1CM7
 
 | | 3-ISOPROPYLMALATE DEHYDROGENASE FROM ESCHERICHIA COLI | | 分子名称: | PROTEIN (3-ISOPROPYLMALATE DEHYDROGENASE) | | 著者 | Wallon, G, Kryger, G, Lovett, S.T, Oshima, T, Ringe, D, Petsko, G.A. | | 登録日 | 1999-05-17 | | 公開日 | 1999-07-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Crystal structures of Escherichia coli and Salmonella typhimurium 3-isopropylmalate dehydrogenase and comparison with their thermophilic counterpart from Thermus thermophilus.
J.Mol.Biol., 266, 1997
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4HCW
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1ELC
 | | Analogous inhibitors of elastase do not always bind analogously | | 分子名称: | 6-ammonio-N-(trifluoroacetyl)-L-norleucyl-N-[4-(1-methylethyl)phenyl]-L-phenylalaninamide, CALCIUM ION, ELASTASE | | 著者 | Mattos, C, Rasmussen, B, Ding, X, Petsko, G.A, Ringe, D. | | 登録日 | 1993-12-07 | | 公開日 | 1994-04-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Analogous inhibitors of elastase do not always bind analogously.
Nat.Struct.Biol., 1, 1994
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5T1J
 | | Crystal Structure of the Tbox DNA binding domain of the transcription factor T-bet | | 分子名称: | DNA, T-box transcription factor TBX21 | | 著者 | Liu, C.F, Brandt, G.S, Hoang, Q, Hwang, E.S, Naumova, N, Lazarevic, V, Dekker, J, Glimcher, L.H, Ringe, D, Petsko, G.A. | | 登録日 | 2016-08-19 | | 公開日 | 2016-10-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.947 Å) | | 主引用文献 | Crystal structure of the DNA binding domain of the transcription factor T-bet suggests simultaneous recognition of distant genome sites.
Proc.Natl.Acad.Sci.USA, 113, 2016
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1QYG
 | | ANTI-COCAINE ANTIBODY M82G2 COMPLEXED WITH BENZOYLECGONINE | | 分子名称: | 3-(BENZOYLOXY)-8-METHYL-8-AZABICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID, FAB M82G2, HEAVY CHAIN, ... | | 著者 | Pozharski, E, Hewagama, A, Shanafelt, A, Petsko, G, Ringe, D. | | 登録日 | 2003-09-10 | | 公開日 | 2003-09-23 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Diversity in hapten recognition: structural study of an anti-cocaine antibody M82G2.
J.Mol.Biol., 349, 2005
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1WAL
 | | 3-ISOPROPYLMALATE DEHYDROGENASE (IPMDH) MUTANT (M219A)FROM THERMUS THERMOPHILUS | | 分子名称: | PROTEIN (3-ISOPROPYLMALATE DEHYDROGENASE) | | 著者 | Wallon, G, Kryger, G, Lovett, S.T, Oshima, T, Ringe, D, Petsko, G.A. | | 登録日 | 1999-05-17 | | 公開日 | 1999-05-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Crystal structures of Escherichia coli and Salmonella typhimurium 3-isopropylmalate dehydrogenase and comparison with their thermophilic counterpart from Thermus thermophilus.
J.Mol.Biol., 266, 1997
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1SOA
 | | Human DJ-1 with sulfinic acid | | 分子名称: | RNA-binding protein regulatory subunit; oncogene DJ1 | | 著者 | Canet-Aviles, R, Wilson, M.A, Miller, D.W, Ahmad, R, McLendon, C, Bandyopadhyay, S, Baptista, M.J, Ringe, D, Petsko, G.A, Cookson, M.R. | | 登録日 | 2004-03-13 | | 公開日 | 2004-06-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization.
Proc.Natl.Acad.Sci.USA, 101, 2004
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1DZ4
 | | ferric p450cam from pseudomonas putida | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, CYTOCHROME P450-CAM, ... | | 著者 | Schlichting, I, Berendzen, J, Chu, K, Stock, A.M, Maves, S.A, Benson, D.E, Sweet, R.M, Ringe, D, Petsko, G.A, Sligar, S.G. | | 登録日 | 2000-02-16 | | 公開日 | 2000-07-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The Catalytic Pathway of Cytochrome P450Cam at Atomic Resolution
Science, 287, 2000
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1A0G
 | | L201A MUTANT OF D-AMINO ACID AMINOTRANSFERASE COMPLEXED WITH PYRIDOXAMINE-5'-PHOSPHATE | | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, D-AMINO ACID AMINOTRANSFERASE | | 著者 | Sugio, S, Kashima, A, Kishimoto, K, Peisach, D, Petsko, G.A, Ringe, D, Yoshimura, T, Esaki, N. | | 登録日 | 1997-11-30 | | 公開日 | 1998-06-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of L201A mutant of D-amino acid aminotransferase at 2.0 A resolution: implication of the structural role of Leu201 in transamination.
Protein Eng., 11, 1998
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1BRM
 | | ASPARTATE BETA-SEMIALDEHYDE DEHYDROGENASE FROM ESCHERICHIA COLI | | 分子名称: | ASPARTATE-SEMIALDEHYDE DEHYDROGENASE | | 著者 | Hadfield, A.T, Kryger, G, Ouyang, J, Ringe, D, Petsko, G.A, Viola, R.E. | | 登録日 | 1998-08-24 | | 公開日 | 1999-06-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of aspartate-beta-semialdehyde dehydrogenase from Escherichia coli, a key enzyme in the aspartate family of amino acid biosynthesis.
J.Mol.Biol., 289, 1999
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1RXT
 | | Crystal structure of human myristoyl-CoA:protein N-myristoyltransferase. | | 分子名称: | COBALT (II) ION, Glycylpeptide N-tetradecanoyltransferase 1, SULFATE ION | | 著者 | Yang, J, Wang, Y, Frey, G, Abeles, R.H, Petsko, G.A, Ringe, D. | | 登録日 | 2003-12-18 | | 公開日 | 2005-04-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of human myristoyl-CoA:protein N-myristoyltransferase
To be Published
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2ACQ
 | | AN ANION BINDING SITE IN HUMAN ALDOSE REDUCTASE: MECHANISTIC IMPLICATIONS FOR THE BINDING OF CITRATE, CACODYLATE, AND GLUCOSE-6-PHOSPHATE | | 分子名称: | 6-O-phosphono-alpha-D-glucopyranose, ALDOSE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Harrison, D.H, Bohren, K.M, Gabbay, K.H, Petsko, G.A, Ringe, D. | | 登録日 | 1994-04-15 | | 公開日 | 1994-07-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | An anion binding site in human aldose reductase: mechanistic implications for the binding of citrate, cacodylate, and glucose 6-phosphate.
Biochemistry, 33, 1994
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2AB0
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2ACS
 | | AN ANION BINDING SITE IN HUMAN ALDOSE REDUCTASE: MECHANISTIC IMPLICATIONS FOR THE BINDING OF CITRATE, CACODYLATE, AND GLUCOSE-6-PHOSPHATE | | 分子名称: | ALDOSE REDUCTASE, CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Harrison, D.H, Bohren, K.M, Gabbay, K.H, Petsko, G.A, Ringe, D. | | 登録日 | 1994-04-15 | | 公開日 | 1994-07-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | An anion binding site in human aldose reductase: mechanistic implications for the binding of citrate, cacodylate, and glucose 6-phosphate.
Biochemistry, 33, 1994
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2ACR
 | | AN ANION BINDING SITE IN HUMAN ALDOSE REDUCTASE: MECHANISTIC IMPLICATIONS FOR THE BINDING OF CITRATE, CACODYLATE, AND GLUCOSE-6-PHOSPHATE | | 分子名称: | ALDOSE REDUCTASE, CACODYLATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Harrison, D.H, Bohren, K.M, Gabbay, K.H, Petsko, G.A, Ringe, D. | | 登録日 | 1994-04-15 | | 公開日 | 1994-07-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | An anion binding site in human aldose reductase: mechanistic implications for the binding of citrate, cacodylate, and glucose 6-phosphate.
Biochemistry, 33, 1994
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1BKH
 | | MUCONATE LACTONIZING ENZYME FROM PSEUDOMONAS PUTIDA | | 分子名称: | MUCONATE LACTONIZING ENZYME | | 著者 | Hasson, M.S, Schlichting, I, Moulai, J, Taylor, K, Barrett, W, Kenyon, G.L, Babbitt, P.C, Gerlt, J.A, Petsko, G.A, Ringe, D. | | 登録日 | 1998-07-07 | | 公開日 | 1998-10-21 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Evolution of an enzyme active site: the structure of a new crystal form of muconate lactonizing enzyme compared with mandelate racemase and enolase.
Proc.Natl.Acad.Sci.USA, 95, 1998
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1ESA
 | | DIRECT STRUCTURE OBSERVATION OF AN ACYL-ENZYME INTERMEDIATE IN THE HYDROLYSIS OF AN ESTER SUBSTRATE BY ELASTASE | | 分子名称: | CALCIUM ION, PORCINE PANCREATIC ELASTASE, SULFATE ION | | 著者 | Ding, X, Rasmussen, B, Petsko, G.A, Ringe, D. | | 登録日 | 1994-02-04 | | 公開日 | 1994-04-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Direct structural observation of an acyl-enzyme intermediate in the hydrolysis of an ester substrate by elastase.
Biochemistry, 33, 1994
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1EY3
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1PVN
 | | The crystal structure of the complex between IMP dehydrogenase catalytic domain and a transition state analogue MZP | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-CARBAMOYL-1-BETA-D-RIBOFURANOSYL-IMIDAZOLIUM-5-OLATE-5'-PHOSPHATE, Inosine-5'-monophosphate dehydrogenase, ... | | 著者 | Gan, L, Seyedsayamdost, M, Shuto, S, Matsuda, A, Petsko, G.A, Hedstrom, L. | | 登録日 | 2003-06-27 | | 公開日 | 2003-07-22 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Immunosuppressive Agent Mizoribine Monophosphate Forms a Transition State Analogue Complex with Inosine Monophosphate Dehydrogenase
Biochemistry, 42, 2003
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1Q0X
 | | Anti-morphine Antibody 9B1 Unliganded Form | | 分子名称: | Fab 9B1, heavy chain, light chain, ... | | 著者 | Pozharski, E, Wilson, M.A, Hewagama, A, Shanafelt, A.B, Petsko, G, Ringe, D. | | 登録日 | 2003-07-17 | | 公開日 | 2004-04-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Anchoring a cationic ligand: the structure of the Fab fragment of the anti-morphine antibody 9B1 and its complex with morphine
J.Mol.Biol., 337, 2004
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1OT5
 | | The 2.4 Angstrom Crystal Structure of Kex2 in complex with a peptidyl-boronic acid inhibitor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ac-Ala-Lys-boroArg N-acetylated boronic acid peptide inhibitor, ... | | 著者 | Holyoak, T, Wilson, M.A, Fenn, T.D, Kettner, C.A, Petsko, G.A, Fuller, R.S, Ringe, D. | | 登録日 | 2003-03-21 | | 公開日 | 2003-06-17 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | 2.4 A Resolution Crystal Structure of the Prototypical Hormone-Processing Protease Kex2 in Complex with an Ala-Lys-Arg Boronic Acid Inhibitor
Biochemistry, 42, 2003
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1Q0Y
 | | Anti-Morphine Antibody 9B1 Complexed with Morphine | | 分子名称: | (7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL, Fab 9B1, Heavy chain, ... | | 著者 | Pozharski, E, Wilson, M.A, Hewagama, A, Shanafelt, A.B, Petsko, G, Ringe, D. | | 登録日 | 2003-07-17 | | 公開日 | 2004-04-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Anchoring a cationic ligand: the structure of the Fab fragment of the anti-morphine antibody 9B1 and its complex with morphine
J.Mol.Biol., 337, 2004
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1R64
 | | The 2.2 A crystal structure of Kex2 protease in complex with Ac-Arg-Glu-Lys-boroArg peptidyl boronic acid inhibitor | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Holyoak, T, Kettner, C.A, Petsko, G.A, Fuller, R.S, Ringe, D. | | 登録日 | 2003-10-14 | | 公開日 | 2004-03-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Basis for Differences in Substrate Selectivity in Kex2 and Furin Protein Convertases
Biochemistry, 43, 2004
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1RE5
 | | Crystal structure of 3-carboxy-cis,cis-muconate lactonizing enzyme from Pseudomonas putida | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 3-carboxy-cis,cis-muconate cycloisomerase, CITRIC ACID | | 著者 | Yang, J, Wang, Y, Woolridge, E.M, Petsko, G.A, Kozarich, J.W, Ringe, D. | | 登録日 | 2003-11-06 | | 公開日 | 2004-06-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal Structure of 3-Carboxy-cis,cis-muconate Lactonizing Enzyme from Pseudomonas putida, a Fumarase Class II Type Cycloisomerase: Enzyme Evolution in Parallel Pathways.
Biochemistry, 43, 2004
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1RTQ
 | | The 0.95 Angstrom Resolution Crystal Structure of the Aminopeptidase from Aeromonas proteolytica | | 分子名称: | Bacterial leucyl aminopeptidase, SODIUM ION, THIOCYANATE ION, ... | | 著者 | Desmarais, W, Bienvenue, D.L, Krzysztof, B.P, Holz, R.C, Petsko, G.A, Ringe, D. | | 登録日 | 2003-12-10 | | 公開日 | 2004-02-10 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | | 主引用文献 | The high-resolution structures of the neutral and the low pH crystals of aminopeptidase from Aeromonas proteolytica.
J.Biol.Inorg.Chem., 11, 2006
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