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PDB: 116 件
1LME
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Crystal Structure of Peptide Deformylase from Thermotoga maritima
分子名称: peptide deformylase
著者Kreusch, A, Spraggon, G, Lee, C.C, Klock, H, McMullan, D, Ng, K, Shin, T, Vincent, J, Warner, I, Ericson, C, Lesley, S.A, Joint Center for Structural Genomics (JCSG)
登録日2002-05-01
公開日2003-06-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure analysis of peptide deformylases from streptococcus pneumoniae,staphylococcus aureus, thermotoga maritima, and pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase
J.MOL.BIOL., 330, 2003
1LM6
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Crystal Structure of Peptide Deformylase from Streptococcus pneumoniae
分子名称: FE (III) ION, GLYCEROL, peptide deformylase DEFB
著者Kreusch, A, Spraggon, G, Lee, C.C, Klock, H, McMullan, D, Ng, K, Shin, T, Vincent, J, Warner, I, Ericson, C, Lesley, S.A.
登録日2002-04-30
公開日2003-06-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure analysis of peptide deformylases from streptococcus pneumoniae,staphylococcus aureus, thermotoga maritima, and pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase
J.MOL.BIOL., 330, 2003
1N5N
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Crystal Structure of Peptide Deformylase from Pseudomonas aeruginosa
分子名称: GLYCEROL, Peptide deformylase, ZINC ION
著者Kreusch, A, Spraggon, G, Lee, C.C, Klock, H, McMullan, D, Ng, K, Shin, T, Vincent, J, Warner, I, Ericson, C, Lesley, S.A.
登録日2002-11-06
公開日2003-06-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure analysis of peptide deformylases from streptococcus pneumoniae,staphylococcus aureus, thermotoga maritima, and pseudomonas aeruginosa: snapshots of the oxygen sensitivity of peptide deformylase
J.MOL.BIOL., 330, 2003
1KGZ
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Crystal Structure Analysis of the Anthranilate Phosphoribosyltransferase from Erwinia carotovora (current name, Pectobacterium carotovorum)
分子名称: 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, MANGANESE (II) ION, ...
著者Kim, C, Xuong, N.-H, Edwards, S, Madhusudan, Yee, M.-C, Spraggon, G, Mills, S.E.
登録日2001-11-28
公開日2002-10-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Crystal Structure of Anthranilate Phosphoribosyltransferase from the Enterobacterium Pectobacterium carotovorum
FEBS Lett., 523, 2002
1NH1
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BU of 1nh1 by Molmil
Crystal Structure of the Type III Effector AvrB from Pseudomonas syringae.
分子名称: Avirulence B protein
著者Lee, C.C, Wood, M.D, Ng, K, Luginbuhl, P, Spraggon, G, Katagiri, F.
登録日2002-12-18
公開日2004-03-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of the Type III Effector AvrB from Pseudomonas syringae.
Structure, 12, 2004
1KEX
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Crystal Structure of the b1 Domain of Human Neuropilin-1
分子名称: Neuropilin-1
著者Lee, C.C, Kreusch, A, McMullan, D, Ng, K, Spraggon, G.
登録日2001-11-18
公開日2003-01-28
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of the Human Neuropilin-1 b1 Domain
Structure, 11, 2003
1KHD
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Crystal Structure Analysis of the anthranilate phosphoribosyltransferase from Erwinia carotovora at 1.9 resolution (current name, Pectobacterium carotovorum)
分子名称: Anthranilate phosphoribosyltransferase
著者Kim, C, Xuong, N.-H, Edwards, S, Madhusudan, Yee, M.-C, Spraggon, G, Mills, S.E.
登録日2001-11-29
公開日2002-10-23
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献The Crystal Structure of Anthranilate Phosphoribosyltransferase from the Enterobacterium Pectobacterium carotovorum
FEBS Lett., 523, 2002
1J7J
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Crystal Structure of the HPRT from Salmonella typhimurium
分子名称: MAGNESIUM ION, hypoxanthine phosphoribosyltransferase
著者Lee, C.C, Focia, P.J, Spraggon, G, Eakin, A.E.
登録日2001-05-16
公開日2003-07-29
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of the HPRT from Salmonella Typhimurium at 2.3 A Resolution
To be Published
1FZE
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CRYSTAL STRUCTURE OF FRAGMENT DOUBLE-D FROM HUMAN FIBRIN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN
著者Everse, S.J, Spraggon, G, Veerapandian, L, Doolittle, R.F.
登録日1998-12-23
公開日1999-06-08
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
Biochemistry, 38, 1999
1FZF
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CRYSTAL STRUCTURE OF FRAGMENT DOUBLE-D FROM HUMAN FIBRIN WITH THE PEPTIDE LIGAND GLY-HIS-ARG-PRO-AMIDE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN
著者Everse, S.J, Spraggon, G, Veerapandian, L, Doolittle, R.F.
登録日1998-12-28
公開日1999-06-08
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
Biochemistry, 38, 1999
1FZG
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BU of 1fzg by Molmil
CRYSTAL STRUCTURE OF FRAGMENT D FROM HUMAN FIBRINOGEN WITH THE PEPTIDE LIGAND GLY-HIS-ARG-PRO-AMIDE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FIBRINOGEN
著者Everse, S.J, Spraggon, G, Veerapandian, L, Doolittle, R.F.
登録日1999-01-01
公開日1999-06-08
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
Biochemistry, 38, 1999
7RUN
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Crystal structure of phosphorylated RET tyrosine kinase domain complexed with a pyrrolo[2,3-d]pyrimidine inhibitor.
分子名称: 1-(4-{(1s,3s)-3-[4-amino-5-(3-amino-4-chlorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutyl}piperazin-1-yl)ethan-1-one, CHLORIDE ION, Proto-oncogene tyrosine-protein kinase receptor Ret
著者Lee, C.C, Spraggon, G.
登録日2021-08-17
公開日2022-01-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.51 Å)
主引用文献Antitarget Selectivity and Tolerability of Novel Pyrrolo[2,3- d ]pyrimidine RET Inhibitors.
Acs Med.Chem.Lett., 12, 2021
6VHG
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Crystal structure of phosphorylated RET tyrosine kinase domain complexed with a pyrazolo[1,5-a]pyrimidine inhibitor
分子名称: 3-(3,4-dimethoxyphenyl)-N~5~-(1-methylpiperidin-4-yl)-6-phenylpyrazolo[1,5-a]pyrimidine-5,7-diamine, ACETATE ION, CHLORIDE ION, ...
著者Lee, C.C, Spraggon, G.
登録日2020-01-09
公開日2020-02-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Efficacy and Tolerability of Pyrazolo[1,5-a]pyrimidine RET Kinase Inhibitors for the Treatment of Lung Adenocarcinoma.
Acs Med.Chem.Lett., 11, 2020
4MKC
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Crystal Structure of Anaplastic Lymphoma Kinase Complexed with LDK378
分子名称: 5-chloro-N~2~-[5-methyl-4-(piperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N~4~-[2-(propan-2-ylsulfonyl)phenyl]pyrimidine-2,4-diamine, ALK tyrosine kinase receptor, GLYCEROL
著者Lee, C.C, Spraggon, G.
登録日2013-09-04
公開日2014-04-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献The ALK Inhibitor Ceritinib Overcomes Crizotinib Resistance in Non-Small Cell Lung Cancer.
Cancer Discov, 4, 2014
4Z55
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Anaplastic lymphoma kinase catalytic domain complexed with pyrazolopyrimidine derivative of LDK378
分子名称: ALK tyrosine kinase receptor, GLYCEROL, N~6~-[5-methyl-4-(1-methylpiperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N~4~-[2-(propan-2-ylsulfonyl)phenyl]-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
著者Lee, C.C, Spraggon, G.
登録日2015-04-02
公開日2016-02-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Design and synthesis of novel selective anaplastic lymphoma kinase inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
2Y7S
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Structure of a designed meningococcal antigen (factor H binding protein, mutant G1) inducing broad protective immunity
分子名称: FACTOR H BINDING PROTEIN
著者Malito, E, Spraggon, G, Bottomley, M.J.
登録日2011-02-01
公開日2011-07-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Rational Design of a Meningococcal Antigen Inducing Broad Protective Immunity.
Sci.Transl.Med, 3, 2011

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