Protein Tyrosine Phosphatase 1B Delta helix 7, open state

Summary for 5KA0

Related5K9V 5K9W 5KA4 5KA8 5KA9 5KAA 5KAB 5KAC 5KAD 5KA1 5KA2 5KA3 5KA7
DescriptorTyrosine-protein phosphatase non-receptor type 1, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... (5 entities in total)
Functional Keywordsprotein tyrosine phosphatase, hydrolase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight34250.9
Choy, M.S.,Peti, W.,Page, R. (deposition date: 2016-06-01, release date: 2017-03-01, Last modification date: 2019-12-25)
Primary citation
Choy, M.S.,Li, Y.,Machado, L.E.,Kunze, M.B.,Connors, C.R.,Wei, X.,Lindorff-Larsen, K.,Page, R.,Peti, W.
Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.
Mol. Cell, 65:644-658.e5, 2017
PubMed: 28212750 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2017.01.014
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2112 0.4% 0.4% 4.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-28