1LUD
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![BU of 1lud by Molmil](/molmil-images/mine/1lud) | SOLUTION STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH TRIMETHOPRIM AND NADPH, 24 STRUCTURES | 分子名称: | 2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM, DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Polshakov, V.I, Smirnov, E.G, Birdsall, B, Kelly, G, Feeney, J. | 登録日 | 2002-05-22 | 公開日 | 2002-12-18 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH J.Biomol.Nmr, 24, 2002
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2MGT
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7QCB
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![BU of 7qcb by Molmil](/molmil-images/mine/7qcb) | Williams-Beuren syndrome related methyltransferase WBSCR27 in complex with SAH | 分子名称: | Methyltransferase-like 27, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Polshakov, V.I, Mariasina, S.S, Chang, C.-F, Efimov, S.V. | 登録日 | 2021-11-23 | 公開日 | 2021-12-29 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Williams-Beuren Syndrome Related Methyltransferase WBSCR27: From Structure to Possible Function. Front Mol Biosci, 9, 2022
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5LGF
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1YHO
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![BU of 1yho by Molmil](/molmil-images/mine/1yho) | Solution structure of human dihydrofolate reductase complexed with trimethoprim and nadph, 25 structures | 分子名称: | 2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Polshakov, V.I, Birdsall, B. | 登録日 | 2005-01-10 | 公開日 | 2005-11-22 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of human dihydrofolate reductase in its complex with trimethoprim and NADPH. J.Biomol.Nmr, 33, 2005
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7QCC
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1BZF
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![BU of 1bzf by Molmil](/molmil-images/mine/1bzf) | NMR SOLUTION STRUCTURE AND DYNAMICS OF THE COMPLEX OF LACTOBACILLUS CASEI DIHYDROFOLATE REDUCTASE WITH THE NEW LIPOPHILIC ANTIFOLATE DRUG TRIMETREXATE, 22 STRUCTURES | 分子名称: | DIHYDROFOLATE REDUCTASE, TRIMETREXATE | 著者 | Polshakov, V.I, Birdsall, B, Frenkiel, T.A, Gargaro, A.R, Feeney, J. | 登録日 | 1998-10-28 | 公開日 | 1999-05-18 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and dynamics in solution of the complex of Lactobacillus casei dihydrofolate reductase with the new lipophilic antifolate drug trimetrexate. Protein Sci., 8, 1999
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5LFY
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2LF1
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![BU of 2lf1 by Molmil](/molmil-images/mine/2lf1) | Solution structure of L. casei dihydrofolate reductase complexed with NADPH, 30 structures | 分子名称: | Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Polshakov, V, Feeney, J, Birdsall, B, Kovalevskaya, N. | 登録日 | 2011-06-28 | 公開日 | 2011-12-21 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structures of apo L. casei dihydrofolate reductase and its complexes with trimethoprim and NADPH: contributions to positive cooperative binding from ligand-induced refolding, conformational changes, and interligand hydrophobic interactions Biochemistry, 50, 2011
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2LI9
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![BU of 2li9 by Molmil](/molmil-images/mine/2li9) | Metal binding domain of rat beta-amyloid | 分子名称: | Amyloid beta A4 protein, ZINC ION | 著者 | Polshakov, V, Istrate, A, Kozin, S, Makarov, A. | 登録日 | 2011-08-25 | 公開日 | 2012-01-18 | 最終更新日 | 2012-03-21 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR solution structure of rat Abeta(1-16): toward understanding the mechanism of rats' resistance to Alzheimer's disease. Biophys.J., 102, 2012
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2L28
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![BU of 2l28 by Molmil](/molmil-images/mine/2l28) | Solution structure of lactobacillus casei dihydrofolate reductase apo-form, 25 conformers | 分子名称: | Dihydrofolate reductase | 著者 | Polshakov, V.I, Birdsall, B, Feeney, J. | 登録日 | 2010-08-13 | 公開日 | 2011-04-06 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Structures of Apo L. casei Dihydrofolate Reductase and Its Complexes with Trimethoprim and NADPH: Contributions to Positive Cooperative Binding from Ligand-Induced Refolding, Conformational Changes, and Interligand Hydrophobic Interactions. Biochemistry, 50, 2011
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2LLX
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2HM9
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![BU of 2hm9 by Molmil](/molmil-images/mine/2hm9) | Solution structure of dihydrofolate reductase complexed with trimethoprim, 33 structures | 分子名称: | 2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM, Dihydrofolate reductase | 著者 | Polshakov, V.I, Birdsall, B. | 登録日 | 2006-07-11 | 公開日 | 2007-06-05 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structures of apo L.casei dihydrofolate reductase and its complexes with trimethoprim and NADPH. Contributions to positive cooperative binding from ligand-induced refolding, conformational changes and interligand hydrophobic interactions Biochemistry, 2011
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2HST
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2HQP
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6Q44
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![BU of 6q44 by Molmil](/molmil-images/mine/6q44) | Est3 telomerase subunit in the yeast Hansenula polymorpha | 分子名称: | Uncharacterized protein | 著者 | Mantsyzov, A.B, Mariasina, S.S, Petrova, O.A, Efimov, S.V, Dontsova, O.A, Polshakov, V.I. | 登録日 | 2018-12-05 | 公開日 | 2019-12-25 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Insights into the structure and function of Est3 from the Hansenula polymorpha telomerase. Sci Rep, 10, 2020
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7NF9
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![BU of 7nf9 by Molmil](/molmil-images/mine/7nf9) | N-terminal C2H2 Zn-finger domain of Clamp | 分子名称: | Chromatin-linked adaptor for MSL proteins, isoform A, ZINC ION | 著者 | Mariasina, S.S, Bonchuk, A.N, Tikhonova, E.A, Efimov, S.V, Maksimenko, O.G, Georgiev, P.G, Polshakov, V.I. | 登録日 | 2021-02-05 | 公開日 | 2021-12-29 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for interaction between CLAMP and MSL2 proteins involved in the specific recruitment of the dosage compensation complex in Drosophila. Nucleic Acids Res., 50, 2022
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1PS2
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![BU of 1ps2 by Molmil](/molmil-images/mine/1ps2) | HIGH RESOLUTION NMR SOLUTION STRUCTURE OF HUMAN PS2, 19 STRUCTURES | 分子名称: | PS2 | 著者 | Williams, M.A, Polshakov, V.I, Gargaro, A.R, Feeney, J. | 登録日 | 1997-01-07 | 公開日 | 1997-07-07 | 最終更新日 | 2021-11-03 | 実験手法 | SOLUTION NMR | 主引用文献 | High-resolution solution structure of human pNR-2/pS2: a single trefoil motif protein. J.Mol.Biol., 267, 1997
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1DIS
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![BU of 1dis by Molmil](/molmil-images/mine/1dis) | DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEX WITH BRODIMOPRIM-4,6-DICARBOXYLATE | 分子名称: | BRODIMOPRIM-4,6-DICARBOXYLATE, DIHYDROFOLATE REDUCTASE | 著者 | Morgan, W.D, Birdsall, B, Polshakov, V.I, Sali, D, Kompis, I, Feeney, J. | 登録日 | 1995-08-01 | 公開日 | 1995-11-14 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a brodimoprim analogue in its complex with Lactobacillus casei dihydrofolate reductase. Biochemistry, 34, 1995
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1DIU
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![BU of 1diu by Molmil](/molmil-images/mine/1diu) | DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEX WITH BRODIMOPRIM-4,6-DICARBOXYLATE | 分子名称: | BRODIMOPRIM-4,6-DICARBOXYLATE, DIHYDROFOLATE REDUCTASE | 著者 | Morgan, W.D, Birdsall, B, Polshakov, V.I, Sali, D, Kompis, I, Feeney, J. | 登録日 | 1995-08-01 | 公開日 | 1995-11-14 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a brodimoprim analogue in its complex with Lactobacillus casei dihydrofolate reductase. Biochemistry, 34, 1995
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1AO8
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![BU of 1ao8 by Molmil](/molmil-images/mine/1ao8) | DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE, NMR, 21 STRUCTURES | 分子名称: | DIHYDROFOLATE REDUCTASE, METHOTREXATE | 著者 | Gargaro, A.R, Soteriou, A, Frenkiel, T.A, Bauer, C.J, Birdsall, B, Polshakov, V.I, Barsukov, I.L, Roberts, G.C.K, Feeney, J. | 登録日 | 1997-07-22 | 公開日 | 1998-02-25 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution structure of the complex of Lactobacillus casei dihydrofolate reductase with methotrexate. J.Mol.Biol., 277, 1998
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2KTU
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2KTV
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