7WCM
| Cryo-EM structure of GPR119-Gs Complex with small molecule agonist MBX-2982 | 分子名称: | 2-[1-(5-ethylpyrimidin-2-yl)piperidin-4-yl]-4-[[4-(1,2,3,4-tetrazol-1-yl)phenoxy]methyl]-1,3-thiazole, Glucose-dependent insulinotropic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Qiao, A.N, Wu, S, Ye, S. | 登録日 | 2021-12-20 | 公開日 | 2022-12-21 | 最終更新日 | 2022-12-28 | 実験手法 | ELECTRON MICROSCOPY (2.33 Å) | 主引用文献 | Activation and signaling mechanism revealed by GPR119-G s complex structures. Nat Commun, 13, 2022
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7WCN
| Cryo-EM structure of GPR119-Gs Complex with small molecule agonist AR231453 | 分子名称: | Glucose-dependent insulinotropic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Qiao, A.N, Wu, S, Ye, S. | 登録日 | 2021-12-20 | 公開日 | 2022-12-21 | 最終更新日 | 2022-12-28 | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | 主引用文献 | Activation and signaling mechanism revealed by GPR119-G s complex structures. Nat Commun, 13, 2022
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6LML
| Cryo-EM structure of the human glucagon receptor in complex with Gi1 | 分子名称: | Glucagon, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Qiao, A, Han, S, Li, X, Sun, F, Zhao, Q, Wu, B. | 登録日 | 2019-12-26 | 公開日 | 2020-04-01 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis of Gsand Girecognition by the human glucagon receptor. Science, 367, 2020
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6LMK
| Cryo-EM structure of the human glucagon receptor in complex with Gs | 分子名称: | Glucagon, Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Qiao, A, Han, S, Tai, L, Sun, F, Zhao, Q, Wu, B. | 登録日 | 2019-12-26 | 公開日 | 2020-04-01 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural basis of Gsand Girecognition by the human glucagon receptor. Science, 367, 2020
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5YQZ
| Structure of the glucagon receptor in complex with a glucagon analogue | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glucagon analogue, ... | 著者 | Zhang, H, Qiao, A, Yang, L, VAN EPS, N, Frederiksen, K, Yang, D, Dai, A, Cai, X, Zhang, H, Yi, C, Can, C, He, L, Yang, H, Lau, J, Ernst, O, Hanson, M, Stevens, R, Wang, M, Seedtz-Runge, S, Jiang, H, Zhao, Q, Wu, B. | 登録日 | 2017-11-08 | 公開日 | 2018-01-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of the glucagon receptor in complex with a glucagon analogue. Nature, 553, 2018
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5XF1
| Structure of the Full-length glucagon class B G protein-coupled receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, H, Qiao, A, Yang, D, Yang, L, Dai, A, de Graaf, C, Reedtz-Runge, S, Dharmarajan, V, Zhang, H, Han, G.W, Grant, T, Sierra, R, Weierstall, U, Nelson, G, Liu, W, Wu, Y, Ma, L, Cai, X, Lin, G, Wu, X, Geng, Z, Dong, Y, Song, G, Griffin, P, Lau, J, Cherezov, V, Yang, H, Hanson, M, Stevens, R, Jiang, H, Wang, M, Zhao, Q, Wu, B. | 登録日 | 2017-04-06 | 公開日 | 2017-05-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | 主引用文献 | Structure of the full-length glucagon class B G-protein-coupled receptor. Nature, 546, 2017
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5XEZ
| Structure of the Full-length glucagon class B G protein-coupled receptor | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-{[(4-cyclohexylphenyl){[3-(methylsulfonyl)phenyl]carbamoyl}amino]methyl}-N-(1H-tetrazol-5-yl)benzamide, ... | 著者 | Zhang, H, Qiao, A, Yang, D, Yang, L, Dai, A, de Graaf, C, Reedtz-Runge, S, Dharmarajan, V, Zhang, H, Han, G.W, Grant, T, Sierra, R, Weierstall, U, Nelson, G, Liu, W, Wu, Y, Ma, L, Cai, X, Lin, G, Wu, X, Geng, Z, Dong, Y, Song, G, Griffin, P, Lau, J, Cherezov, V, Yang, H, Hanson, M, Stevens, R, Jiang, H, Wang, M, Zhao, Q, Wu, B. | 登録日 | 2017-04-06 | 公開日 | 2017-05-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of the full-length glucagon class B G-protein-coupled receptor. Nature, 546, 2017
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