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PDB: 116 results

1LME
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Crystal Structure of Peptide Deformylase from Thermotoga maritima
Descriptor: peptide deformylase
Authors:Kreusch, A, Spraggon, G, Lee, C.C, Klock, H, McMullan, D, Ng, K, Shin, T, Vincent, J, Warner, I, Ericson, C, Lesley, S.A, Joint Center for Structural Genomics (JCSG)
Deposit date:2002-05-01
Release date:2003-06-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure analysis of peptide deformylases from streptococcus pneumoniae,staphylococcus aureus, thermotoga maritima, and pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase
J.MOL.BIOL., 330, 2003
1LM6
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Crystal Structure of Peptide Deformylase from Streptococcus pneumoniae
Descriptor: FE (III) ION, GLYCEROL, peptide deformylase DEFB
Authors:Kreusch, A, Spraggon, G, Lee, C.C, Klock, H, McMullan, D, Ng, K, Shin, T, Vincent, J, Warner, I, Ericson, C, Lesley, S.A.
Deposit date:2002-04-30
Release date:2003-06-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure analysis of peptide deformylases from streptococcus pneumoniae,staphylococcus aureus, thermotoga maritima, and pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase
J.MOL.BIOL., 330, 2003
1N5N
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Crystal Structure of Peptide Deformylase from Pseudomonas aeruginosa
Descriptor: GLYCEROL, Peptide deformylase, ZINC ION
Authors:Kreusch, A, Spraggon, G, Lee, C.C, Klock, H, McMullan, D, Ng, K, Shin, T, Vincent, J, Warner, I, Ericson, C, Lesley, S.A.
Deposit date:2002-11-06
Release date:2003-06-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure analysis of peptide deformylases from streptococcus pneumoniae,staphylococcus aureus, thermotoga maritima, and pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase
J.MOL.BIOL., 330, 2003
1KGZ
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Crystal Structure Analysis of the Anthranilate Phosphoribosyltransferase from Erwinia carotovora (current name, Pectobacterium carotovorum)
Descriptor: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, MANGANESE (II) ION, ...
Authors:Kim, C, Xuong, N.-H, Edwards, S, Madhusudan, Yee, M.-C, Spraggon, G, Mills, S.E.
Deposit date:2001-11-28
Release date:2002-10-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structure of Anthranilate Phosphoribosyltransferase from the Enterobacterium Pectobacterium carotovorum
FEBS Lett., 523, 2002
1NH1
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Crystal Structure of the Type III Effector AvrB from Pseudomonas syringae.
Descriptor: Avirulence B protein
Authors:Lee, C.C, Wood, M.D, Ng, K, Luginbuhl, P, Spraggon, G, Katagiri, F.
Deposit date:2002-12-18
Release date:2004-03-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the Type III Effector AvrB from Pseudomonas syringae.
Structure, 12, 2004
1KEX
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Crystal Structure of the b1 Domain of Human Neuropilin-1
Descriptor: Neuropilin-1
Authors:Lee, C.C, Kreusch, A, McMullan, D, Ng, K, Spraggon, G.
Deposit date:2001-11-18
Release date:2003-01-28
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of the Human Neuropilin-1 b1 Domain
Structure, 11, 2003
1KHD
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Crystal Structure Analysis of the anthranilate phosphoribosyltransferase from Erwinia carotovora at 1.9 resolution (current name, Pectobacterium carotovorum)
Descriptor: Anthranilate phosphoribosyltransferase
Authors:Kim, C, Xuong, N.-H, Edwards, S, Madhusudan, Yee, M.-C, Spraggon, G, Mills, S.E.
Deposit date:2001-11-29
Release date:2002-10-23
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:The Crystal Structure of Anthranilate Phosphoribosyltransferase from the Enterobacterium Pectobacterium carotovorum
FEBS Lett., 523, 2002
1J7J
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Crystal Structure of the HPRT from Salmonella typhimurium
Descriptor: MAGNESIUM ION, hypoxanthine phosphoribosyltransferase
Authors:Lee, C.C, Focia, P.J, Spraggon, G, Eakin, A.E.
Deposit date:2001-05-16
Release date:2003-07-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the HPRT from Salmonella Typhimurium at 2.3 A Resolution
To be Published
1FZE
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CRYSTAL STRUCTURE OF FRAGMENT DOUBLE-D FROM HUMAN FIBRIN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN
Authors:Everse, S.J, Spraggon, G, Veerapandian, L, Doolittle, R.F.
Deposit date:1998-12-23
Release date:1999-06-08
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
Biochemistry, 38, 1999
1FZF
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CRYSTAL STRUCTURE OF FRAGMENT DOUBLE-D FROM HUMAN FIBRIN WITH THE PEPTIDE LIGAND GLY-HIS-ARG-PRO-AMIDE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN
Authors:Everse, S.J, Spraggon, G, Veerapandian, L, Doolittle, R.F.
Deposit date:1998-12-28
Release date:1999-06-08
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
Biochemistry, 38, 1999
1FZG
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CRYSTAL STRUCTURE OF FRAGMENT D FROM HUMAN FIBRINOGEN WITH THE PEPTIDE LIGAND GLY-HIS-ARG-PRO-AMIDE
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN
Authors:Everse, S.J, Spraggon, G, Veerapandian, L, Doolittle, R.F.
Deposit date:1999-01-01
Release date:1999-06-08
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
Biochemistry, 38, 1999
7RUN
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Crystal structure of phosphorylated RET tyrosine kinase domain complexed with a pyrrolo[2,3-d]pyrimidine inhibitor.
Descriptor: 1-(4-{(1s,3s)-3-[4-amino-5-(3-amino-4-chlorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl}piperazin-1-yl)ethan-1-one, CHLORIDE ION, Proto-oncogene tyrosine-protein kinase receptor Ret
Authors:Lee, C.C, Spraggon, G.
Deposit date:2021-08-17
Release date:2022-01-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.51 Å)
Cite:Antitarget Selectivity and Tolerability of Novel Pyrrolo[2,3- d ]pyrimidine RET Inhibitors.
Acs Med.Chem.Lett., 12, 2021
6VHG
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Crystal structure of phosphorylated RET tyrosine kinase domain complexed with a pyrazolo[1,5-a]pyrimidine inhibitor
Descriptor: 3-(3,4-dimethoxyphenyl)-N~5~-(1-methylpiperidin-4-yl)-6-phenylpyrazolo[1,5-a]pyrimidine-5,7-diamine, ACETATE ION, CHLORIDE ION, ...
Authors:Lee, C.C, Spraggon, G.
Deposit date:2020-01-09
Release date:2020-02-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:Efficacy and Tolerability of Pyrazolo[1,5-a]pyrimidine RET Kinase Inhibitors for the Treatment of Lung Adenocarcinoma.
Acs Med.Chem.Lett., 11, 2020
4MKC
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Crystal Structure of Anaplastic Lymphoma Kinase Complexed with LDK378
Descriptor: 5-chloro-N~2~-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N~4~-[2-(propan-2-ylsulfonyl)phenyl]pyrimidine-2,4-diamine, ALK tyrosine kinase receptor, GLYCEROL
Authors:Lee, C.C, Spraggon, G.
Deposit date:2013-09-04
Release date:2014-04-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:The ALK Inhibitor Ceritinib Overcomes Crizotinib Resistance in Non-Small Cell Lung Cancer.
Cancer Discov, 4, 2014
4Z55
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Anaplastic lymphoma kinase catalytic domain complexed with pyrazolopyrimidine derivative of LDK378
Descriptor: ALK tyrosine kinase receptor, GLYCEROL, N~6~-[5-methyl-4-(1-methylpiperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N~4~-[2-(propan-2-ylsulfonyl)phenyl]-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Authors:Lee, C.C, Spraggon, G.
Deposit date:2015-04-02
Release date:2016-02-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Design and synthesis of novel selective anaplastic lymphoma kinase inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
2Y7S
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Structure of a designed meningococcal antigen (factor H binding protein, mutant G1) inducing broad protective immunity
Descriptor: FACTOR H BINDING PROTEIN
Authors:Malito, E, Spraggon, G, Bottomley, M.J.
Deposit date:2011-02-01
Release date:2011-07-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rational Design of a Meningococcal Antigen Inducing Broad Protective Immunity.
Sci.Transl.Med, 3, 2011

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