cited by PubMed: 30149704 DOI: 10.1021/acs.biochem.8b00584 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation