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PDB: 137 件
5KA9
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Protein Tyrosine Phosphatase 1B L192A mutant in complex with TCS401, open state
分子名称: 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
著者Choy, M.S, Peti, W, Page, R.
登録日2016-06-01
公開日2017-03-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
Mol. Cell, 65, 2017
5K9W
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Protein Tyrosine Phosphatase 1B (1-301) in complex with TCS401, closed state
分子名称: 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
著者Choy, M.S, Peti, W, Page, R.
登録日2016-06-01
公開日2017-03-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
Mol. Cell, 65, 2017
5KA7
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BU of 5ka7 by Molmil
Protein Tyrosine Phosphatase 1B T178A mutant in complex with TCS401, closed state
分子名称: 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
著者Choy, M.S, Peti, W, Page, R.
登録日2016-06-01
公開日2017-03-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.061 Å)
主引用文献Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
Mol. Cell, 65, 2017
5KA0
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BU of 5ka0 by Molmil
Protein Tyrosine Phosphatase 1B Delta helix 7, open state
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ...
著者Choy, M.S, Peti, W, Page, R.
登録日2016-06-01
公開日2017-03-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.991 Å)
主引用文献Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
Mol. Cell, 65, 2017
5KAD
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BU of 5kad by Molmil
Protein Tyrosine Phosphatase 1B N193A mutant in complex with TCS401, closed state
分子名称: 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
著者Choy, M.S, Peti, W, Page, R.
登録日2016-06-01
公開日2017-03-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
Mol. Cell, 65, 2017
5K6S
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BU of 5k6s by Molmil
The structure of the PP2A B56 subunit BubR1 complex
分子名称: BubR1, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
著者Page, R, Wang, X, Bajaj, R, Peti, W.
登録日2016-05-25
公開日2016-12-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.794 Å)
主引用文献Expanding the PP2A Interactome by Defining a B56-Specific SLiM.
Structure, 24, 2016
5K9V
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BU of 5k9v by Molmil
Protein Tyrosine Phosphatase 1B (1-301), open state
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ...
著者Choy, M.S, Peti, W, Page, R.
登録日2016-06-01
公開日2017-03-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.898 Å)
主引用文献Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
Mol. Cell, 65, 2017
5KAA
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BU of 5kaa by Molmil
Protein Tyrosine Phosphatase 1B Delta helix 7, P185G mutant, open state
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ...
著者Choy, M.S, Machado, L.E.S.F, Peti, W, Page, R.
登録日2016-06-01
公開日2017-03-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.968 Å)
主引用文献Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
Mol. Cell, 65, 2017
5JPE
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BU of 5jpe by Molmil
Yeast-specific serine/threonine protein phosphatase (PPZ1) of Candida albicans
分子名称: CITRATE ANION, GLYCEROL, Serine/threonine-protein phosphatase
著者Choy, M.S, Chen, E.H, Peti, W, Page, R.
登録日2016-05-03
公開日2016-08-31
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.611 Å)
主引用文献Molecular Insights into the Fungus-Specific Serine/Threonine Protein Phosphatase Z1 in Candida albicans.
Mbio, 7, 2016
5KA4
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BU of 5ka4 by Molmil
Protein Tyrosine Phosphatase 1B T178A mutant, open state
分子名称: Tyrosine-protein phosphatase non-receptor type 1
著者Choy, M.S, Peti, W, Page, R.
登録日2016-06-01
公開日2017-03-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.185 Å)
主引用文献Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
Mol. Cell, 65, 2017
5KAB
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BU of 5kab by Molmil
Protein Tyrosine Phosphatase 1B Delta helix 7, P185G mutant in complex with TCS401, open state
分子名称: 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
著者Choy, M.S, Machado, L.E.S.F, Peti, W, Page, R.
登録日2016-06-01
公開日2017-03-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.968 Å)
主引用文献Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
Mol. Cell, 65, 2017
5KAC
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BU of 5kac by Molmil
Protein Tyrosine Phosphatase 1B P185G mutant, open state
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ...
著者Choy, M.S, Machado, L.E.S.F, Peti, W, Page, R.
登録日2016-06-01
公開日2017-03-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
Mol. Cell, 65, 2017
5KA2
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BU of 5ka2 by Molmil
Protein Tyrosine Phosphatase 1B YAYA (Y152A, Y153A) mutant, open state
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ...
著者Choy, M.S, Peti, W, Page, R.
登録日2016-06-01
公開日2017-03-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.071 Å)
主引用文献Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
Mol. Cell, 65, 2017
5KA3
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BU of 5ka3 by Molmil
Protein Tyrosine Phosphatase 1B YAYA (Y152A, Y153A) mutant in complex with TCS401, closed state
分子名称: 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
著者Choy, M.S, Peti, W, Page, R.
登録日2016-06-01
公開日2017-03-08
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.141 Å)
主引用文献Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
Mol. Cell, 65, 2017
5KA1
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BU of 5ka1 by Molmil
Protein Tyrosine Phosphatase 1B Delta helix 7 mutant in complex with TCS401, closed state
分子名称: 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
著者Choy, M.S, Peti, W, Page, R.
登録日2016-06-01
公開日2017-03-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
Mol. Cell, 65, 2017
7MNA
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BU of 7mna by Molmil
PTP1B 1-284 F225Y-R199N in complex with TCS401
分子名称: 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
著者Torgeson, K.R, Page, R, Peti, W.
登録日2021-04-30
公開日2022-05-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022
7MN7
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BU of 7mn7 by Molmil
PTP1B F225Y in complex with TCS401
分子名称: 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
著者Torgeson, K.R, Page, R, Peti, W.
登録日2021-04-30
公開日2022-05-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022
7MNE
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BU of 7mne by Molmil
PTP1B P206G mutation, open state
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ...
著者Torgeson, K.R, Page, R, Peti, W.
登録日2021-04-30
公開日2022-05-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022
7MKZ
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BU of 7mkz by Molmil
PTP1B F225Y mutant, open state
分子名称: CHLORIDE ION, GLYCEROL, Tyrosine-protein phosphatase non-receptor type 1
著者Torgeson, K.R, Page, R, Peti, W.
登録日2021-04-27
公開日2022-05-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022
7MNC
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BU of 7mnc by Molmil
PTP1B L204A
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Tyrosine-protein phosphatase non-receptor type 1
著者Torgeson, K.R, Page, R, Peti, W.
登録日2021-04-30
公開日2022-05-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022
7MNF
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BU of 7mnf by Molmil
PTP1B P206G in complex with TCS401
分子名称: 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
著者Torgeson, K.R, Page, R, Peti, W.
登録日2021-04-30
公開日2022-05-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022
7MND
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BU of 7mnd by Molmil
PTP1B L204A in complex with TCS401
分子名称: 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
著者Torgeson, K.R, Page, R, Peti, W.
登録日2021-04-30
公開日2022-05-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022
7MNB
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BU of 7mnb by Molmil
PTP1B F225Y-R199N-L195R in complex with TCS401
分子名称: 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, CHLORIDE ION, GLYCEROL, ...
著者Torgeson, K.R, Page, R, Peti, W.
登録日2021-04-30
公開日2022-05-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022
7MN9
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BU of 7mn9 by Molmil
PTP1B 1-284 F225Y-R199N
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ...
著者Torgeson, K.R, Page, R, Peti, W.
登録日2021-04-30
公開日2022-05-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022
7MOV
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BU of 7mov by Molmil
PTP1B 1-301 F225Y-R199N mutations
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ...
著者Torgeson, K.R, Page, R, Peti, W.
登録日2021-05-03
公開日2022-05-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022

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件を2024-05-29に公開中

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