6NV8
Perdeuterated tyrosine phenol-lyase from Citrobacter freundii complexed with an aminoacrylate intermediate formed from S-ethyl-L-cysteine and 4-hydroxypyridine
Summary for 6NV8
Entry DOI | 10.2210/pdb6nv8/pdb |
Descriptor | Tyrosine phenol-lyase, POTASSIUM ION, pyridin-4-ol, ... (8 entities in total) |
Functional Keywords | pyridoxal-5'-phosphate, aminoacrylate intermediate, 4-hydroxypyridine, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Citrobacter freundii More |
Total number of polymer chains | 2 |
Total formula weight | 104454.84 |
Authors | Phillips, R.S. (deposition date: 2019-02-04, release date: 2020-02-12, Last modification date: 2023-11-15) |
Primary citation | Phillips, R.S.,Craig, S.,Kovalevsky, A.,Gerlits, O.,Weiss, K.,Iorgu, A.I.,Heyes, D.J.,Hay, S. Pressure and Temperature Effects on the Formation of Aminoacrylate Intermediates of Tyrosine Phenol-lyase Demonstrate Reaction Dynamics Acs Catalysis, 10:1692-1703, 2020 Cited by DOI: 10.1021/acscatal.9b03967PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.26 Å) |
Structure validation
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