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PDB: 120 件
5WBI
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BU of 5wbi by Molmil
Crystal structure of the Arabidopsis thaliana Raptor
分子名称: Regulatory-associated protein of TOR 1
著者Pavletich, N.P, Jiang, X.
登録日2017-06-29
公開日2017-12-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
Nature, 552, 2017
5WBU
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BU of 5wbu by Molmil
Crystal structure of mTOR(deltaN)-mLST8-PRAS40(alpha-helix & beta-strand) complex
分子名称: Proline-rich AKT1 substrate 1, Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8
著者Pavletich, N.P, Yang, H.
登録日2017-06-29
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
Nature, 552, 2017
5WBJ
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BU of 5wbj by Molmil
Crystal structure of the arabidopsis thaliana Raptor in complex with the TOS peptide of human 4EBP1
分子名称: Eukaryotic translation initiation factor 4E-binding protein 1, Regulatory-associated protein of TOR 1
著者Pavletich, N.P, Jiang, X.
登録日2017-06-29
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
Nature, 552, 2017
5WBY
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BU of 5wby by Molmil
Crystal structure of mTOR(deltaN)-mLST8-PRAS40(beta-strand) complex
分子名称: Proline-rich AKT1 substrate 1, Serine/threonine-protein kinase mTOR, Target of rapamycin complex subunit LST8
著者Pavletich, N.P, Yang, H.
登録日2017-06-29
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
Nature, 552, 2017
2GLI
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BU of 2gli by Molmil
FIVE-FINGER GLI/DNA COMPLEX
分子名称: COBALT (II) ION, DNA (5'-D(*AP*CP*GP*TP*GP*GP*AP*CP*CP*AP*CP*CP*CP*AP*AP*GP*AP*CP*GP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*CP*GP*TP*CP*TP*TP*GP*GP*GP*TP*GP*GP*TP*CP*CP*AP*CP*G)-3'), ...
著者Pavletich, N.P, Pabo, C.O.
登録日1993-11-09
公開日1993-11-09
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers.
Science, 261, 1993
6BCX
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BU of 6bcx by Molmil
mTORC1 structure refined to 3.0 angstroms
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E-binding protein 1, MAGNESIUM ION, ...
著者Pavletich, N.P, Yang, H.
登録日2017-10-20
公開日2017-12-20
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
Nature, 552, 2017
6BCU
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BU of 6bcu by Molmil
Cryo-EM structure of the activated RHEB-mTORC1 refined to 3.4 angstrom
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E-binding protein 1, GTP-binding protein Rheb, ...
著者Pavletich, N.P, Yang, H.
登録日2017-10-20
公開日2017-12-20
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
Nature, 552, 2017
3I6W
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BU of 3i6w by Molmil
Structure and Activation Mechanism of the CHK2 DNA-Damage Checkpoint Kinase
分子名称: Serine/threonine-protein kinase Chk2
著者Pavletich, N.P.
登録日2009-07-07
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structure and activation mechanism of the CHK2 DNA damage checkpoint kinase.
Mol.Cell, 35, 2009
3I6U
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Structure and Activation Mechanism of the CHK2 DNA-Damage Checkpoint Kinase
分子名称: Serine/threonine-protein kinase Chk2
著者Pavletich, N.P.
登録日2009-07-07
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure and activation mechanism of the CHK2 DNA damage checkpoint kinase.
Mol.Cell, 35, 2009
4GOP
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BU of 4gop by Molmil
Structure and Conformational Change of a Replication Protein A Heterotrimer Bound to ssDNA
分子名称: DNA (25-MER), Putative uncharacterized protein, ZINC ION
著者Pavletich, N.P, Jie, F.
登録日2012-08-20
公開日2012-11-28
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure and conformational change of a replication protein A heterotrimer bound to ssDNA.
Genes Dev., 26, 2012
4GNX
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BU of 4gnx by Molmil
Structure of U. maydis Replication protein A bound to ssDNA
分子名称: DNA (25-MER), Putative uncharacterized protein, ZINC ION
著者Pavletich, N.P, Fan, J.
登録日2012-08-17
公開日2013-02-20
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of
To be Published
5WBL
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BU of 5wbl by Molmil
Crystal structure of the Arabidopsis thaliana Raptor in complex with the TOS peptide of human PRAS40
分子名称: Proline-rich AKT1 substrate 1, Regulatory-associated protein of TOR 1
著者Pavletich, N.P, Jiang, X.
登録日2017-06-29
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
Nature, 552, 2017
5WBH
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BU of 5wbh by Molmil
Structure of the FRB domain of mTOR bound to a substrate recruitment peptide of S6K1
分子名称: Ribosomal protein S6 kinase beta-1, Serine/threonine-protein kinase mTOR
著者Pavletich, N.P, Yang, H.
登録日2017-06-29
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
Nature, 552, 2017
5WBK
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BU of 5wbk by Molmil
Crystal structure of the arabidopsis thaliana Raptor in complex with the TOS peptide of human S6K1
分子名称: Regulatory-associated protein of TOR 1, Ribosomal protein S6 kinase beta-1
著者Pavletich, N.P, Jiang, X.
登録日2017-06-29
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.
Nature, 552, 2017
6VAF
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BU of 6vaf by Molmil
Structure of mono-ubiquitinated FANCD2 bound to non-ubiquitinated FANCI and to DNA
分子名称: DNA (29-MER), Fanconi anemia group D2 protein, Fanconi anemia, ...
著者Pavletich, N.P.
登録日2019-12-17
公開日2020-03-18
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献DNA clamp function of the monoubiquitinated Fanconi anaemia ID complex.
Nature, 580, 2020
6VAE
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BU of 6vae by Molmil
Mono-ubiquitinated Fanconi Anemia ID complex bound to ICL DNA
分子名称: DNA (29-MER), Fanconi anemia group D2 protein, Fanconi anemia, ...
著者Pavletich, N.P.
登録日2019-12-17
公開日2020-03-18
最終更新日2020-04-22
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献DNA clamp function of the monoubiquitinated Fanconi anaemia ID complex.
Nature, 580, 2020
6VAA
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BU of 6vaa by Molmil
Structure of the Fanconi Anemia ID complex bound to ICL DNA
分子名称: DNA (26-MER), DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ...
著者Pavletich, N.P.
登録日2019-12-17
公開日2020-03-18
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献DNA clamp function of the monoubiquitinated Fanconi anaemia ID complex.
Nature, 580, 2020
6VAD
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BU of 6vad by Molmil
Fanconi Anemia ID complex
分子名称: Fanconi anemia group D2 protein, Fanconi anemia, complementation group I
著者Pavletich, N.P.
登録日2019-12-17
公開日2020-03-18
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献DNA clamp function of the monoubiquitinated Fanconi anaemia ID complex.
Nature, 580, 2020
3S51
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BU of 3s51 by Molmil
Structure of FANCI
分子名称: Fanconi anemia group I protein homolog
著者Pavletich, N.P.
登録日2011-05-20
公開日2011-07-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of the FANCI-FANCD2 complex: insights into the Fanconi anemia DNA repair pathway.
Science, 333, 2011
3S4W
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BU of 3s4w by Molmil
Structure of the FANCI-FANCD2 complex
分子名称: Fanconi anemia group D2 protein homolog, Fanconi anemia group I protein homolog
著者Pavletich, N.P.
登録日2011-05-20
公開日2011-07-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.408 Å)
主引用文献Structure of the FANCI-FANCD2 complex: insights into the Fanconi anemia DNA repair pathway.
Science, 333, 2011
3S4Z
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BU of 3s4z by Molmil
Structure of a Y DNA-FANCI complex
分子名称: dna repair 1
著者Pavletich, N.P.
登録日2011-05-20
公開日2011-07-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (7.8 Å)
主引用文献Structure of the FANCI-FANCD2 complex: insights into the Fanconi anemia DNA repair pathway.
Science, 333, 2011
4RIA
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BU of 4ria by Molmil
FAN1 Nuclease bound to 5' phosphorylated nicked DNA
分子名称: BARIUM ION, DNA (5'-D(*TP*TP*TP*TP*TP*TP*G*AP*GP*GP*CP*GP*TP*G)-3'), DNA (5'-D(P*AP*GP*AP*CP*TP*CP*CP*TP*C)-3'), ...
著者Pavletich, N.P, Wang, R.
登録日2014-10-05
公開日2014-12-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1.
Science, 346, 2014
4RID
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BU of 4rid by Molmil
Human FAN1 nuclease
分子名称: Fanconi-associated nuclease 1
著者Pavletich, N.P, Wang, R.
登録日2014-10-05
公開日2014-12-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1.
Science, 346, 2014
4RIC
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BU of 4ric by Molmil
FAN1 Nuclease bound to 5' hydroxyl (dT-dT) single flap DNA
分子名称: CALCIUM ION, DNA (5'-D(*GP*CP*TP*GP*AP*GP*GP*AP*GP*TP*CP*T)-3'), DNA (5'-D(*TP*TP*AP*GP*CP*CP*AP*CP*GP*CP*CP*TP*AP*GP*AP*CP*TP*CP*CP*TP*C)-3'), ...
著者Pavletich, N.P, Wang, R.
登録日2014-10-05
公開日2014-12-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1.
Science, 346, 2014
4RI9
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BU of 4ri9 by Molmil
FAN1 Nuclease bound to 5' phosphorylated p(dT)/3'(dT-dT-dT-dT-dT-dT-dT-dT) double flap DNA
分子名称: BARIUM ION, DNA (5'-D(*TP*TP*TP*TP*TP*TP*GP*AP*GP*GP*CP*GP*TP*G)-3'), DNA (5'-D(P*AP*GP*AP*CP*TP*CP*CP*TP*CP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ...
著者Pavletich, N.P, Wang, R.
登録日2014-10-05
公開日2014-12-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1.
Science, 346, 2014

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