3E9K

Crystal structure of Homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex

Summary for 3E9K

• Entry DOI: 10.2210/pdb3e9k/pdb
• Related: 1QZ9 2HZP
• Descriptor: Kynureninase, PYRIDOXAL-5'-PHOSPHATE, 3-Hydroxyhippuric acid, ... (4 entities in total)
• Functional Keywords: kynureninase, kynurenine-l-hydrolase, kynurenine hydrolase, pyridoxal-5'-phosphate, inhibitor complex, 3-hydroxy hippurate, 3-hydroxyhippuric acid, plp, pyridine nucleotide biosynthesis, pyridoxal phosphate, hydrolase
• Biological source: Homo sapiens
• Cellular location: Cytoplasm: Q16719
• Total number of polymer chains: 1
• Total formula weight: 52882.78

Authors

Lima, S.,Kumar, S.,Gawandi, V.,Momany, C.,Phillips, R.S. (deposition date: 2008-08-22, release date: 2008-12-09, Last modification date: 2023-08-30)

• Primary citation: Lima, S.,Kumar, S.,Gawandi, V.,Momany, C.,Phillips, R.S.; Crystal structure of the Homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex: insights into the molecular basis of kynureninase substrate specificity.; J.Med.Chem., 52:389-396, 2009; PubMed: 19143568; DOI: 10.1021/jm8010806

Experimental method

X-RAY DIFFRACTION (1.7 Å)