6NV8

Perdeuterated tyrosine phenol-lyase from Citrobacter freundii complexed with an aminoacrylate intermediate formed from S-ethyl-L-cysteine and 4-hydroxypyridine

Summary for 6NV8

Entry DOI	10.2210/pdb6nv8/pdb
Descriptor	Tyrosine phenol-lyase, POTASSIUM ION, pyridin-4-ol, ... (8 entities in total)
Functional Keywords	pyridoxal-5'-phosphate, aminoacrylate intermediate, 4-hydroxypyridine, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
Biological source	Citrobacter freundii More
Total number of polymer chains	2
Total formula weight	104454.84
Authors	Phillips, R.S. (deposition date: 2019-02-04, release date: 2020-02-12, Last modification date: 2023-11-15)
Primary citation	Phillips, R.S.,Craig, S.,Kovalevsky, A.,Gerlits, O.,Weiss, K.,Iorgu, A.I.,Heyes, D.J.,Hay, S. Pressure and Temperature Effects on the Formation of Aminoacrylate Intermediates of Tyrosine Phenol-lyase Demonstrate Reaction Dynamics Acs Catalysis, 10:1692-1703, 2020 Cited by DOI: 10.1021/acscatal.9b03967 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.26 Å)

Structure validation