1YSY
 
 | | NMR Structure of the nonstructural Protein 7 (nsP7) from the SARS CoronaVirus | | Descriptor: | Replicase polyprotein 1ab (pp1ab) (ORF1AB) | | Authors: | Peti, W, Herrmann, T, Johnson, M.A, Kuhn, P, Stevens, R.C, Wuthrich, K, Joint Center for Structural Genomics (JCSG) | | Deposit date: | 2005-02-09 | | Release date: | 2005-12-06 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structural genomics of the severe acute respiratory syndrome coronavirus: nuclear magnetic resonance structure of the protein nsP7.
J.Virol., 79, 2005
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1R73
 | | Solution Structure of TM1492, the L29 ribosomal protein from Thermotoga maritima | | Descriptor: | 50S ribosomal protein L29 | | Authors: | Peti, W, Etezady-Esfarjani, T, Herrmann, T, Klock, H.E, Lesley, S.A, Wuethrich, K, Joint Center for Structural Genomics (JCSG) | | Deposit date: | 2003-10-17 | | Release date: | 2004-08-10 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | NMR for structural proteomics of Thermotoga maritima: Screening and structure determination
J.STRUCT.FUNCT.GENOM., 5, 2004
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1RHX
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4P9F
 | | E. coli McbR/YncC | | Descriptor: | HTH-type transcriptional regulator mcbR | | Authors: | Lord, D.M, Page, R, Peti, W. | | Deposit date: | 2014-04-03 | | Release date: | 2015-01-14 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.099 Å) | | Cite: | McbR/YncC: Implications for the Mechanism of Ligand and DNA Binding by a Bacterial GntR Transcriptional Regulator Involved in Biofilm Formation.
Biochemistry, 53, 2014
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5INB
 | | RepoMan-PP1g (protein phosphatase 1, gamma isoform) holoenzyme complex | | Descriptor: | Cell division cycle-associated protein 2, GLYCEROL, MALONATE ION, ... | | Authors: | Kumar, G.S, Peti, W, Page, R. | | Deposit date: | 2016-03-07 | | Release date: | 2016-10-05 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism.
Elife, 5, 2016
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4PHL
 | | TbrPDEB1-inhibitor complex | | Descriptor: | 3-(CYCLOPENTYLOXY)-N-(3,5-DICHLOROPYRIDIN-4-YL)-4-METHOXYBENZAMIDE, Class 1 phosphodiesterase PDEB1, ETHANOL, ... | | Authors: | Choy, M.S, Bland, N, Peti, W, Page, R. | | Deposit date: | 2014-05-06 | | Release date: | 2015-05-20 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | TbrPDEB1-inhibitor complex
To Be Published
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2G5M
 | | Spinophilin PDZ domain | | Descriptor: | Neurabin-2 | | Authors: | Kelker, M.S, Peti, W. | | Deposit date: | 2006-02-23 | | Release date: | 2007-01-09 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structural basis for spinophilin-neurabin receptor interaction.
Biochemistry, 46, 2007
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2FN5
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7T0Y
 | | The Ribosomal RNA Processing 1B Protein Phosphatase-1 Holoenzyme | | Descriptor: | 1,2-ETHANEDIOL, BROMIDE ION, FLUORIDE ION, ... | | Authors: | Srivastava, G, Page, R, Peti, W. | | Deposit date: | 2021-11-30 | | Release date: | 2022-12-07 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The ribosomal RNA processing 1B:protein phosphatase 1 holoenzyme reveals non-canonical PP1 interaction motifs.
Cell Rep, 41, 2022
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6HKW
 | | Crystal structure of human SDS22 | | Descriptor: | Protein phosphatase 1 regulatory subunit 7, SULFATE ION | | Authors: | Heroes, E, Choy, M.S, Page, R, Peti, W, Ulens, C, Van Meervelt, L, Nys, M, Bollen, M. | | Deposit date: | 2018-09-09 | | Release date: | 2019-01-30 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (3.09 Å) | | Cite: | Structure-Guided Exploration of SDS22 Interactions with Protein Phosphatase PP1 and the Splicing Factor BCLAF1.
Structure, 27, 2019
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1OJG
 | | Sensory domain of the membraneous two-component fumarate sensor DcuS of E. coli | | Descriptor: | SENSOR PROTEIN DCUS | | Authors: | Pappalardo, L, Janausch, I.G, Vijayan, V, Zientz, E, Junker, J, Peti, W, Zweckstetter, M, Unden, G, Griesinger, C. | | Deposit date: | 2003-07-10 | | Release date: | 2003-08-15 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The NMR structure of the sensory domain of the membranous two-component fumarate sensor (histidine protein kinase) DcuS of Escherichia coli.
J. Biol. Chem., 278, 2003
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3HVQ
 | | Crystal structure of a complex between Protein Phosphatase 1 alpha (PP1) and the PP1 binding and PDZ domains of Neurabin | | Descriptor: | GLYCEROL, MANGANESE (II) ION, Neurabin-1, ... | | Authors: | Critton, D.A, Ragusa, M.J, Page, R, Peti, W. | | Deposit date: | 2009-06-16 | | Release date: | 2010-03-23 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites.
Nat.Struct.Mol.Biol., 17, 2010
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6OBR
 | | PP1 Y134A in complex with Microcystin LR | | Descriptor: | CHLORIDE ION, MANGANESE (II) ION, Microcystin LR, ... | | Authors: | Choy, M.S, Moon, T.M, Bray, J.A, Archuleta, T.L, Shi, W, Peti, W, Page, R. | | Deposit date: | 2019-03-21 | | Release date: | 2019-09-18 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | SDS22 selectively recognizes and traps metal-deficient inactive PP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
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6OBS
 | | PP1 Y134K | | Descriptor: | GLYCEROL, MANGANESE (II) ION, PHOSPHATE ION, ... | | Authors: | Choy, M.S, Moon, T.M, Bray, J.A, Archuleta, T.L, Shi, W, Peti, W, Page, R. | | Deposit date: | 2019-03-21 | | Release date: | 2019-09-18 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.803 Å) | | Cite: | SDS22 selectively recognizes and traps metal-deficient inactive PP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
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4XPN
 | | Crystal Structure of Protein Phosphate 1 complexed with PP1 binding domain of GADD34 | | Descriptor: | GLYCEROL, MANGANESE (II) ION, PHOSPHATE ION, ... | | Authors: | Choy, M.S, Peti, W, Page, R. | | Deposit date: | 2015-01-17 | | Release date: | 2015-07-01 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.285 Å) | | Cite: | Structural and Functional Analysis of the GADD34:PP1 eIF2 alpha Phosphatase.
Cell Rep, 11, 2015
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3V4Y
 | | Crystal Structure of the first Nuclear PP1 holoenzyme | | Descriptor: | GLYCEROL, MANGANESE (II) ION, Nuclear inhibitor of protein phosphatase 1, ... | | Authors: | Page, R, Peti, W, O'Connell, N.E, Nichols, S. | | Deposit date: | 2011-12-15 | | Release date: | 2012-10-31 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.098 Å) | | Cite: | The Molecular Basis for Substrate Specificity of the Nuclear NIPP1:PP1 Holoenzyme.
Structure, 20, 2012
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6UUQ
 | | Structure of Calcineurin bound to RCAN1 | | Descriptor: | Calcipressin-1, FE (III) ION, PHOSPHATE ION, ... | | Authors: | Sheftic, S, Page, R, Peti, W. | | Deposit date: | 2019-10-31 | | Release date: | 2020-09-09 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.849 Å) | | Cite: | The structure of the RCAN1:CN complex explains the inhibition of and substrate recruitment by calcineurin.
Sci Adv, 6, 2020
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3O9X
 | | Structure of the E. coli antitoxin MqsA (YgiT/b3021) in complex with its gene promoter | | Descriptor: | DNA (26-MER), GLYCEROL, Uncharacterized HTH-type transcriptional regulator ygiT, ... | | Authors: | Brown, B.L, Peti, W, Page, R. | | Deposit date: | 2010-08-04 | | Release date: | 2010-11-10 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.0999 Å) | | Cite: | Structure of the Escherichia coli Antitoxin MqsA (YgiT/b3021) Bound to Its Gene Promoter Reveals Extensive Domain Rearrangements and the Specificity of Transcriptional Regulation.
J.Biol.Chem., 286, 2011
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6VRO
 | | The structure of the PP2A B56 subunit AIM1 complex | | Descriptor: | Beta/gamma crystallin domain-containing protein 1, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform | | Authors: | Wang, X, Page, R, Peti, W. | | Deposit date: | 2020-02-08 | | Release date: | 2020-03-25 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment.
Elife, 9, 2020
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1WCJ
 | | Conserved Hypothetical Protein TM0487 from Thermotoga maritima | | Descriptor: | HYPOTHETICAL PROTEIN TM0487 | | Authors: | Almeida, M.S, Peti, W, Herrmann, T, Wuthrich, K, Joint Center for Structural Genomics (JCSG) | | Deposit date: | 2004-11-17 | | Release date: | 2004-12-14 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | NMR Structure of the Conserved Hypothetical Protein Tm0487 from Thermotoga Maritima: Implications for 216 Homologous Duf59 Proteins.
Protein Sci., 14, 2005
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4Y14
 | | Structure of protein tyrosine phosphatase 1B complexed with inhibitor (PTP1B:CPT157633) | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-bromo-4-[difluoro(phosphono)methyl]-N-methyl-Nalpha-(methylsulfonyl)-L-phenylalaninamide, CHLORIDE ION, ... | | Authors: | Choy, M.S, Connors, C, Page, R, Peti, W. | | Deposit date: | 2015-02-06 | | Release date: | 2015-08-05 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.898 Å) | | Cite: | PTP1B inhibition suggests a therapeutic strategy for Rett syndrome.
J.Clin.Invest., 125, 2015
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6OYL
 | | The structure of the PP2A B56 subunit KIF4A complex | | Descriptor: | Chromosome-associated kinesin KIF4A, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform | | Authors: | Wang, X, Page, R, Peti, W. | | Deposit date: | 2019-05-14 | | Release date: | 2020-03-25 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment.
Elife, 9, 2020
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4F0Z
 | | Crystal Structure of Calcineurin in Complex with the Calcineurin-Inhibiting Domain of the African Swine Fever Virus Protein A238L | | Descriptor: | Ankyrin repeat domain-containing protein A238L, CALCIUM ION, Calcineurin subunit B type 1, ... | | Authors: | Grigoriu, S, Peti, W, Page, R. | | Deposit date: | 2012-05-05 | | Release date: | 2013-03-06 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The molecular mechanism of substrate engagement and immunosuppressant inhibition of calcineurin.
Plos Biol., 11, 2013
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4EWI
 | | Crystal structure of the NLRP4 Pyrin domain | | Descriptor: | CHLORIDE ION, NACHT, LRR and PYD domains-containing protein 4, ... | | Authors: | Eibl, C, Hessenberger, M, Puehringer, S, Page, R, Diederichs, K, Peti, W. | | Deposit date: | 2012-04-27 | | Release date: | 2012-09-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Structural and Functional Analysis of the NLRP4 Pyrin Domain.
Biochemistry, 51, 2012
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8SW6
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