7MKZ

PTP1B F225Y mutant, open state

Summary for 7MKZ

Entry DOI	10.2210/pdb7mkz/pdb
Descriptor	Tyrosine-protein phosphatase non-receptor type 1, GLYCEROL, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	protein tyrosine phosphatase, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	36230.84
Authors	Torgeson, K.R.,Page, R.,Peti, W. (deposition date: 2021-04-27, release date: 2022-05-18, Last modification date: 2023-10-18)
Primary citation	Torgeson, K.R.,Clarkson, M.W.,Granata, D.,Lindorff-Larsen, K.,Page, R.,Peti, W. Conserved conformational dynamics determine enzyme activity. Sci Adv, 8:eabo5546-eabo5546, 2022 Cited by PubMed: 35921420 DOI: 10.1126/sciadv.abo5546 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation