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PDB: 56 件

5JVU
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The neck-linker and alpha 7 helix of Drosophila melanogaster kinesin-1 fused to EB1
分子名称: 1,2-ETHANEDIOL, Chimera protein of Kinesin heavy chain and Microtubule-associated protein RP/EB family member 1
著者Phillips, R.K, Rayment, I.
登録日2016-05-11
公開日2016-08-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.948 Å)
主引用文献Family-specific Kinesin Structures Reveal Neck-linker Length Based on Initiation of the Coiled-coil.
J.Biol.Chem., 291, 2016
5JVR
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The neck-linker of Mus musculus KIF3A fused to the alpha 7 helix of Drosophila melanogaster Kinesin-1 fused to EB1
分子名称: Chimera protein of mouse KIF3A,fruit fly Kinesin-1 and human EB1
著者Phillips, R.K, Rayment, I.
登録日2016-05-11
公開日2016-08-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Family-specific Kinesin Structures Reveal Neck-linker Length Based on Initiation of the Coiled-coil.
J.Biol.Chem., 291, 2016
5JVM
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The neck-linker and alpha 7 helix of Mus musculus KIF3C
分子名称: Chimera protein of Kinesin-like protein KIF3C and Microtubule-associated protein RP/EB family member 1, MAGNESIUM ION
著者Phillips, R.K, Rayment, I.
登録日2016-05-11
公開日2016-08-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.567 Å)
主引用文献Family-specific Kinesin Structures Reveal Neck-linker Length Based on Initiation of the Coiled-coil.
J.Biol.Chem., 291, 2016
5JVP
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The neck-linker and alpha 7 helix of Homo sapiens CENP-E
分子名称: CADMIUM ION, Chimera protein of Centromere-associated protein E and Microtubule-associated protein RP/EB family member 1
著者Phillips, R.K, Rayment, I.
登録日2016-05-11
公開日2016-08-03
最終更新日2019-11-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Family-specific Kinesin Structures Reveal Neck-linker Length Based on Initiation of the Coiled-coil.
J.Biol.Chem., 291, 2016
5JX1
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The neck-linker and alpha 7 helix of Mus musculus KIF3A fused to EB1
分子名称: Chimera protein of Kinesin-like protein KIF3A and Microtubule-associated protein RP/EB family member 1
著者Phillips, R.K, Rayment, I.
登録日2016-05-12
公開日2016-08-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Family-specific Kinesin Structures Reveal Neck-linker Length Based on Initiation of the Coiled-coil.
J.Biol.Chem., 291, 2016
7LC0
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Structure of D-Glucosaminate-6-phosphate Ammonia-lyase
分子名称: ACETIC ACID, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Phillips, R.S.
登録日2021-01-09
公開日2021-06-09
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and Mechanism of d-Glucosaminate-6-phosphate Ammonia-lyase: A Novel Octameric Assembly for a Pyridoxal 5'-Phosphate-Dependent Enzyme, and Unprecedented Stereochemical Inversion in the Elimination Reaction of a d-Amino Acid.
Biochemistry, 60, 2021
7LCE
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Structure of D-Glucosaminate-6-phosphate Ammonia-lyase
分子名称: CALCIUM ION, D-glucosaminate-6-phosphate ammonia lyase, DIMETHYL SULFOXIDE
著者Phillips, R.S.
登録日2021-01-10
公開日2021-06-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structure and Mechanism of d-Glucosaminate-6-phosphate Ammonia-lyase: A Novel Octameric Assembly for a Pyridoxal 5'-Phosphate-Dependent Enzyme, and Unprecedented Stereochemical Inversion in the Elimination Reaction of a d-Amino Acid.
Biochemistry, 60, 2021
5JV3
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The neck-linker and alpha 7 helix of Homo sapiens Eg5 fused to EB1
分子名称: CALCIUM ION, Chimera protein of Kinesin-like protein KIF11 and Microtubule-associated protein RP/EB family member 1
著者Phillips, R.K, Rayment, I.
登録日2016-05-10
公開日2016-08-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献Family-specific Kinesin Structures Reveal Neck-linker Length Based on Initiation of the Coiled-coil.
J.Biol.Chem., 291, 2016
6DXV
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Citrobacter freundii tyrosine phenol-lyase F448A mutant
分子名称: POTASSIUM ION, Tyrosine phenol-lyase
著者Phillips, R.S.
登録日2018-07-01
公開日2018-10-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structures of Wild-Type and F448A Mutant Citrobacter freundii Tyrosine Phenol-Lyase Complexed with a Substrate and Inhibitors: Implications for the Reaction Mechanism.
Biochemistry, 57, 2018
6ECG
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Citrobacter freundii tyrosine phenol-lyase F448A mutant complexed with L-methionine
分子名称: (2E)-2-{[(Z)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4(1H)-YLIDENE}METHYL]IMINO}-4-(METHYLSULFANYL)BUTANOIC ACID, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, POTASSIUM ION, ...
著者Phillips, R.S.
登録日2018-08-07
公開日2018-10-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Crystal Structures of Wild-Type and F448A Mutant Citrobacter freundii Tyrosine Phenol-Lyase Complexed with a Substrate and Inhibitors: Implications for the Reaction Mechanism.
Biochemistry, 57, 2018
6DVX
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Citrobacter freundii tyrosine phenol-lyase F448A mutant complexed with L-phenylalanine
分子名称: (2E)-2-{[(Z)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4(1H)-ylidene}methyl]imino}-3-phenylpropanoic acid, (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-phenylalanine, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ...
著者Phillips, R.S.
登録日2018-06-25
公開日2018-10-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Crystal Structures of Wild-Type and F448A Mutant Citrobacter freundii Tyrosine Phenol-Lyase Complexed with a Substrate and Inhibitors: Implications for the Reaction Mechanism.
Biochemistry, 57, 2018
6DYT
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Citrobacter freundii tyrosine phenol-lyase F448A mutant complexed with L-alanine
分子名称: (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-alanine, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ALANYL-PYRIDOXAL-5'-PHOSPHATE, ...
著者Phillips, R.S.
登録日2018-07-02
公開日2018-10-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal Structures of Wild-Type and F448A Mutant Citrobacter freundii Tyrosine Phenol-Lyase Complexed with a Substrate and Inhibitors: Implications for the Reaction Mechanism.
Biochemistry, 57, 2018
6DZ5
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Citrobacter freundii tyrosine phenol-lyase F448A mutant complexed with L-alanine
分子名称: (2E)-3-(3-fluoro-4-hydroxyphenyl)-2-{[(Z)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4(1H)-ylidene}methyl]imino}propanoic acid, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, POTASSIUM ION, ...
著者Phillips, R.S.
登録日2018-07-03
公開日2018-10-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Crystal Structures of Wild-Type and F448A Mutant Citrobacter freundii Tyrosine Phenol-Lyase Complexed with a Substrate and Inhibitors: Implications for the Reaction Mechanism.
Biochemistry, 57, 2018
6DUR
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Citrobacter freundii tyrosine phenol-lyase complexed with L-phenylalanine
分子名称: (2E)-2-{[(Z)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4(1H)-ylidene}methyl]imino}-3-phenylpropanoic acid, (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-phenylalanine, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ...
著者Phillips, R.S.
登録日2018-06-21
公開日2018-10-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structures of Wild-Type and F448A Mutant Citrobacter freundii Tyrosine Phenol-Lyase Complexed with a Substrate and Inhibitors: Implications for the Reaction Mechanism.
Biochemistry, 57, 2018
5W19
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Tryptophan indole-lyase complex with oxindolyl-L-alanine
分子名称: 1-carboxy-1-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]azaniumyl}-2-[(3R)-2-oxo-2,3-dihydro-1H-indol-3-yl]ethan-1-ide, POTASSIUM ION, Tryptophanase
著者Phillips, R.S, Wood, Z.A.
登録日2017-06-02
公開日2018-06-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The crystal structure of Proteus vulgaris tryptophan indole-lyase complexed with oxindolyl-L-alanine: implications for the reaction mechanism.
Acta Crystallogr D Struct Biol, 74, 2018
5W1B
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Tryptophan indole-lyase
分子名称: POTASSIUM ION, Tryptophanase
著者Phillips, R.S, Wood, Z.A.
登録日2017-06-02
公開日2018-06-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of Proteus vulgaris tryptophan indole-lyase complexed with oxindolyl-L-alanine: implications for the reaction mechanism.
Acta Crystallogr D Struct Biol, 74, 2018
7UTC
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BU of 7utc by Molmil
Crystal structure of secondary alcohol dehydrogenases from the Thermoanaerobacter ethanolicus with NADP and transition-state analogue inhibitor DMSO
分子名称: DIMETHYL SULFOXIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Secondary-alcohol dehydrogenase, ...
著者Dinh, T, Phillips, R.
登録日2022-04-26
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystallographic snapshots of ternary complexes of thermophilic secondary alcohol dehydrogenase from Thermoanaerobacter pseudoethanolicus reveal the dynamics of ligand exchange and the proton relay network.
Proteins, 90, 2022
7UUT
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Ternary complex crystal structure of secondary alcohol dehydrogenases from the Thermoanaerobacter ethanolicus mutants C295A and I86A provides better understanding of catalytic mechanism
分子名称: (2R)-pentan-2-ol, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, ...
著者Dinh, T, Phillips, R, Rahn, K.
登録日2022-04-28
公開日2022-05-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Crystallographic snapshots of ternary complexes of thermophilic secondary alcohol dehydrogenase from Thermoanaerobacter pseudoethanolicus reveal the dynamics of ligand exchange and the proton relay network.
Proteins, 90, 2022
6XNB
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The Crystal Structure of the S154Y Mutant Carbonyl Reductase from Leifsonia xyli Explains Enhanced Activity for 3,5-Bis(trifluoromethyl)acetophenone Reduction
分子名称: MAGNESIUM ION, Short chain alcohol dehydrogenase
著者Dinh, T, Phillips, R.
登録日2020-07-02
公開日2020-08-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献The crystal structure of the S154Y mutant carbonyl reductase from Leifsonia xyli explains enhanced activity for 3,5-bis(trifluoromethyl)acetophenone reduction.
Arch.Biochem.Biophys., 720, 2022
3FDD
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BU of 3fdd by Molmil
The Crystal Structure of the Pseudomonas dacunhae Aspartate-Beta-Decarboxylase Reveals a Novel Oligomeric Assembly for a Pyridoxal-5-Phosphate Dependent Enzyme
分子名称: ACETATE ION, CHLORIDE ION, L-aspartate-beta-decarboxylase, ...
著者Lima, S, Sundararaju, B, Huang, C, Khristoforov, R, Momany, C, Phillips, R.S.
登録日2008-11-25
公開日2009-03-17
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The crystal structure of the Pseudomonas dacunhae aspartate-beta-decarboxylase dodecamer reveals an unknown oligomeric assembly for a pyridoxal-5'-phosphate-dependent enzyme.
J.Mol.Biol., 388, 2009
2YCP
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F448H mutant of tyrosine phenol-lyase from Citrobacter freundii in complex with quinonoid intermediate formed with 3-fluoro-L-tyrosine
分子名称: (2E)-3-(3-fluoro-4-hydroxyphenyl)-2-{[(Z)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4(1H)-ylidene}methyl]imino}propanoic acid, 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ...
著者Milic, D, Demidkina, T.V, Faleev, N.G, Phillips, R.S, Matkovic-Calogovic, D, Antson, A.A.
登録日2011-03-16
公開日2011-09-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystallographic Snapshots of Tyrosine Phenol-Lyase Show that Substrate Strain Plays a Role in C-C Bond Cleavage
J.Am.Chem.Soc., 133, 2011
2YCN
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Y71F mutant of tyrosine phenol-lyase from Citrobacter freundii in complex with quinonoid intermediate formed with 3-fluoro-L-tyrosine
分子名称: (2E)-3-(3-fluoro-4-hydroxyphenyl)-2-{[(Z)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4(1H)-ylidene}methyl]imino}propanoic acid, DI(HYDROXYETHYL)ETHER, POTASSIUM ION, ...
著者Milic, D, Demidkina, T.V, Faleev, N.G, Phillips, R.S, Matkovic-Calogovic, D, Antson, A.A.
登録日2011-03-16
公開日2011-09-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Crystallographic Snapshots of Tyrosine Phenol-Lyase Show that Substrate Strain Plays a Role in C-C Bond Cleavage
J.Am.Chem.Soc., 133, 2011
4NOD
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BU of 4nod by Molmil
Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation
分子名称: 5'-D(*CP*CP*AP*AP*CP*CP*AP*AP*GP*CP*CP*CP*CP*AP*TP*AP*CP*CP*CP*CP*AP*A)-3', 5'-D(*TP*TP*GP*GP*GP*GP*TP*AP*TP*GP*GP*GP*GP*CP*TP*TP*GP*GP*(BRU)P*TP*GP*G)-3', Transcription factor A, ...
著者Ngo, H.B, Lovely, G.A, Phillips, R, Chan, D.C.
登録日2013-11-19
公開日2014-01-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.897 Å)
主引用文献Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation.
Nat Commun, 5, 2014
2YCT
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Tyrosine phenol-lyase from Citrobacter freundii in complex with pyridine N-oxide and the quinonoid intermediate formed with L-alanine
分子名称: (2E)-2-{[(Z)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4(1H)-YLIDENE}METHYL]IMINO}PROPANOIC ACID, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, PHOSPHATE ION, ...
著者Milic, D, Demidkina, T.V, Faleev, N.G, Phillips, R.S, Matkovic-Calogovic, D, Antson, A.A.
登録日2011-03-16
公開日2011-09-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystallographic Snapshots of Tyrosine Phenol-Lyase Show that Substrate Strain Plays a Role in C-C Bond Cleavage
J.Am.Chem.Soc., 133, 2011
3E9K
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Crystal structure of Homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex
分子名称: 3-Hydroxyhippuric acid, Kynureninase, PYRIDOXAL-5'-PHOSPHATE
著者Lima, S, Kumar, S, Gawandi, V, Momany, C, Phillips, R.S.
登録日2008-08-22
公開日2008-12-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the Homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex: insights into the molecular basis of kynureninase substrate specificity.
J.Med.Chem., 52, 2009

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