5CYS
 
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6MRJ
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6AYL
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4XEG
 | | Structure of the enzyme-product complex resulting from TDG action on a G/hmU mismatch | | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, DNA (28-MER), ... | | 著者 | Pozharski, E, Malik, S.S, Drohat, A.C. | | 登録日 | 2014-12-23 | | 公開日 | 2015-09-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res., 43, 2015
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5HF7
 | | TDG enzyme-substrate complex | | 分子名称: | DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase | | 著者 | Pozharski, E, Malik, S.S, Drohat, A.C. | | 登録日 | 2016-01-06 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues.
Nucleic Acids Res., 44, 2016
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3UFJ
 | | Human Thymine DNA Glycosylase Bound to Substrate Analog 2'-fluoro-2'-deoxyuridine | | 分子名称: | 5'-D(*CP*AP*GP*CP*TP*CP*TP*GP*TP*AP*CP*GP*TP*GP*AP*GP*CP*AP*GP*TP*GP*GP*A)-3', 5'-D(*CP*CP*AP*CP*TP*GP*CP*TP*CP*AP*(UF2)P*GP*TP*AP*CP*AP*GP*AP*GP*CP*TP*GP*T)-3', G/T mismatch-specific thymine DNA glycosylase | | 著者 | Pozharski, E, Maiti, A, Drohat, A.C. | | 登録日 | 2011-11-01 | | 公開日 | 2012-04-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.967 Å) | | 主引用文献 | Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA.
Proc.Natl.Acad.Sci.USA, 109, 2012
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5FF8
 | | TDG enzyme-product complex | | 分子名称: | DNA, G/T mismatch-specific thymine DNA glycosylase | | 著者 | Pozharski, E, Malik, S.S, Drohat, A.C. | | 登録日 | 2015-12-18 | | 公開日 | 2016-09-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues.
Nucleic Acids Res., 44, 2016
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6X41
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6X6W
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6X6X
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6X6V
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6X6R
 | | Crystal structure of C.difficile ribosyltransferase CDTa in complex with pCl-phenylthioDADMeImmA | | 分子名称: | (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-{[(4-chlorophenyl)sulfanyl]methyl}pyrrolidin-3-ol, ADP-ribosyltransferase, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | | 著者 | Pozharski, E. | | 登録日 | 2020-05-29 | | 公開日 | 2021-10-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Crystal structure of C.difficile ribosyltransferase CDTa in complex with pCl-phenylthioDADMeImmA
To Be Published
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4Z7B
 | | Structure of the enzyme-product complex resulting from TDG action on a GfC mismatch | | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, DNA (28-MER), ... | | 著者 | Pozharski, E, Malik, S.S, Drohat, A.C. | | 登録日 | 2015-04-07 | | 公開日 | 2015-09-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res., 43, 2015
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4Z3A
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4Z7Z
 | | Structure of the enzyme-product complex resulting from TDG action on a GT mismatch in the presence of excess base | | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, DNA (28-MER), ... | | 著者 | Pozharski, E, Malik, S.S, Drohat, A.C. | | 登録日 | 2015-04-08 | | 公開日 | 2015-09-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res., 43, 2015
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4Z47
 | | Structure of the enzyme-product complex resulting from TDG action on a GU mismatch in the presence of excess base | | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, DNA, ... | | 著者 | Pozharski, E, Malik, S.S, Drohat, A.C. | | 登録日 | 2015-04-01 | | 公開日 | 2015-09-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res., 43, 2015
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2A1W
 | | Anti-cocaine antibody 7.5.21, crystal form I | | 分子名称: | SULFATE ION, immunoglobulin heavy chain, immunoglobulin light chain kappa | | 著者 | Pozharski, E, Hewagama, A, Shanafelt, A, Ringe, D, Petsko, G.A. | | 登録日 | 2005-06-21 | | 公開日 | 2005-06-28 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Flexibility Of Packing:
Four Crystal Forms Of An Anti-Cocaine Antibody 7.5.21
To be Published
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2A77
 | | Anti-Cocaine Antibody 7.5.21, Crystal Form II | | 分子名称: | GLYCEROL, Immunoglobulin Heavy Chain, Immunoglobulin Light Chain, ... | | 著者 | Pozharski, E, Hewagama, A, Shanafelt, A, Ringe, D, Petsko, G.A. | | 登録日 | 2005-07-04 | | 公開日 | 2005-07-12 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Flexibility of Packing: Four Crystal Forms of an Anti-Cocaine Antibody 7.5.21
To be Published
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2AI0
 | | Anti-Cocaine Antibody 7.5.21, Crystal Form III | | 分子名称: | GLYCEROL, Immunoglobulin Heavy Chain, Immunoglobulin Light Chain kappa, ... | | 著者 | Pozharski, E, Hewagama, A, Shanafelt, A, Ringe, D, Petsko, G.A. | | 登録日 | 2005-07-28 | | 公開日 | 2005-08-09 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Flexibility of Packing: Four Crystal Forms of an Anti-Cocaine Antibody 7.5.21
To be Published
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3LGH
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6UWI
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6UWO
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4GVA
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4GSB
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4GT3
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