4R4P
| Crystal Structure of the VS ribozyme-A756G mutant | 分子名称: | MAGNESIUM ION, VS ribozyme RNA | 著者 | Piccirilli, J.A, Suslov, N.B, Dasgupta, S, Huang, H, Lilley, D.M.J, Rice, P.A. | 登録日 | 2014-08-19 | 公開日 | 2015-09-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | 主引用文献 | Crystal structure of the Varkud satellite ribozyme. Nat.Chem.Biol., 11, 2015
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4R4V
| Crystal structure of the VS ribozyme - G638A mutant | 分子名称: | MAGNESIUM ION, POTASSIUM ION, VS ribozyme RNA | 著者 | Piccirilli, J.A, Suslov, N.B, Dasgupta, S, Huang, H, Lilley, D.M.J, Rice, P.A. | 登録日 | 2014-08-19 | 公開日 | 2015-09-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | 主引用文献 | Crystal structure of the Varkud satellite ribozyme. Nat.Chem.Biol., 11, 2015
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7U0Y
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8SH5
| Crystal structure of 3'cap-independent translation enhancers (CITE) from Pea enation mosaic virus RNA 2 (PEMV2) with Fab BL3-6K170A | 分子名称: | Fab BL3-6K170A heavy chain, Fab BL3-6K170A light chain, RNA (88-MER) | 著者 | Lewicka, A, Roman, C, Rice, P.A, Piccirilli, J.A. | 登録日 | 2023-04-13 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Crystal structure of a cap-independent translation enhancer RNA. Nucleic Acids Res., 51, 2023
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8UTA
| yjdF riboswitch from R. gauvreauii in complex with proflavine bound to Fab BL3-6 S97N | 分子名称: | Fab BL3-6 S97N heavy chain, Fab BL3-6 S97N light chain, MAGNESIUM ION, ... | 著者 | Krochmal, D, Lewicka, A, Piccirilli, J.A. | 登録日 | 2023-10-30 | 公開日 | 2024-04-10 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Structural basis for promiscuity in ligand recognition by yjdF riboswitch. Cell Discov, 10, 2024
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8UIW
| yjdF riboswitch from R. gauvreauii in complex with chelerythrine bound to Fab BL3-6 S97N | 分子名称: | 1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium, Fab BL3-6 S97N heavy chain, Fab BL3-6 S97N light chain, ... | 著者 | Krochmal, D, Lewicka, A, Piccirilli, J.A. | 登録日 | 2023-10-10 | 公開日 | 2024-04-10 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | Structural basis for promiscuity in ligand recognition by yjdF riboswitch. Cell Discov, 10, 2024
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5V3I
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5E08
| Specific Recognition of a Single-stranded RNA Sequence by an Engineered Synthetic Antibody Fragment | 分子名称: | Fab Heavy Chain, Fab Light Chain, RNA | 著者 | Huang, H, Qin, D, Li, N, Shao, Y, Staley, J.P, Kossiakoff, A.A, Koide, S, Piccirilli, J.A. | 登録日 | 2015-09-28 | 公開日 | 2016-09-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment. J.Mol.Biol., 428, 2016
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6B14
| Crystal structure of Spinach RNA aptamer in complex with Fab BL3-6S97N | 分子名称: | Heavy chain of Fab BL3-6S97N, Light chain of Fab BL3-6S97N, MAGNESIUM ION, ... | 著者 | DasGupta, S, Shelke, S.A, Piccirilli, J.A. | 登録日 | 2017-09-16 | 公開日 | 2017-12-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Affinity maturation of a portable Fab-RNA module for chaperone-assisted RNA crystallography. Nucleic Acids Res., 46, 2018
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6B3K
| Crystal structure of mutant Spinach RNA aptamer in complex with Fab BL3-6 | 分子名称: | Heavy chain of Fab BL3-6, Light chain of Fab BL3-6, MAGNESIUM ION, ... | 著者 | DasGupta, S, Koirala, D, Shelke, S.A, Piccirilli, J.A. | 登録日 | 2017-09-22 | 公開日 | 2017-12-27 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Affinity maturation of a portable Fab-RNA module for chaperone-assisted RNA crystallography. Nucleic Acids Res., 46, 2018
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6U8K
| Crystal structure of hepatitis C virus IRES junction IIIabc in complex with Fab HCV3 | 分子名称: | Heavy chain of Fab HCV3, JIIIabc RNA (68-MER), Light chain of Fab HCV3 | 著者 | Koirala, D, Lewicka, A, Koldobskaya, Y, Huang, H, Piccirilli, J.A. | 登録日 | 2019-09-05 | 公開日 | 2019-12-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Synthetic Antibody Binding to a Preorganized RNA Domain of Hepatitis C Virus Internal Ribosome Entry Site Inhibits Translation. Acs Chem.Biol., 15, 2020
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3OV6
| CD1c in complex with MPM (mannosyl-beta1-phosphomycoketide) | 分子名称: | 1-O-[(S)-hydroxy{[(4S,8S,16S,20S)-4,8,12,16,20-pentamethylheptacosyl]oxy}phosphoryl]-beta-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | 著者 | Scharf, L, Li, N.S, Hawk, A.J, Garzon, D, Zhang, T, Kazen, A.R, Shah, S, Haddadian, E.J, Saghatelian, A, Faraldo-Gomez, J.D, Meredith, S.C, Piccirilli, J.A, Adams, E.J. | 登録日 | 2010-09-15 | 公開日 | 2011-01-19 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | 主引用文献 | The 2.5 A structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation Immunity, 33, 2010
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6DB8
| Structural basis for promiscuous binding and activation of fluorogenic dyes by DIR2s RNA aptamer | 分子名称: | 2-[(Z)-(3-methyl-1,3-benzoxazol-2(3H)-ylidene)methyl]-3-(3-sulfopropyl)-1,3-benzothiazol-3-ium, Fab-Heavy chain, Fab-Light chain, ... | 著者 | Shao, Y, Shelke, S.A, Laski, A, Piccirilli, J.A. | 登録日 | 2018-05-02 | 公開日 | 2018-11-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.86541343 Å) | 主引用文献 | Structural basis for activation of fluorogenic dyes by an RNA aptamer lacking a G-quadruplex motif. Nat Commun, 9, 2018
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6DB9
| Structural basis for promiscuous binding and activation of fluorogenic dyes by DIR2s RNA aptamer | 分子名称: | Fab-Heavy-Chain, Fab-Light-Chain, MAGNESIUM ION, ... | 著者 | Shao, Y, Shelke, S.A, Laski, A, Piccirilli, J.A. | 登録日 | 2018-05-02 | 公開日 | 2018-11-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.025 Å) | 主引用文献 | Structural basis for activation of fluorogenic dyes by an RNA aptamer lacking a G-quadruplex motif. Nat Commun, 9, 2018
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6U8D
| Crystal structure of hepatitis C virus IRES junction IIIabc in complex with Fab HCV2 | 分子名称: | Heavy chain of Fab HCV2, JIIIabc RNA (68-MER), Light chain of Fab HCV2 | 著者 | Koirala, D, Lewicka, A, Koldobskaya, Y, Huang, H, Piccirilli, J.A. | 登録日 | 2019-09-04 | 公開日 | 2019-12-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.807 Å) | 主引用文献 | Synthetic Antibody Binding to a Preorganized RNA Domain of Hepatitis C Virus Internal Ribosome Entry Site Inhibits Translation. Acs Chem.Biol., 15, 2020
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6XJQ
| Crystal structure of a self-alkylating ribozyme - alkylated form with biotinylated epoxide substrate | 分子名称: | 2-{[(4R)-4-hydroxyhexyl]oxy}ethyl 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate, Fab HAVx Heavy Chain, Fab HAVx Light Chain, ... | 著者 | Koirala, D, Piccirilli, J.A. | 登録日 | 2020-06-24 | 公開日 | 2022-01-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.708 Å) | 主引用文献 | Structural basis for substrate binding and catalysis by a self-alkylating ribozyme. Nat.Chem.Biol., 18, 2022
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6XJW
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7SZU
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6MWN
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5C7W
| 5'-monophosphate Z:P Guanine Riboswitch bound to hypoxanthine. | 分子名称: | 5'-monophosphate Z:P guanine riboswitch, COBALT HEXAMMINE(III), HYPOXANTHINE | 著者 | Hernandez, A.R, Shao, Y, Hoshika, S, Yang, Z, Shelke, S.A, Herrou, J, Kim, H.-J, Kim, M.-J, Piccirilli, J.A, Benner, S.A. | 登録日 | 2015-06-25 | 公開日 | 2015-08-12 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | 主引用文献 | A Crystal Structure of a Functional RNA Molecule Containing an Artificial Nucleobase Pair. Angew.Chem.Int.Ed.Engl., 54, 2015
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5C7U
| 5'-monophosphate wt Guanine Riboswitch bound to hypoxanthine. | 分子名称: | 5'-monophosphate wt guanine riboswitch, COBALT HEXAMMINE(III), HYPOXANTHINE | 著者 | Hernandez, A.R, Shao, Y, Hoshika, S, Yang, Z, Shelke, S.A, Herrou, J, Kim, H.-J, Kim, M.-J, Piccirilli, J.A, Benner, S.A. | 登録日 | 2015-06-24 | 公開日 | 2015-08-12 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | A Crystal Structure of a Functional RNA Molecule Containing an Artificial Nucleobase Pair. Angew.Chem.Int.Ed.Engl., 54, 2015
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7JRS
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7JRR
| Crystal structures of artificially designed homomeric RNA nanoarchitectures | 分子名称: | MAGNESIUM ION, MANGANESE (II) ION, RNA (50-MER) | 著者 | Liu, D, Shao, Y, Piccirilli, J.A, Weizmann, Y. | 登録日 | 2020-08-12 | 公開日 | 2021-09-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Structures of artificially designed discrete RNA nanoarchitectures at near-atomic resolution. Sci Adv, 7, 2021
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7JRT
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6XJY
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